Animal Model News and Research

RSS

Rare DNA alteration may increase rsk of multiple sclerosis

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation - a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.

6 Jun 2016

Shift work alters internal body clock and leads to strokes, serious brain implications

Statistics show that some 15 million Americans don't work the typical nine-to-five. These employees (or shift workers), who punch in for graveyard or rotating shifts, are more prone to numerous health hazards, from heart attacks to obesity, and now, new research, published in Endocrinology, shows shift work may also have serious implications for the brain.

2 Jun 2016

Researchers identify potential therapeutic target against oncogenic viral infection

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in immune-compromised individuals.

1 Jun 2016

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research.

24 May 2016

Raman spectroscopic technique helps detect unique cellular changes that occur following radiation

The Irving K Barber School of Arts and Sciences at the University of British Columbia, Canada, hosts a multidisciplinary group of physics, engineering and radiation oncology scientists.

From Renishaw plc - Spectroscopy 24 May 2016

Antimicrobial agent triclosan can rapidly disrupt gut bacterial communities

A new study suggests that triclosan, an antimicrobial and antifungal agent found in many consumer products ranging from hand soaps to toys and even toothpaste, can rapidly disrupt bacterial communities found in the gut.

24 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

Innovative research technique may help understand early stage kidney disease

UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

19 May 2016

Drug-repositioning strategy could help combat Chikungunya virus

Since 2013, the mosquito-borne Chikungunya virus has spread rapidly through South America and the Caribbean, and is now threatening Southern Europe and the southern US.

13 May 2016

Soluble factors from white blood cells may improve tissue healing after skin grafting

Extensive burn injuries are usually treated by transplanting layers of skin from other parts of the body. Although this is a commonly used method, the wounds do not always heal completely.

12 May 2016

Low adiponectin levels may lead to development of PTSD symptoms

Individuals with post-traumatic stress disorder (PTSD) relive past traumas again and again, bound in a virtual prison of their memories.

12 May 2016

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Two mouse models of Zika virus infection in pregnancy have been developed by a team of researchers at Washington University School of Medicine in St. Louis. In them, the virus migrated from the pregnant mouse's bloodstream into the placenta, where it multiplied, then spread into the fetal circulation and infected the brains of the developing pups.

12 May 2016

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

12 May 2016

TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Novel animal model helps understand mechanisms that lead to multiple myeloma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed an animal model that allows them to better understand the mechanisms that lead to the development of multiple myeloma, a hematologic cancer of plasma cells, and the amyloidosis that sometimes accompanies it. The study was published in the journal Scientific Reports.

6 May 2016

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.

3 May 2016

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

The cannabinoid type 2 receptor - also called "CB2 receptor" - is a special membrane protein. Its function is to receive chemical signals that control cellular activity. "Until now, this receptor was considered part of the immune system without function in nerve cells.

3 May 2016

Promising method may help identify new antimicrobials to target CRE infection

In recent years, hospitals have reported dramatic increases in the number of cases of the highly contagious, difficult-to-treat, and often deadly antibiotic-resistant bacteria carbapenem-resistant Enterobacteriaceae (CRE). Now, investigators at Beth Israel Deaconess Medical Center have developed a promising method of identifying new antimicrobials that target these organisms. The research is published in April issue of the journal ASSAY and Drug Development Technologies.

30 Apr 2016

Scientists show how HIV enters female reproductive tract

Finding the vulnerable points where HIV enters the female reproductive tract is like searching for needles in a haystack. But Northwestern Medicine scientists have solved that challenge by creating a glowing map of the very first cells to be infected with a HIV-like virus.

28 Apr 2016

First-ever vaccine to combat Leishmaniasis under development

As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease - Leishmaniasis - from gaining a similar foothold in the Americas.

27 Apr 2016

Animal Model News and Research

Rare DNA alteration may increase rsk of multiple sclerosis

Shift work alters internal body clock and leads to strokes, serious brain implications

Researchers identify potential therapeutic target against oncogenic viral infection

ANK3 and other genes may play key role in affecting mood, stress and longevity

Raman spectroscopic technique helps detect unique cellular changes that occur following radiation

Antimicrobial agent triclosan can rapidly disrupt gut bacterial communities

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Innovative research technique may help understand early stage kidney disease

Drug-repositioning strategy could help combat Chikungunya virus

Soluble factors from white blood cells may improve tissue healing after skin grafting

Low adiponectin levels may lead to development of PTSD symptoms

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Brazilian strain of Zika virus can cause severe birth defects

TSRI scientists design potential drug candidate to treat triple negative breast cancer

Novel animal model helps understand mechanisms that lead to multiple myeloma

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

Promising method may help identify new antimicrobials to target CRE infection

Scientists show how HIV enters female reproductive tract

First-ever vaccine to combat Leishmaniasis under development

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News