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Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Different respiratory diseases associated with chronic cough create distinct microbial imbalances in the lower airways of children, according to a study led by researchers at NYU School of Medicine.

26 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

The governing board of the California Institute for Regenerative Medicine unanimously approved this week two grants worth more than $2.2 million to University of California San Diego School of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.

20 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

AbbVie, a research-based global biopharmaceutical company, today announced it submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for venetoclax in combination with a hypomethylating agent or in combination with low-dose cytarabine for the treatment of newly diagnosed patients with acute myeloid leukemia who are ineligible for intensive chemotherapy.

20 Jul 2018

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

The U.S. Food and Drug Administration today approved Kisqali (ribociclib) in combination with an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy.

19 Jul 2018

Support circle: Family caregivers share stories and tips to ease Alzheimer’s toll

Vicki Bartholomew started a support group for wives who are caring for a husband with Alzheimer’s disease because she needed that sort of group herself.

11 Jul 2018

Infants have less severe food-induced anaphylaxis unlike older children

Symptoms of food-induced anaphylaxis in infants are much less severe than in toddlers and older children, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago published in the Annals of Allergy, Asthma and Immunology.

11 Jul 2018

Oxygen therapy could help prevent dementia in people with breathing difficulties

Breathing in additional oxygen improves the function of blood vessels in the brain of people with breathing difficulties caused by lung conditions, according to new research published in Experimental Physiology.

6 Jul 2018

Northwestern Memorial Hospital completes its first robotic-assisted minimally invasive tracheoplasty

A well-known thoracic surgeon successfully completed Northwestern Memorial Hospital's first robotic-assisted minimally invasive tracheoplasty using the da Vinci Xi Surgical System to help repair the collapse of the central airway including the trachea and bronchi.

3 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Research provides new target to help treat chemotherapy-induced diarrhea

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening.

27 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Men often tolerate stress urinary incontinence for more than two years before seeking medical help - and one-third put up with it for more than five years, making it important for doctors to check for this problem, a new study from UT Southwestern researchers advises.

25 Jun 2018

WVU researcher aims to produce updated whooping cough vaccine

Before the whooping-cough vaccine came into widespread use in the 1940s, about 9,000 American children died from the infection each year. Today, thanks to the vaccine's efficacy, reported cases of whooping cough have dramatically declined and fatalities have dropped to up to 20 children each year.

18 Jun 2018

Cough News and Research

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

CNDA approves KEYTRUDA for treatment of advanced melanoma

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

Support circle: Family caregivers share stories and tips to ease Alzheimer’s toll

Infants have less severe food-induced anaphylaxis unlike older children

Oxygen therapy could help prevent dementia in people with breathing difficulties

Northwestern Memorial Hospital completes its first robotic-assisted minimally invasive tracheoplasty

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

Research provides new target to help treat chemotherapy-induced diarrhea

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Study: Men tolerate stress urinary incontinence for years before seeking medical help

WVU researcher aims to produce updated whooping cough vaccine

Study shows effectiveness of prenatal Tdap vaccine in preventing infant pertussis

New study shows how vitamin A effectively supports lung immunity against TB

Eating honey can reduce serious injuries in children who swallowed button battery, shows study

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