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Researchers reveal pathological mechanisms in congenital myotonic dystrophy

Myotonic dystrophy (DM) is the most common form of genetic muscular dystrophy that begins in adulthood. DM is characterized by progressive muscle wasting and weakness. People with this disorder often have prolonged muscle contractions (myotonic) and are not able to relax certain muscles after use.

12 Dec 2017

Changes in microbiome due to antibiotic exposure may increase risk for inflammatory bowel disease

Exposure to antibiotics in mothers may increase risk for inflammatory bowel diseases in their offspring. This is the finding of a study in mice led by researchers from NYU School of Medicine and published Nov. 27 in the journal Nature Microbiology.

27 Nov 2017

People with depressive symptoms before disaster may experience increase in inflammation

People who exhibit even a few depressive symptoms before a major life stressor, such as a disaster, may experience an increase in inflammation -- a major risk factor for heart disease and other negative health conditions -- after the event, according to new research from Rice University.

23 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial.

21 Sep 2017

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

While immune cells called neutrophils are known to act as infantry in the body's war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of stroke caused by ruptured blood vessels.

20 Sep 2017

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC.

14 Sep 2017

Study uncovers how inflammation contributes to key feature of diabetes

A new study by researchers at the University of Maryland School of Medicine has uncovered how inflammation contributes to a key feature of diabetes, the body's inability to metabolize glucose, a condition known as insulin resistance.

12 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Heart attacks provoke an acute immune response. Leukocytes rush to the heart muscle to remove dead cells and begin building scar tissue. This is followed by a second immune response, the resolving phase that allows healing.

7 Sep 2017

Reducing inflammation without lowering cholesterol significantly lowers rate of recurrent cardiovascular events

The researchers from Brigham and Women's Hospital this week have come up with a new study which shows that reducing the inflammation among patients who have already had a heart attack before could prevent the risk of getting more cardiovascular events. The study is published in the latest issue of the New England Journal of Medicine.

28 Aug 2017

Anti-inflammatory therapy reduces incidence of lung cancer

In most clinical trials for cancer therapy, investigators test treatments in patients with advanced disease. But a recent cardiovascular secondary prevention study has given researchers a unique opportunity: to explore the effectiveness of giving a drug to patients before cancer emerges.

28 Aug 2017

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

The IL-1β inhibitor canakinumab lowers the risk of cardiovascular disease and lung cancer risk by reducing inflammation, according to late-breaking results from the CANTOS trial presented today in a Hot Line - LBT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening

A fast, simple blood test for ulcerative colitis using infrared spectroscopy could provide a cheaper, less invasive alternative for screening compared to colonoscopy, which is now the predominant test, according to a study between the Department of Physics and Astronomy and the Institute for Biomedical Sciences at Georgia State University.

23 Aug 2017

Interleukin 2 News and Research

Researchers reveal pathological mechanisms in congenital myotonic dystrophy

Changes in microbiome due to antibiotic exposure may increase risk for inflammatory bowel disease

People with depressive symptoms before disaster may experience increase in inflammation

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

Study uncovers how inflammation contributes to key feature of diabetes

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Reducing inflammation without lowering cholesterol significantly lowers rate of recurrent cardiovascular events

Anti-inflammatory therapy reduces incidence of lung cancer

Drug reduces inflammation to lower cardiovascular disease and lung cancer risk

Blood test using infrared spectroscopy could provide cheaper, quicker alternative for colitis screening

Study finds that yoga and meditation practices enhance resilience, wellbeing

Scientists show how immune system can be modulated by manipulation of sugar metabolism

Study shows role of cholesterol crystals during heart attack

Research shows how glutamine plays role in regulating cellular differentiation programs

New review examines link between psoriasis and psychiatric illnesses

Researchers uncover immunological mechanism involved in resolution of inflammations

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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