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Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

'Tricked' bacteria open door to new antimicrobial therapies

Scientists have developed a new technique to trick bacteria into revealing hundreds of holes in their cell walls, opening the door for drugs that destroy bacteria’s cells.

14 Oct 2019

California’s new transparency law reveals steep rise in wholesale drug prices

Drugmakers fought hard against California's groundbreaking drug price transparency law, passed in 2017. Now, state health officials have released their first report on the price hikes those drug companies sought to shield.

14 Oct 2019

New study could change the way traumatic brain injuries are treated

Traumatic brain injuries, including concussions, can be caused by anything from sports injuries to battlefield trauma.

14 Oct 2019

Overdose prevention should also focus on alcohol use, study suggests

For several years, the national spotlight has shone on the need to prevent and rapidly treat opioid overdoses. But a new study suggests a need for more focus on the risk of alcohol overdoses among people who use opioids of all kinds, as well as cocaine, marijuana and certain prescription drugs.

14 Oct 2019

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

A pioneering clinical trial will investigate the use of cannabidiol (CBD) - a compound found in the cannabis plant - in people with Parkinson's-related psychosis.

14 Oct 2019

Impress your boss with this course

In this webinar, Dr. Michael W. Dong, Pittcon Short Course Instructor, will review best practices, short cuts, and tricks-of-the-trade to help pharmaceutical and other scientists to become more successful in developing effective HPLC methods (potency and ICH-compliant stability-indicating assays) using method templates and universal generic gradient methods.

From Pittcon 14 Oct 2019

Caution urged in reducing opioids for pain

After years and decades in which healthcare providers were freely prescribing opiates for all sorts of painful conditions, the US Centers for Disease Control and Prevention (CDC) published guidelines to help bring down opioid prescription rates and with them, addiction and overdose-related death rates. Though these were not binding, they urged physicians to be cautious in dealing with opioids when prescribing for pain.

13 Oct 2019

Prescription drug nonadherence linked to food insecurity, study shows

Food insecurity is linked to higher disease rates but not much is known about the reasons for this. A new study of more than 10,000 Canadian households shows that this connection may be at least partially attributed to lack of access to prescription medication.

11 Oct 2019

Brain protein plays a prominent role in the maintenance of chronic pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.

11 Oct 2019

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid.

11 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

The ONCOMMUN Program will receive €900,000 grant to promote well-being in cancer

The ONCOMMUN Program will receive a grant worth 900,000 euros for 2019-2020 by the European Institute of Innovation & Technology which will be used to promote well-being in cancer through new technologies.

11 Oct 2019

Simple way to effectively transport medication into the brain identified

For the first time, scientists have identified a simple way that can effectively transport medication into the brain - which could lead to improved treatments for neurological and neurodegenerative diseases.

11 Oct 2019

Imaging tumor stiffness could aid delivery of treatment to most challenging cancers

Using a non-invasive imaging technique that measures the stiffness of tissues gives crucial new information about cancer architecture and could aid the delivery of treatment to the most challenging tumors, new research shows.

11 Oct 2019

Research finds drugs for better long-term treatment of poorly controlled asthma

The waning effectiveness of drugs over time continues to be a major challenge in treating diseases, including asthma.

11 Oct 2019

Taking the cops out of mental health-related 911 rescues

Every day that Janet van der Laak drives between car dealerships in her sales job, she keeps size 12 shoes, some clothes and a packed lunch — a PB&J sandwich, fruit and a granola bar — beside her in case she sees her 27-year-old son on the streets.

11 Oct 2019

Pittcon 2020 Plenary Lecture announced

Pittcon is pleased to announce Dr. Ziva Cooper as the 2020 Plenary Lecturer. Dr. Cooper’s lecture is entitled Cannabis Constituents as Novel Strategies to Tackle the Opioid Epidemic.

From Pittcon 11 Oct 2019

Researchers develop customized drug treatment to bypass patient’s unique mutation

An unprecedented case at Boston Children's Hospital shows that it's possible to do something that's never been done before: identify a patient's unique mutation, design a customized drug to bypass it, manufacture and test the drug, and obtain permission from the Food and Drug Administration (FDA) to begin treating the patient -- all in less than one year.

11 Oct 2019

UC San Diego's CMCR announces research grants to explore cannabis for medical applications

The Center for Medicinal Cannabis Research (CMCR) at University of California San Diego School of Medicine, the nation's oldest research center for scientific inquiry into the safety and efficacy of cannabis, has announced $3 million in research grants to explore new applications of cannabis for a number of novel medical applications.

11 Oct 2019