Stem Cells News and Research

RSS

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other mutations may be neutral passenger mutations that have no impact on cancer development.

30 Aug 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Using human tissue models to improve treatment and diagnosis of heart attacks

A heart attack, or myocardial infarction, is one of the leading causes of mortality worldwide, resulting in 18 million deaths per year.

30 Aug 2022

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial mutations to observe these tiny organelles.

30 Aug 2022

Gothenburg scientists discover possible new cancer treatment target

Researchers at the University of Gothenburg have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice.

30 Aug 2022

Parathyroid hormone administered to tendons promotes meniscus regeneration in rat model

The knee meniscus is an important tissue that protects the joint; if the meniscus is damaged - by sports injury or aging–it often does not heal on its own.

26 Aug 2022

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Scientists funded in part by the National Institutes of Health have generated a mouse embryo model, or embryoid, that develops beyond neurulation—formation of the neural tube, which gives rise to the central nervous system—and closely mirrors natural mouse embryos 8.5 days after fertilization.

25 Aug 2022

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer.

24 Aug 2022

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop.

24 Aug 2022

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Imagine you're trying to do a job and all of the information you need to do it is in a few books at the library.

22 Aug 2022

“Drug factory” implants show promise in eradicating mesothelioma tumors

Rice University and Baylor College of Medicine researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining Rice's cytokine "drug factory" implants and a checkpoint inhibitor drug.

22 Aug 2022

World's first-in-human research using organoid transplantation yields good results

Tokyo Medical and Dental University (TMDU) research team announced on July 7 that it has succeeded in the world's first clinical transplantation of a "mini organ (also called Organoid)" into a patient with "Ulcerative Colitis (UC)".

22 Aug 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

Discovery of a group of latent stem cells could offer a new approach to treat brain and spinal cord injuries

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice. If a similar type of cell exists in humans, they could offer a new therapeutic approach to treat brain and spinal cord injuries.

22 Aug 2022

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Researchers at the University of Illinois Chicago have discovered that increasing the production of new neurons in mice with Alzheimer's disease (AD) rescues the animals' memory defects.

19 Aug 2022

Engineers create the world's tiniest EEG caps for brain organoids

It could be the world's tiniest EEG electrode cap, created to measure activity in a brain model the size of a pen dot. Its designers expect the device to lead to better understanding of neural disorders and how potentially dangerous chemicals affect the brain.

17 Aug 2022

New technique keeps the cells alive during RNA extraction

RNA sequencing allows scientists to study the expression of genes in a cell. Since messenger RNA (mRNA) is generated from a DNA gene, that information can be used to identify the original gene sequence and thus measure the activity of thousands of genes (i.e. the transcriptome) in these cells.

17 Aug 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

Stem Cells News and Research

Further Reading

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

Research provides a major step forward to growing human kidney in a dish

Using human tissue models to improve treatment and diagnosis of heart attacks

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Gothenburg scientists discover possible new cancer treatment target

Parathyroid hormone administered to tendons promotes meniscus regeneration in rat model

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

“Drug factory” implants show promise in eradicating mesothelioma tumors

World's first-in-human research using organoid transplantation yields good results

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Discovery of a group of latent stem cells could offer a new approach to treat brain and spinal cord injuries

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Engineers create the world's tiniest EEG caps for brain organoids

New technique keeps the cells alive during RNA extraction

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

eBook: Integrated solutions for mesenchymal stem cell research and culture eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo