Immune System News and Research

RSS

Finding could lead to first effective vaccine against respiratory syncytial virus

Vanderbilt University scientists have contributed to a major finding, reported today in the journal Nature, which could lead to the first effective vaccine against respiratory syncytial virus (RSV), a significant cause of infant mortality.

9 Feb 2014

Some neurologic diseases associated with prenatal exposure to inflammatory immune responses

Johns Hopkins researchers report that fetal mice — especially males — show signs of brain damage that lasts into their adulthood when they are exposed in the womb to a maternal immune system kicked into high gear by a serious infection or other malady. The findings suggest that some neurologic diseases in humans could be similarly rooted in prenatal exposure to inflammatory immune responses.

7 Feb 2014

Rice, UTMB develop diagnostic test for cryptosporidiosis

Bioengineers at Rice University and the University of Texas Medical Branch (UTMB) at Galveston have developed a simple, highly sensitive and efficient test for the diarrheal disease cryptosporidiosis that could have great impact on global health.

7 Feb 2014

Research suggests that male mice may be vulnerable to effects of maternal inflammation than females

Johns Hopkins researchers report that fetal mice - especially males - show signs of brain damage that lasts into their adulthood when they are exposed in the womb to a maternal immune system kicked into high gear by a serious infection or other malady.

7 Feb 2014

Study: Investigational drug effective in reducing mucormycosis infections

With very few treatment options available to fight deadly mucormycosis infections, a new Los Angeles Biomedical Research Institute (LA BioMed) study holds hope for adding to the arsenal of therapies physicians have to combat an increasingly common infection afflicting people with weakened immune systems.

7 Feb 2014

TSRI scientists discover unusual protein that probably helps some bacteria evade immune response

A team led by scientists at The Scripps Research Institute (TSRI) has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target. Protein M, as it is called, probably helps some bacteria evade the immune response and establish long-term infections.

7 Feb 2014

Study provides extensive review of incidence, risk factors and characteristics of skin cancer in people of color

While people of color have a lower risk of developing skin cancer than Caucasians, they are not immune to the disease. In fact, skin cancer is often diagnosed at a more advanced stage in people of color, which can make it more difficult to treat.

6 Feb 2014

TSRI scientists design artificial proteins as a candidate vaccine against RSV

Scientists at The Scripps Research Institute (TSRI) have invented a new method for designing artificial proteins, and have used it to make key ingredients for a candidate vaccine against a dangerous virus, respiratory syncytial virus (RSV), a significant cause of infant mortality.

6 Feb 2014

Study: Rise of tuberculosis in Zimbabwe linked with widespread food shortage

The rise of tuberculosis (TB) in Zimbabwe during the socio-economic crisis of 2008-9 has been linked to widespread food shortage, according to a new study led by Canadian researchers from the University of Toronto Dalla Lana School of Public Health published in PLOS ONE.

6 Feb 2014

Researchers design new vaccine for human-infecting respiratory syncytial virus

Vaccines are the safest, cheapest and most effective way to protect against infectious diseases. But to make a good one is still a challenge, and traditional approaches are now stretched to the limit while fatal diseases, like HIV and malaria, remain without vaccine.

6 Feb 2014

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Incyte Corporation (Nasdaq: INCY) announced today that it has entered into a clinical trial collaboration agreement with Merck, through a Merck subsidiary, to evaluate the safety and efficacy of Incyte's oral indoleamine dioxygenase-1 (IDO1) inhibitor, INCB24360, and Merck's investigational anti-PD-1 immunotherapy, MK-3475, in a Phase I/II study in previously treated metastatic and recurrent non-small cell lung cancer (NSCLC), and other advanced or metastatic cancers.

5 Feb 2014

Study: Ipilimumab with VEGF inhibitors may be potential option for melanoma patients

Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

5 Feb 2014

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer Inc. announced today that it has agreed with Merck & Co., Inc., known as MSD outside the United States and Canada ("Merck"), through two Merck subsidiaries, to explore the therapeutic potential of Merck's investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets.

5 Feb 2014

Scientists develop fully automated system to identify sepsis in infants within hours

New detection methods could shorten the detection of sepsis from days down to only a few hours. Sepsis is a possibly mortal bacterial infection. It affects neonates and young infants more severely since their immune system is not fully developed. Now scientists are developing a fully automated system, which can identify sepsis in infants within hours instead of days.

5 Feb 2014

Discovery may have implications for HIV vaccine research

NIH scientists have discovered a mechanism involved in stabilizing key HIV proteins and thereby concealing sites where some of the most powerful HIV neutralizing antibodies bind, findings with potential implications for HIV vaccine research.

4 Feb 2014

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Researchers from Virginia Commonwealth University (VCU) Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis.

4 Feb 2014

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE - angiotensin-converting enzyme - a naturally occurring protein found in tissues throughout the body.

4 Feb 2014

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

Nearly half of HIV-infected teenagers, young adults forego treatment

Nearly half of HIV-infected teenagers and young adults forego timely treatment, delaying care until their disease has advanced, which puts them at risk for dangerous infections and long-term complications, according to a study led by the Johns Hopkins Children's Center.

4 Feb 2014

High sodium intake correlates with fatness and inflammation in adolescents

Most adolescents consume as much salt as adults - some more than twice the recommended daily allowance - and that high sodium intake correlates with fatness and inflammation regardless of how many calories they consume, researchers report.

3 Feb 2014

Immune System News and Research

Finding could lead to first effective vaccine against respiratory syncytial virus

Some neurologic diseases associated with prenatal exposure to inflammatory immune responses

Rice, UTMB develop diagnostic test for cryptosporidiosis

Research suggests that male mice may be vulnerable to effects of maternal inflammation than females

Study: Investigational drug effective in reducing mucormycosis infections

TSRI scientists discover unusual protein that probably helps some bacteria evade immune response

Study provides extensive review of incidence, risk factors and characteristics of skin cancer in people of color

TSRI scientists design artificial proteins as a candidate vaccine against RSV

Study: Rise of tuberculosis in Zimbabwe linked with widespread food shortage

Researchers design new vaccine for human-infecting respiratory syncytial virus

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Study: Ipilimumab with VEGF inhibitors may be potential option for melanoma patients

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Scientists develop fully automated system to identify sepsis in infants within hours

Discovery may have implications for HIV vaccine research

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

Nearly half of HIV-infected teenagers, young adults forego treatment

High sodium intake correlates with fatness and inflammation in adolescents

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News