Antibiotic Resistance News and Research

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MGB Biopharma begins MGB-BP-3 Phase I clinical trial for treatment of Clostridium difficile infections

MGB Biopharma, a biopharmaceutical company developing a truly novel class of anti-infectives, to address the major global problem of antibiotic resistance today announces that the first group of healthy male volunteers have been dosed in a Phase I clinical trial assessing the safety and tolerability of an oral formulation of MGB-BP-3, for use in the treatment of Clostridium difficile infections.

21 Jul 2015

NDSU assistant professor receives NIH grant to study regulation of transporters in Gram-negative bacteria

Christopher Colbert, assistant professor of biochemistry at North Dakota State University, Fargo, has received a $348,000 grant award from the National Institute of General Medical Sciences of the National Institutes of Health to conduct research on structure-function relationships of iron transport and transcriptional regulation in Gram-negative bacteria.

20 Jul 2015

Multidrug-resistant bacteria can naturally relinquish its ability to resist antibiotics

Infections with one of the most troublesome and least understood antibiotic-resistant "superbugs" are increasing at alarming rates, particularly in health-care settings.

14 Jul 2015

Dr. Jian-Dong Li receives $1.6 million to develop novel therapeutic targets to treat middle-ear infections

Dr. Jian-Dong Li, a professor and director of the Institute for Biomedical Sciences at Georgia State University and a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity, has received a five-year, $1.6 million federal grant to develop novel anti-inflammatory therapeutics against middle-ear infections.

2 Jul 2015

Aridis' Aerucin gets FDA Fast Track Designation for treatment of hospital-acquired and ventilator-associated pneumonia

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel therapies for infectious diseases, announced today that the U.S. Food and Drug Administration granted Fast Track Designation to its fully human monoclonal antibody Aerucin for the treatment of hospital-acquired and ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

30 Jun 2015

IPs spend more time in collecting and reporting hospital infection data than protecting patients

Collecting and reporting hospital infection data to federal health agencies takes more than 5 hours each day, at the expense of time needed to ensure that frontline healthcare personnel are adhering to basic infection prevention practices such as hand hygiene, according to a recent case study, to be presented on Saturday, June 27 at the 42nd Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

26 Jun 2015

Pilot antibiotic program at pediatric long-term care facility decreases use of topical antibiotic

A pilot antibiotic stewardship program at a pediatric long-term care facility brought about a 59 percent decrease in use of a topical antibiotic and an 83 percent decrease in orders for antibiotics without proper documentation during a six-month period, according to a new study.

26 Jun 2015

World MRSA Day Kickoff Event and Global C. difficile Summit to be held on September 26, 2015 in Illinois

Methicillin-resistant Staphyloccocus aureus (MRSA), the antibiotic resistant form of Staphylococcus aureus is rampant in U.S. healthcare facilities, in the community, in livestock and in the environment.

25 Jun 2015

Researchers identify fast and accurate approach to diagnose respiratory tract infection

Researchers from the University of Manchester are part of a team that has identified an important new approach to diagnose infections in critically ill patients rapidly and accurately.

25 Jun 2015

New research examines antibiotic choice for treating children with community-acquired pneumonia

New Vanderbilt-led research shows hospitals are doing a better job of using antibiotics less commonly associated with antibiotic resistance to treat children hospitalized with community-acquired pneumonia (CAP).

23 Jun 2015

Australian researchers launch global search to discover antibiotics against superbug bacteria

Australian researchers from The University of Queensland have launched a global search to discover antibiotics capable of combating superbug bacteria that are resistant to current antibiotics.

19 Jun 2015

Survey finds first evidence of MRSA in sausages, minced pork from supermarkets in the UK

A survey carried out earlier this year has found the first evidence of the 'superbug' bacteria Methicillin-Resistant Staphylococcus aureus (MRSA) in sausages and minced pork obtained from supermarkets in the UK. However, researchers stress that this does not pose a significant immediate risk to the public.

19 Jun 2015

DSM Sinochem Pharmaceuticals supports WHO’s ‘Call to Action’ on antimicrobial resistance

Following the Global Health Summit in Uppsala (Sweden) on 2-3 June, 2015, DSM Sinochem Pharmaceuticals pledged its commitment to the WHO’s ‘Call to Action’ on antimicrobial resistance issued at the Summit. One of the biggest opportunities to maintain the effectiveness and availability of antibiotics is responsible waste management, to date a highly undervalued dimension in the debate around resistance. DSP promised to use its expertise and influence in this area to help curb antimicrobial resistance.

16 Jun 2015

Scientists develop new technique to analyze bacterial populations

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence. The new methods hold the promise of a potent new tool to offset the growing challenge of antibiotic resistance by bacterial pathogens.

16 Jun 2015

Study shows bacteriophages remain active against P. aeruginosa infection after nebulization

bacteriophage-based antibacterial therapies to treat drug resistant infections, today announced new data demonstrating that bacteriophages remain active against Pseudomonas aeruginosa (P. aeruginosa) after nebulization.

15 Jun 2015

Researchers working on new system that can detect patient's antibiotic resistance in 30 minutes

A new device being developed by medical experts will transform the time it takes to detect antibiotic resistance in patients from several days to just half an hour.

12 Jun 2015

Johns Hopkins researcher to help address solutions to antibiotic-resistant bacteria at White House

Johns Hopkins infectious disease researcher Sara Cosgrove, M.D., M.S., has been tapped by the White House to help address solutions to the ever-growing problem of antibiotic-resistant bacteria.

11 Jun 2015

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Contrary to current medical dogma, researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors.

11 Jun 2015

UK scientists explore the impact of antibiotic resistant bacteria on surfers

UK Scientists are about to begin an innovative study that will shed light on how surfers exposed to human sewage and diffuse pollution in seawater might be affected by antibiotic resistant bacteria.

10 Jun 2015

Whole genome sequencing can help implement rapid-response infection control protocols

Whole genome sequencing can quickly isolate the specific strain of bacteria causing an outbreak, identify the source of contamination, and enable rapid infection prevention to stop the spread of infection, according to a study published today.

9 Jun 2015