Immune System News and Research

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Omeros' OMS721 receives FDA orphan drug designation for prevention of TMAs

Omeros Corporation today announced that OMS721, the company's lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the key regulator of the lectin pathway of the immune system, has received orphan drug designation from the U.S. Food and Drug Administration for prevention of complement-mediated thrombotic microangiopathies.

18 Dec 2013

Researchers produce first definitive evidence that MERS-CoV infects camels

Scientists from the Netherlands and Qatar have produced the first definitive evidence that Middle East respiratory syndrome coronavirus infects camels. The researchers used gene-sequencing techniques to show that three camels from a site where two humans contracted MERS-CoV were infected with the virus.

18 Dec 2013

Research examines link between opioid suppression of immune system and cancer recurrence

18 Dec 2013

Arizona scientists investigate intriguing effects of spaceflight on microbial pathogens

At Arizona State University's Biodesign Institute, Cheryl Nickerson and her team have been investigating the intriguing effects of spaceflight on microbial pathogens.

17 Dec 2013

New projects advance treatments for radiation syndrome, cardiac arrest-induced brain injury and rare blood disorder

The National Institutes of Health today has launched three pre-clinical projects to advance potential new treatments for acute radiation syndrome, brain injury following cardiac arrest and a rare blood disorder called beta thalassemia.

17 Dec 2013

Research: Smoking alters several genes

The fact that smoking means a considerable health risk is nowadays commonly accepted. New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several genes that can be associated with health problems for smokers, such as increased risk for cancer and diabetes

17 Dec 2013

Moderate drinking may bolster our immune system and help fight off infection: Study

Medical science has known for years that people who drink moderate amounts of alcohol actually have a reduced risk of death. In general, they are healthier and have better cardiovascular function that those who don't drink alcohol at all.

17 Dec 2013

Exposure to dust from homes with dogs may alter immune response to allergens

A new study suggests that exposure to dust from homes with dogs may alter the immune response to allergens and other asthma triggers by affecting the composition of the gut microbiome-the community of microbes that naturally colonize the digestive tract.

17 Dec 2013

Neuro-Oncology publishes promising phase 2 results from Agenus’ brain cancer vaccine study

Agenus Inc., a biotechnology company developing novel immune system activating treatments for cancers and infectious diseases, today announced results published from a Phase 2 study demonstrated that more than 90% of the patients treated with Prophage Series G-200 were alive at six months after surgery and 30% were alive at twelve months.

17 Dec 2013

arGEN-X reports that Phase Ib cancer study with ARGX-110 antibody meets translational development goals

arGEN-X announces that the dose-escalation part of a Phase Ib study with its lead antibody ARGX-110 has met its translational development goals: all pre-specified biological activity measures (e.g. target engagement, effector functions, immune-modulation) were met.

17 Dec 2013

Research finds link between opioid-sparing technique and reduced progression of prostate cancer

The methods used to anesthetize prostate cancer patients and control pain when their prostate glands are surgically removed for adenocarcinoma may affect their long-term cancer outcomes, a study led by Mayo Clinic has found. Opioids, painkillers commonly given during and after surgery, may suppress the immune system's ability to fight cancer cells.

17 Dec 2013

Scientists identify protein complex essential for jumpstarting immune response during infection

St. Jude Children's Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the scientific journal Immunity.

17 Dec 2013

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

University of Utah researchers have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis. The finding implicates a new class of genes in arthritis progression, potentially opening doors to new treatment options.

17 Dec 2013

Professor wins U.S. Patent for use of antioxidant compound used in treatment of obesity

A Skidmore College alumnus and professor have been awarded U.S. Patent No. 8,598,150 for use of an antioxidant compound that shows promise in the treatment of obesity and related disorders, such as type-2 diabetes.

17 Dec 2013

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Testing the efficacy of vaccines in clinical trials takes years, even decades. Yet challenging infections like HIV, malaria and dengue are striking today. To speed up vaccine testing, scientists at the Emory Vaccine Center have established a goal of creating a "vaccine gene chip."

17 Dec 2013

Research finds reduced allergy risk among children raised with dogs from birth

Children's risk for developing allergies and asthma is reduced when they are exposed in early infancy to a dog in the household, and now researchers have discovered a reason why.

17 Dec 2013

Moderate consumption of alcohol can improve immune response to vaccination

It's the time of year when many of us celebrate the holidays with festive foods and drinks, including alcohol. No better time then to ask if it is true, as is widely held, that moderate consumption of alcohol is beneficial to health.

16 Dec 2013

Glioblastoma multiforme patients treated with experimental vaccine show improved survival

Patients with recurrent glioblastoma multiforme treated with an experimental vaccine made from the patient's own resected tumor tissue showed an improved survival compared with historical patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro-Oncology and accompanied by an editorial highlighting the importance of the trial.

16 Dec 2013

Experimental drug that targets macrophages decreases cancer's growth

An experimental drug that targets macrophages, a type of immune cells, in the microenvironment surrounding the lethal brain tumor glioblastoma multiforme decreased the cancer's growth and extended survival of laboratory mice with the cancer, scientists will report on Tuesday Dec. 17, at the American Society for Cell Biology annual meeting in New Orleans.

16 Dec 2013

OncoSec Medical reports positive interim data from OMS-I100 Phase 2 trial for metastatic melanoma

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy to treat solid tumors, today announced positive interim data from its ongoing Phase 2 trial of OMS-I100 in the treatment of metastatic melanoma. The results were presented by principal investigator Adil Daud, MD, at the Advances in Cancer Immunotherapy meeting at the University of California San Francisco.

16 Dec 2013

Immune System News and Research

Omeros' OMS721 receives FDA orphan drug designation for prevention of TMAs

Researchers produce first definitive evidence that MERS-CoV infects camels

Research examines link between opioid suppression of immune system and cancer recurrence

Arizona scientists investigate intriguing effects of spaceflight on microbial pathogens

New projects advance treatments for radiation syndrome, cardiac arrest-induced brain injury and rare blood disorder

Research: Smoking alters several genes

Moderate drinking may bolster our immune system and help fight off infection: Study

Exposure to dust from homes with dogs may alter immune response to allergens

Neuro-Oncology publishes promising phase 2 results from Agenus’ brain cancer vaccine study

arGEN-X reports that Phase Ib cancer study with ARGX-110 antibody meets translational development goals

Research finds link between opioid-sparing technique and reduced progression of prostate cancer

Scientists identify protein complex essential for jumpstarting immune response during infection

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

Professor wins U.S. Patent for use of antioxidant compound used in treatment of obesity

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Research finds reduced allergy risk among children raised with dogs from birth

Moderate consumption of alcohol can improve immune response to vaccination

Glioblastoma multiforme patients treated with experimental vaccine show improved survival

Experimental drug that targets macrophages decreases cancer's growth

OncoSec Medical reports positive interim data from OMS-I100 Phase 2 trial for metastatic melanoma

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