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Potential covalent SARS-CoV-2 spike protein inhibitors

There remains a significant need for new and effective drugs that can be used to treat COVID-19.

23 Sep 2021

How SARS-CoV-2 spike binds to multiple host receptors

Researchers from the Genos Glycoscience Research Laboratory in Croatia have recently investigated the sites that the S protein is capable of binding with.

23 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

Early weight loss may protect future fertility of young boys with obesity

Reproductive function in boys with obesity may be improved through weight loss, which could protect their fertility in adulthood, according to research presented today at the 59th Annual European Society for Paediatric Endocrinology Meeting.

23 Sep 2021

COVID-19 transmission is higher with warm weather and increased visits to indoors public places, study finds

A new study finds that environmental factors and human mobility predict seasonal changes in COVID-19 rates, just as in influenza and similar diseases.

23 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

NIH-funded project to test light therapies to combat Alzheimer’s debilitating effects

Alzheimer's disease is a mind-robbing brain disorder that affects nearly 6.2 million older Americans. Despite decades of research on high-tech drugs, diets, and crossword puzzles, scientists have yet to discover a highly effective treatment for patients.

23 Sep 2021

Insulin resistance linked to an increased risk of major depressive disorder

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing major depressive disorder.

23 Sep 2021

New methodology for evaluating transmissibility and competitive advantages of co-circulating SARS-CoV-2 variants

A new study examines how SARS-CoV-2 variants confer a competitive advantage on the virus, fueling further transmission and mortality.

23 Sep 2021

New program sets out to change the European landscape for emerging medical radionuclides

The European medical radionuclides programme sets out to substantially change the European landscape for novel and emerging medical radionuclides.

23 Sep 2021

New discovery may offer a promising avenue for study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

Differences in blood gene expression among patients with varying COVID-19 severity

A new study published on the medRxiv* pre-print server and currently undergoing peer-review aims to answer this question through whole blood transcriptomics of individuals with varying degrees of COVID-19 severity. Transcriptomics, done by RNA sequencing, gives insights into the genes expressed in a cell at a given time point. It gives an analysis of all RNA molecules within a cell, in this case, whole blood.

23 Sep 2021

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

In a paper, the vaccine-induced cellular and immune response of MS patients receiving a range of therapies are assessed.

23 Sep 2021

Antibody kinetics in recovered COVID-19 patients

Researchers from Tel Aviv University have been examining the kinetics of antibodies in recovered COVID-19 patients.

23 Sep 2021

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining and causes death in up to a third of the cases.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Researchers discover potential Achilles heel of pediatric acute myeloid leukemia

Researchers at Baylor College of Medicine and Texas Children's Hospital have uncovered a potential Achilles heel of acute myeloid leukemia (AML) in children that could lead to new treatments for this devastating disease.

23 Sep 2021

Bubble and droplet formation theory inspires a framework for engineering living cells

The heady math that describes how bubbles form in a glass of Champagne has inspired a framework for engineering living cells.

23 Sep 2021

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Findings from a national study by researchers at Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and external collaborators suggest that sex and age are crucial factors in the care and survival of patients with malignant brain tumors and other central nervous systems (CNS) cancers.

23 Sep 2021

B Cell News and Research

Potential covalent SARS-CoV-2 spike protein inhibitors

How SARS-CoV-2 spike binds to multiple host receptors

Design of mRNA vaccines to combat COVID-19

Early weight loss may protect future fertility of young boys with obesity

COVID-19 transmission is higher with warm weather and increased visits to indoors public places, study finds

New discovery offers clues to overcoming resistance to cancer therapies

NIH-funded project to test light therapies to combat Alzheimer’s debilitating effects

Insulin resistance linked to an increased risk of major depressive disorder

New methodology for evaluating transmissibility and competitive advantages of co-circulating SARS-CoV-2 variants

New program sets out to change the European landscape for emerging medical radionuclides

New discovery may offer a promising avenue for study of multiple sclerosis

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

Differences in blood gene expression among patients with varying COVID-19 severity

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

Antibody kinetics in recovered COVID-19 patients

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

Study provides novel insights into how KLF4 influences gene expression

Researchers discover potential Achilles heel of pediatric acute myeloid leukemia

Bubble and droplet formation theory inspires a framework for engineering living cells

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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