Research News and Research

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EPHA3 mutations may be important drivers of lung cancers

Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors.

31 Jul 2012

Gluconeogenesis severely compromised in HCC by IL6-Stat3-mediated activation of miR-23a

As liver cancer develops, tumor cells lose the ability to produce and release glucose into the bloodstream, a key function of healthy liver cells for maintaining needed blood-sugar levels.

31 Jul 2012

Viewpoints: Health law no threat to innovation; Failure to expand Medicaid would 'doom' thousands; Don't stigmatize mentally ill

For better or worse, the Democrats incorporated a good deal of mainstream Republican thinking about health care reform from the past decade, including mandated coverage and health insurance exchanges, into the Affordable Care Act. This leaves the GOP, embarrassingly, with little to say about what is wrong with the act.

31 Jul 2012

Study finds brain structural variations in people with highly superior autobiographical memory

UC Irvine scientists have discovered intriguing differences in the brains and mental processes of an extraordinary group of people who can effortlessly recall every moment of their lives since about age 10.

31 Jul 2012

ATP1A3 gene mutations responsible for alternating hemiplegia of childhood

Alternating hemiplegia of childhood (AHC) is a rare disorder that usually begins in infancy, with intermittent episodes of paralysis and stiffness, first affecting one side of the body, then the other. Symptoms mysteriously appear and disappear, again and again, and affected children often experience dozens of episodes per week. As they get older, children fall progressively behind their peers in both intellectual abilities and motor skills, and more than half develop epilepsy.

31 Jul 2012

Roundup: N.J. public may decide if judges should pay more for health care; Ore. Medicaid experiment to launch; Uncertainty around Va. abortion clinic rules

The New Jersey State Assembly is set to consider a measure that would allow voters to decide whether New Jersey judges should pay more for their pensions and health benefits. The state Supreme Court ruled last week that judges don't have to contribute more toward pensions and health care despite a new law requiring them to do so. The court said the law diminishes judges' salaries, which are protected by state law.

31 Jul 2012

New drug shows promise for Long QT syndrome

Long QT syndrome, which results from genetic mutation or certain medications, can cause the heart to beat chaotically and the affected person to die suddenly. The chaotic heartbeat is due to abnormal electrical activity in the heart. In an electrocardiogram test, this abnormality appears as a wider-than-normal QT interval, a pattern of "hills" in a map of peaks and valleys corresponding to the heart contracting and relaxing.

30 Jul 2012

Burn wound MSCs potential source for skin grafting

Study findings suggest that burn wound eschar-derived mesenchymal cells represent a population of multipotent stem cells, which could be a new resource for engineering approaches to heal burn wounds.

30 Jul 2012

Cancer therapy provides relief for painful foot condition

Research shows that external beam radiation therapy, similar to that used in treating cancer, provides effective pain relief for patients with plantar fasciitis.

30 Jul 2012

Childhood deprivation linked to rheumatoid arthritis in adults

Adults with rheumatoid arthritis are more likely to have grown up in a low socioeconomic environment during childhood than those without RA, a large US case–control study shows.

30 Jul 2012

HPV co-testing prospect for HIV-infected women

The risk for cervical precancer and cancer is similar in HIV-infected and HIV-uninfected women with normal cervical cytology and no evidence of oncogenic human papillomavirus infection, research shows.

30 Jul 2012

Gene for sporadic paralysis of childhood discovered

Researchers have identified de novo mutations in the ATP1A3 gene that they believe are responsible for a sporadic childhood paralysis known as alternating hemiplegia of childhood.

30 Jul 2012

Enoxaparin prevents PVT in advanced cirrhosis

Enoxaparin significantly reduces portal vein thrombosis and increases overall survival in patients with advanced cirrhosis, the results of an Italian study show.

30 Jul 2012

Hydroxychloroquine fails to modify HIV in patients not taking ART

The use of hydroxychloroquine does not reduce CD8 cell activation in HIV-infected patients not taking antiretroviral therapy, research shows.

30 Jul 2012

Conception plans miscarry with sperm DNA damage

Sperm with damaged DNA are more likely to cause spontaneous pregnancy loss, report researchers.

30 Jul 2012

Early CT ‘definitive’ for subarachnoid hemorrhage diagnosis

Cerebrospinal fluid analysis is only necessary for patients with thunderclap headache and a negative computed tomography scan if they undergo imaging more than 6 hours after headache onset, research suggests.

30 Jul 2012

New research indicates molecular signaling from end to end in peripheral nerve cells

When the longest cells in the body are injured at their farthest reaches, coordinating the cells' repair is no easy task. This is in part because these peripheral nerve cells can be extremely long - up to one meter in adult humans - which is a lot of distance for a molecular distress signal to cover in order to reach the "command center" of the cell's nucleus.

30 Jul 2012

CNN examines progress, challenges in global polio eradication efforts

"Health efforts are close to wiping out polio, but two significant challenges remain: money and the operational logistics of getting the vaccine to people who need it," CNN writes in an article examining "how far we've come with polio and what's left to be done."

30 Jul 2012

Study sheds light on complexities of cancer genetics

By studying fruit flies, scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have successfully devised a fast and cost-saving way to uncover genetic changes that have a higher potential to cause cancer.

30 Jul 2012

XIX International AIDS Conference concludes in Washington, D.C.

"The XIX International AIDS Conference [AIDS 2012] drew to a close Friday without the physical presence of President Obama but with a full cast of other high-profile U.S. politicians who expressed their commitment to ending the disease," CQ HealthBeat reports (Norman, 7/27).

30 Jul 2012

Research News and Research

EPHA3 mutations may be important drivers of lung cancers

Gluconeogenesis severely compromised in HCC by IL6-Stat3-mediated activation of miR-23a

Viewpoints: Health law no threat to innovation; Failure to expand Medicaid would 'doom' thousands; Don't stigmatize mentally ill

Study finds brain structural variations in people with highly superior autobiographical memory

ATP1A3 gene mutations responsible for alternating hemiplegia of childhood

Roundup: N.J. public may decide if judges should pay more for health care; Ore. Medicaid experiment to launch; Uncertainty around Va. abortion clinic rules

New drug shows promise for Long QT syndrome

Burn wound MSCs potential source for skin grafting

Cancer therapy provides relief for painful foot condition

Childhood deprivation linked to rheumatoid arthritis in adults

HPV co-testing prospect for HIV-infected women

Gene for sporadic paralysis of childhood discovered

Enoxaparin prevents PVT in advanced cirrhosis

Hydroxychloroquine fails to modify HIV in patients not taking ART

Conception plans miscarry with sperm DNA damage

Early CT ‘definitive’ for subarachnoid hemorrhage diagnosis

New research indicates molecular signaling from end to end in peripheral nerve cells

CNN examines progress, challenges in global polio eradication efforts

Study sheds light on complexities of cancer genetics

XIX International AIDS Conference concludes in Washington, D.C.

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