Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Endometrial cancer rates rising alarmingly, particularly among Black women

The numbers are stark and deeply troubling. Endometrial cancer - which develops in the lining of the uterus (womb) and is sometimes called uterine cancer - is on the rise in the U.S. In 1987, there were 35,000 cases annually.

19 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

Sirtuin 6: A potential savior for aging cartilage and osteoarthritis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes."

19 Dec 2023

First case of COVID-caused vocal cord paralysis in teen reported by Mass Eye and Ear doctors

Physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, report the first pediatric case of bilateral vocal cord paralysis after COVID-19 (SARS-CoV-2) infection.

19 Dec 2023

Patient-specific muscle models pave way for personalized neuromuscular therapies

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

19 Dec 2023

Common heart medication causes false positives on Alzheimer's blood test

Researchers from the University of Gothenburg, in collaboration with colleagues from University of Glasgow, present data that the drug Entresto (sacubitril/valsartan) which is commonly used for the treatment of cardiac failure leads to a marked reduction in plasma Aβ ratio, a candidate blood test for Alzheimer's disease (AD).

18 Dec 2023

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

18 Dec 2023

Study links omicron's cellular senescence to inflammation and long-COVID risk

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

15 Dec 2023

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression is a complex disease with physical effects throughout the body.

15 Dec 2023

Cola cure? Study sheds light on soda's potential for common holiday medical emergency

Researchers performed a randomized controlled trial (RCT) to evaluate the safety and effectiveness of cola in relieving esophageal meal bolus impaction.

14 Dec 2023

Scientists unlock secret to repairing malnourished children's guts

A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children's underdeveloped gut microbiomes was superior to a widely used standard therapeutic food.

13 Dec 2023

Study reveals treatment gaps and burden of symptoms among patients with microscopic colitis

It's a hidden cause of diarrhea and the development of the disease is poorly understood. Multiple factors work against the diagnosis of microscopic colitis, an inflammatory digestive disease, because the symptom distress compared to patients with other causes of chronic diarrhea remains unknown.

13 Dec 2023

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

13 Dec 2023

As foundation for ‘excited delirium’ diagnosis cracks, fallout spreads

When Angelo Quinto's family learned that officials blamed his 2020 death on "excited delirium," a term they had never heard before, they couldn't believe it. To them, it was obvious the science behind the diagnosis wasn't real.

13 Dec 2023

Innovative robotic right ventricle developed to mimic heart biomechanics

Researchers modeled the right ventricle (RV) to create a robot replicating right ventricular hemodynamics and biomechanics.

13 Dec 2023

Tat-heat shock protein 10 could rejuvenate aging brains

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus."

12 Dec 2023

Study unlocks protein clues to aggressive lymphoma transformation

Researchers have come one step closer to answering why, in some patients, a type of lymphoma changes from indolent to aggressive, and in particular they are closer to identifying which patients are at high risk of this change happening.

12 Dec 2023

Study identifies key factor in lung and eye damage in preemies

Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing.

11 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Pathology News and Research

Further Reading

Endometrial cancer rates rising alarmingly, particularly among Black women

Autopsy study provides new insights into yellow fever's impact on the heart

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Sirtuin 6: A potential savior for aging cartilage and osteoarthritis

First case of COVID-caused vocal cord paralysis in teen reported by Mass Eye and Ear doctors

Patient-specific muscle models pave way for personalized neuromuscular therapies

Common heart medication causes false positives on Alzheimer's blood test

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Study links omicron's cellular senescence to inflammation and long-COVID risk

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Cola cure? Study sheds light on soda's potential for common holiday medical emergency

Scientists unlock secret to repairing malnourished children's guts

Study reveals treatment gaps and burden of symptoms among patients with microscopic colitis

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

As foundation for ‘excited delirium’ diagnosis cracks, fallout spreads

Innovative robotic right ventricle developed to mimic heart biomechanics

Tat-heat shock protein 10 could rejuvenate aging brains

Study unlocks protein clues to aggressive lymphoma transformation

Study identifies key factor in lung and eye damage in preemies

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News