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Merck, PDS Biotechnology enter licensing agreement for Versamune

PDS Biotechnology Corporation announced today that they have entered into an exclusive worldwide licensing agreement with Merck KGaA, Darmstadt, Germany, for use of PDS Biotechnology's novel Versamune nanotechnology platform in two of Merck's investigational antigen-specific cancer immunotherapies currently in pre-clinical development.

9 Jul 2012

Novel gene therapy approach may treat dysferlinopathies

The challenge of treating patients with genetic disorders in which a single mutated gene is simply too large to be replaced using traditional gene therapy techniques may soon be a thing of the past. A Nationwide Children's Hospital study describes a new gene therapy approach capable of delivering full-length versions of large genes and improving skeletal muscle function. The strategy may hold new hope for treating dysferlinopathies and other muscular dystrophies.

9 Jul 2012

Toyota, Cincinnati Children's expand Buckle Up for Life education program

Responding to disproportionate rates of African American and Hispanic children dying in motor vehicle-related crashes, Cincinnati Children's Hospital Medical Center and Toyota today announced that they are doubling the reach of their groundbreaking safety education program Buckle Up for Life. Buckle Up for Life - or Abróchate a la Vida in Spanish - is the only national program of its kind. To view a video about the program, please click here.

9 Jul 2012

DNA from CF patients with and without chronic infections points to unsuspected mutation

Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibly. This approach discovered rare variations in the DCTN4 gene among cystic fibrosis patients most prone to early, chronic airway infections.

9 Jul 2012

Targeting double-stranded RNA dependent protein kinase could treat inflammation

Researchers at The Feinstein Institute for Medical Research have discovered that inflammation could be treated by targeting a molecule called the double-stranded RNA dependent protein kinase (PKR). These findings are published in the July issue of Nature.

9 Jul 2012

MDI and CSIRO ink tech deal for next generation production of 'Green Whistle'

Australian healthcare company Medical Developments International (MDI) and CSIRO have signed a technology deal to develop a new production process for the drug methoxyflurane - the pain-relieving ingredient used in Penthrox™ (commonly known as the green whistle).

9 Jul 2012

Medicare cuts, competing views on overhaul keep health issues hot in campaign

"Obamacare cuts Medicare - cuts Medicare - by approximately $500 billion," Mr. Romney has told audiences. That is a reprise of Republicans' mantra of the 2010 midterm elections, which gave them big gains at both the state and federal levels and a majority in the House.

8 Jul 2012

Bayer commences enrollment in BAY94-9027 Phase II/III trial for hemophilia A

Bayer HealthCare today announced the company has started to enroll patients in an international Phase II/III trial to evaluate its investigational compound BAY94-9027 for the treatment of hemophilia A.

8 Jul 2012

Conference highlights utility of zebrafish for human disorder studies

Zebrafish, popular as aquarium fish, now have an important place in research labs as a model organism for studying human diseases.

8 Jul 2012

UC Riverside receives NSF grant to address water quantity and quality issues

Water is likely to become an even more important factor in determining human well-being in the near future as the world's population continues to increase. While it is clear that the demand for water will steadily rise, it also appears that water supply could decline as a result of major shifts in the world's climate.

8 Jul 2012

Mouse model demonstrates role of AEG-1 in hepatocellular carcinoma

Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease.

8 Jul 2012

UNN, UM establish firm foundation for mutual collaborations

A delegation from the University of Nigeria (UNN) has just completed a week in key laboratories and boardrooms at the University of Maryland's Baltimore campus exploring educational exchanges between the two universities.

8 Jul 2012

Effect of spaceflight on C. elegans could help it to live longer

The effect of spaceflight on a microscopic worm - Caenorhabditis elegans (C. elegans) - could help it to live longer.

8 Jul 2012

Presence of SPDEF protein may predict prostate cancers that are unable to metastasize

Prostate cancer doesn't kill in the prostate - it's the disease's metastasis to other tissues that can be fatal. A University of Colorado Cancer Center study published this week in the Journal of Biological Chemistry shows that prostate cancer cells containing the protein SPDEF continue to grow at the same pace as their SPDEF- cousins, but that these SPDEF+ cells are unable to survive at possible sites of metastasis.

8 Jul 2012

Prominent Chinese scholars issue open letter calling for rethink of country's family planning laws

"A group of 15 prominent Chinese scholars issued an open letter on Thursday calling for a rethink of [the] country's family planning laws, arguing that the law in its present form is incompatible with China's increasing respect for human rights and need for sustainable economic development," according to the Wall Street Journal's "China Real Time Report."

7 Jul 2012

Health officials working to identify respiratory illness responsible for deaths of more than 60 Cambodian children

WHO and Cambodian health officials are investigating "the source of an unidentified illness" -- characterized by high fevers, severe respiratory problems, "and in some cases neurological symptoms" -- that has killed more than 60 children in the country since April, NPR's health blog "Shots" reports (Hensley, 7/5). "

7 Jul 2012

Dynorphin plays an important role in weakening anxiety

Feelings of anxiety very effectively prevent people from getting into situations that are too dangerous. Those who have had a terrible experience initially tend to avoid the place of tragedy out of fear. If no other oppressive situation arises, normally the symptoms of fear gradually subside.

7 Jul 2012

Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

Skin In The Game: How Consumer-Directed Plans Affect The Cost And Use Of Health Care -- Consumer-directed health plans, which feature lower premiums and higher deductibles than traditional plans, are designed to reduce costs by discouraging unnecessary care. This brief describes a study of more than 800,000 households that switched from a traditional employer-based plan to a consumer-based plan.

7 Jul 2012

SAGE sponsors symposium on cardiovascular disease prevention

European experts in cardiovascular medicine will today gather at a two day symposium to address the national agenda on cardiovascular disease prevention, held at Imperial College London and sponsored by leading independent academic and professional publisher SAGE.

7 Jul 2012

Health ministers from Southeast Asia asked to support U.N. in stemming spread of drug-resistant malaria in region

"Health ministers from the Association of Southeast Asian Nations (ASEAN) are being asked to support United Nations efforts to stem the spread of drug-resistant strains of malaria, especially along the borders of Cambodia and Burma," VOA News reports.

7 Jul 2012

Research News and Research

Merck, PDS Biotechnology enter licensing agreement for Versamune

Novel gene therapy approach may treat dysferlinopathies

Toyota, Cincinnati Children's expand Buckle Up for Life education program

DNA from CF patients with and without chronic infections points to unsuspected mutation

Targeting double-stranded RNA dependent protein kinase could treat inflammation

MDI and CSIRO ink tech deal for next generation production of 'Green Whistle'

Medicare cuts, competing views on overhaul keep health issues hot in campaign

Bayer commences enrollment in BAY94-9027 Phase II/III trial for hemophilia A

Conference highlights utility of zebrafish for human disorder studies

UC Riverside receives NSF grant to address water quantity and quality issues

Mouse model demonstrates role of AEG-1 in hepatocellular carcinoma

UNN, UM establish firm foundation for mutual collaborations

Effect of spaceflight on C. elegans could help it to live longer

Presence of SPDEF protein may predict prostate cancers that are unable to metastasize

Prominent Chinese scholars issue open letter calling for rethink of country's family planning laws

Health officials working to identify respiratory illness responsible for deaths of more than 60 Cambodian children

Dynorphin plays an important role in weakening anxiety

Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

SAGE sponsors symposium on cardiovascular disease prevention

Health ministers from Southeast Asia asked to support U.N. in stemming spread of drug-resistant malaria in region

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