DNA Sequencing News and Research

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Scientists discover new class of small RNAs

Researchers at Cold Spring Harbor Laboratory (CSHL) announced today the discovery of a new class of small RNAs. At the same time, they reported that their discovery suggests the presence of a strikingly novel biochemical pathway for RNA processing in which these and possibly other small RNAs are produced.

27 Jan 2009

Researchers show how anthracycline class of chemotherapeutics block blood vessel growth, slow cancer spread

Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth.

21 Jan 2009

Epigenetics may account for some inherited traits and diseases

Embargoed Until January 18, 2009 at 18:00 Greenwich Mean Time / 13:00 Eastern Standard Time (TORONTO): Scientists at the Centre for Addiction and Mental Health (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also account for some inherited traits and diseases.

19 Jan 2009

Microbes within gut may hold key to one cause of obesity

In terms of diversity and sheer numbers, the microbes occupying the human gut easily dwarf the billions of people inhabiting the Earth.

19 Jan 2009

Gene switch sites found mainly on 'shores,' not just 'islands' of the human genome

Scientists who study how human chemistry can permanently turn off genes have typically focused on small islands of DNA believed to contain most of the chemical alterations involved in those switches.

19 Jan 2009

Scientists explain genetic disease first discovered in Quebec 24 years ago

Scientists at the MUHC and McGill University have identified a gene essential for the uptake of vitamin B12 in human cells.

15 Jan 2009

Discovery of gene that increases susceptibility to Crohn's disease

Researchers at McGill University, the Research Institute of the McGill University Health Centre (RI MUHC) and the McGill University and Génome Québec Innovation Centre, along with colleagues at other Canadian and Belgian institutions, have discovered DNA variations in a gene that increases susceptibility to developing Crohn's disease.

8 Jan 2009

Gene abnormality found to predict childhood leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

8 Jan 2009

Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Discovery of new way for bacteria to transfer toxic genes to unrelated bacterial species

In a laboratory experiment, the scientists from NYU School of Medicine discovered that Staphylococcus aureus, a notorious bacterium that causes toxic shock syndrome and many other types of infections and is the scourge of hospitals nationwide due to its growing antibiotic resistance, could co-opt viral parasites as secret pipelines for transferring toxin genes to vastly different bacterial species.

6 Jan 2009

Blocking mechanism found for antibiotic resistance in bacteria

It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria -- one of the world's most pressing public health problems.

18 Dec 2008

Just a little squeeze lets proteins assess DNA

To find its target, all a protein needs to do is give quick squeezes as it moves along the DNA strand, suggests new research from The University of Arizona in Tucson.

16 Dec 2008

Tracking the molecular pathway to mixed-lineage leukemia

Infants and adults with the blood cancer mixed-lineage leukemia (MLL) typically have a poor prognosis, and most infants die before their first birthdays.

15 Dec 2008

Promising clinical trial for Progeria "premature aging" disease

One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Sunday, Dec. 14, at the American Society for Cell Biology (ASCB)'s annual meeting in San Francisco.

14 Dec 2008