Hyperactivity News and Research

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Positive results from Targacept TC-5619 Phase 2 trial for inattentive-predominant attention deficit/hyperactivity disorder

Targacept, Inc. today announced top-line results from a Phase 2 trial of TC-5619 as a treatment for inattentive-predominant attention deficit/hyperactivity disorder (ADHDi). In the trial, TC-5619 did not meet the primary outcome measure, change from baseline on the inattention subscale of the Conners' Adult ADHD Rating Scale-Investigator-Rated (CAARS-INV), after four weeks of treatment versus placebo.

17 Sep 2012

New study analyses effects of passive smoking during pregnancy on newborns

A new study shows that newborns that have been exposed to nicotine from both active and passive smoking mothers show poor physiological, sensory, motor and attention responses.

15 Sep 2012

Good health helps children with stressful elementary to middle school transitions

Good health helps children with stressful transitions from elementary school to middle school, finds a new study in the Journal of Adolescent Health. Students with chronic conditions such as asthma, obesity, learning disabilities, attention-deficit hyperactivity disorder, and those with health-related needs, were noted to have lower academic performances.

14 Sep 2012

Adolescents with autism spectrum disorder more likely to be bullied

A study based on information collected from 920 parents suggests an estimated 46.3 percent of adolescents with an autism spectrum disorder were the victims of bullying, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication.

4 Sep 2012

Study shows how NCAN gene results in manic symptoms of bipolar disorder

Flying high, or down in the dumps - individuals suffering from bipolar disorder alternate between depressive and manic episodes. Researchers from the University of Bonn and the Central Institute of Mental Health in Mannheim have now discovered, based on patient data and animal models, how the NCAN gene results in the manic symptoms of bipolar disorder. The results have been published in the current issue of "The American Journal of Psychiatry."

1 Sep 2012

ADHD symptoms 'present in most children who stutter'

Over half of school-age children who stutter have sufficient attention deficit/hyperactivity disorder symptoms to warrant referral for clinical evaluation, the results of a US study of parental reports indicates.

22 Aug 2012

Pulvinar regulates communication between clusters of brain cells

A mysterious region deep in the human brain could be where we sort through the onslaught of stimuli from the outside world and focus on the information most important to our behavior and survival, Princeton University researchers have found.

18 Aug 2012

ADHD in girls portends continuing problems, through early adulthood

Girls with Attention Deficit Hyperactivity Disorder (ADHD) - and their families - often look forward to the likely decline in visible symptoms such as fidgety or disruptive behavior as they mature into young women.

15 Aug 2012

Two papers may help identify gene variants that contribute to OCD or Tourette syndrome

Two papers that will appear in the journal Molecular Psychiatry, both receiving advance online release, may help identify gene variants that contribute to the risks of developing obsessive-compulsive disorder (OCD) or Tourette syndrome (TS). Both multi-institutional studies were led by Massachusetts General Hospital (MGH) investigators, and both are the first genome-wide association studies (GWAS) in the largest groups of individuals affected by the conditions.

15 Aug 2012

Persistent and loud snoring associated with problem behaviors in young children

Persistent and loud snoring in young children is associated with problem behaviors, according to a new study published online in Pediatrics.

13 Aug 2012

Manipulating hormone-producing cells in the brain may help control blood sugar levels

Manipulating a group of hormone-producing cells in the brain can control blood sugar levels in the body - a discovery that has dramatic potential for research into weight-loss drugs and diabetes treatment.

10 Aug 2012

Utility of DMDD diagnosis in child psychiatric patients questioned

In children admitted to a psychiatric unit with serious behavioral problems, use of the new diagnosis concept of disruptive mood dysregulation disorder may go some way to reducing diagnoses of bipolar disorder, research shows.

10 Aug 2012

Variations in RORA gene can lead to post-traumatic stress disorder

Investigators at Boston University School of Medicine (BUSM) and Veterans Affairs (VA) Boston Healthcare System have identified a new gene linked to post-traumatic stress disorder (PTSD).

8 Aug 2012

Strong oppositional behaviors associated with drug abuse among children

Children who exhibit oppositional behavior run the risk of becoming addicted to nicotine, cannabis and cocaine whilst Inattention symptoms represent a specific additional risk of nicotine addiction. Nevertheless, hyperactivity in itself does not seem to be associated with any specific risk of substance abuse or dependence.

2 Aug 2012

Elation and irritability increase BD risk

Symptoms of elation and irritability are significantly associated with an increased likelihood for developing bipolar disorder, researchers report.

31 Jul 2012

Evidence for ADHD due to delay in brain development

Is attention-deficit/hyperactivity disorder (ADHD) due to a delay in brain development or the result of complete deviation from typical development? In the current issue of Biological Psychiatry, Dr. Philip Shaw and colleagues present evidence for delay based on a study by the National Institutes of Health.

30 Jul 2012

Researchers use neuroimaging to study brains of preschool children with ADHD symptoms

Young children often have problems paying attention or concentrating, but when are these problems serious enough for parents and teachers to be concerned? According to estimates from the Centers for Disease Control, 1 in 11 school-aged children are diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD), but research suggests that the warning signs often appear even before the demands of school begin.

28 Jul 2012