Immunoglobulin News and Research

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Chasing the elusive dream of a COVID cure

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off — and might never arrive.

15 May 2020

Varied performance of SARS-CoV-2 antibody tests in detecting protective immunity

The performance of commercially available serological tests in real patient samples and the correlates of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provided by IgG antibodies are still a matter of debate. A new bioRxiv preprint paper cross-examines the performance of several assays and proclaims the plaque reduction neutralization test (PRNT) as a method of choice.

11 May 2020

Patients recently recovered from COVID-19 produce virus-specific antibodies

Most newly discharged patients who recently recovered from COVID-19 produce virus-specific antibodies and T cells, suggests a study published on May 3rd in the journal Immunity, but the responses of different patients are not all the same.

5 May 2020

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Fluidic Sciences and Sphere Bio 22 Apr 2020

Nasal smear as screening test for allergic rhinitis

Stuffy noses, itching and fits of sneezing - 130 million people in Europe suffer from hay fever and other forms of allergic rhinitis. Until now, these conditions have typically been diagnosed using blood samples or skin prick tests.

17 Apr 2020

Octapharma USA supports new COVID-19 clinical trial

Octapharma USA is supporting a new investigator initiated clinical trial led by George Sakoulas, M.D. of Sharp Memorial Hospital in San Diego, California focused on treating the most critical patients at the heart of the coronavirus pandemic, those experiencing respiratory failure who become ventilator dependent.

16 Apr 2020

China with the world: COVID-19 experts dialogues - the 4th talk transcript

Q (Prof. Singer): What do you think about the comorbidities and the age of the patients in the treatment of COVID-19? Is the mortality higher in elderly patients as it is reported from recent papers?

From Mindray 15 Apr 2020

Milk allergy - is it overdiagnosed?

A new review published in the journal JAMA Pediatrics in April 2020 raises the concern that there may be a significant overdiagnosis of cow's milk allergy in babies and young children, stemming from the use of current medical recommendations.

13 Apr 2020

New prognostic tool could help improve clinical decision making for leukemia patients

A new prognostic tool predicts how long someone diagnosed with chronic lymphocytic leukemia (CLL) will be able to wait before starting cancer treatment.

8 Apr 2020

New prognostic tool helps leukemia patients plan for cancer treatment

A prognostic tool predicts how long someone diagnosed with chronic lymphocytic leukemia (CLL) can wait before cancer treatment.

8 Apr 2020

Researchers identify the most common characteristics of fatal COVID-19 cases

In a new study, researchers identified the most common characteristics of 85 COVID-19 patients who died in Wuhan, China in the early stages of the coronavirus pandemic.

3 Apr 2020

Patients with hypertension, diabetes and heart disease more likely to die from COVID-19

As the coronavirus disease (COVID-19) evolves, important information emerges, thanks to studies and analyses undertaken by scientists and health experts. With more data available based on patients in actual healthcare settings, scientists have more information on how the virus affects the body and who are at most risk of the disease.

2 Apr 2020

Grifols Announces Formal Collaboration with US Government to Produce the First Treatment Specifically Targeting COVID-19

Grifols today announces that it has entered into a formal collaboration with the US Government alongside other health agencies, to treat COVID-19 disease.

From GRIFOLS U.K. Ltd. 27 Mar 2020

Maternal psychological distress during pregnancy influences child's gut immunity

A woman's mental health during pregnancy has a direct influence on the development of her child's immune system, according to a new study from pediatric researchers at the University of Alberta.

3 Mar 2020

Daratumumab proves effective in patients with relapsed AL amyloidosis

There's a new treatment option available for patients with AL amyloidosis: daratumumab. Studied in a prospective clinical trial, only one of the two clinical trials of this agent in AL amyloidosis worldwide, researchers have found this anti-cancer drug to be well tolerated and effective in patients with relapsed AL amyloidosis when used with appropriate pre- and post-infusion medications.

27 Jan 2020

Study of glycobiology and glycan diagnostics in personalized medicine featured in OMICS special issue

An in-depth look at the science of glycobiology and glycan diagnostics, and their promise in personalized medicine in the current post-genomic era are featured in a special issue of OMICS: A Journal of Integrative Biology, the peer-reviewed interdisciplinary journal published by Mary Ann Liebert, Inc., publishers.

13 Jan 2020

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus.

22 Dec 2019

Scientists explore role of IgG4 Abs in IgG4-related disease

Autoimmune diseases are a medical conundrum. In people with these conditions, the immune system of the body, the designated defense system, starts attacking the cells or organs of its own body, mistaking the self-cells for invading disease-causing cells. Often, the cause for this spontaneous dysfunction is not clear, and hence, treatment of these diseases presents a major and ongoing challenge.

18 Dec 2019

Children with persistent cow's milk allergy are smaller and weigh less than peers

Children who are allergic to cow's milk are smaller and weigh less than peers who have allergies to peanuts or tree nuts, and these findings persist into early adolescence.

16 Dec 2019

Nanosize container can slip inside cells and deliver medicines, gene therapies

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size - even hefty ones attached to the gene-editing tool called CRISPR.

6 Dec 2019