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GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

3 Jul 2012

First Edition: July 3, 2012

Today's headlines include reports that continue to delve into the policy-oriented and political repercussions of last week's high court decision on the health law.

3 Jul 2012

Cells close to death from toxin exposure can survive when toxins are removed

The vast majority of cells that appear to be on a one-way track to death after exposure to toxins can bounce back completely after those toxins are removed, Johns Hopkins scientists report in a new study. The finding, published in the June 15 issue of Molecular Biology of the Cell, is not only a testament to the indomitable cellular spirit, but could also offer some practical insight on how to save dying tissues after heart attacks or strokes as well as prevent cancer in cells transiently exposed to toxins.

3 Jul 2012

Study identifies possible new approach to defeat bacterial infections

Research led by St. Jude Children's Research Hospital scientists has identified a possible new approach to defeating bacterial infections by targeting an innate immune system component in a bid to invigorate the immune response.

3 Jul 2012

Osteoarthritis susceptibility: eight potential genes discovered

The largest genome-wide association study (GWAS) of osteoarthritis to date, published Online First in The Lancet, has uncovered eight new genetic variants or loci that appear to increase susceptibility to the most common form of arthritis, which affects about 40% of the world population older than 70 years. These findings bring the total number of osteoarthritis susceptibility genes isolated in European populations to 11.

3 Jul 2012

GHTC blog reviews recent congressional actions with global health implications

In this post on the Global Health Technologies Coalition's (GHTC) "Breakthroughs" blog, GHTC Senior Policy Associate Ashley Bennett reviews recent action "on the federal budget and other pieces of legislation that could have implications for global health research and development (R&D)" and discusses "what the next several weeks could bring."

3 Jul 2012

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

Researchers are closer to understanding the biology behind GHB, a transmitter substance in the brain, best known in its synthetic form as the illegal drug fantasy. These findings have just been published in the scientific journal PNAS.

3 Jul 2012

What's ahead on the post-SCOTUS decision landscape

After the Supreme Court's decision last week upholding the health law, news outlets analyze what comes next in terms of the law's implementation, the obstacles it faces and its impact on various parts of the health system.

3 Jul 2012

$Researchers report positive effects of ibuprofen on bone repair after fracture or surgery$

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

A study conducted at the University of Granada has demonstrated that ibuprofen -a non-steroidal anti-inflammatory drug (NSAID)- has beneficial effects on bone repair after a fracture or following bone surgery.

3 Jul 2012

Obama's health law legacy still not settled; Romney faces health policy pressure

An Associated Press analysis points out that if Obama loses in November, he risks losing the law and his legacy. But Romney is also facing pressure.

3 Jul 2012

Botulinum toxin may help prevent arm tremor in people with MS

Botulinum toxin may help prevent shaking or tremor in the arms and hands of people with multiple sclerosis (MS), according to new research published in the July 3, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

3 Jul 2012

Federal judge temporarily blocks law aimed at closing Mississippi's only abortion clinic

The judge set a July 11 hearing on the state law, which would force physicians at the facility to have admitting rights at a local hospital.

3 Jul 2012

Surgeons with their own views perform quick and accurate laparoscopic procedure

What makes laparoscopic surgery "minimally invasive" - instruments enter the patient through narrow tubes - also makes it visually constraining. As they work on different tasks, surgeons all see the same view. What if each surgeon could control a separate view best suited to the specific task? In a new paper, pediatric surgeon Dr. Francois Luks and his team of co-authors at Brown University and Hasbro Children's Hospital report that in a small in vitro trial, surgeons with their own views performed faster and more accurately.

3 Jul 2012

Cutting funding for international food aid 'not the best answer' to saving money in U.S. budget

In order to "fill food gaps in the 70 most food deficient countries, ... the U.S., through the Food for Peace program and other food aid programs, provides approximately two million tons of American-grown food donations to 50 million starving people every year," James Henry, chair of USA Maritime, writes in an opinion piece in The Hill's "Congress Blog."

3 Jul 2012

Philippines to spend nearly $12M on contraceptives to bolster family planning, reduce maternal mortality rate

The government of the Philippines plans to spend nearly $12 million on contraceptives this year in an effort to "save its 'failed' family planning program and drastically cut maternal deaths," according to the Department of Health, IRIN reports.

3 Jul 2012

Bacterial vaginosis associated with increased risk of HIV transmission from women to men, study shows

Bacterial vaginosis (BV), a condition characterized by a disruption in normal vaginal bacteria, is associated with a more than three-fold increased risk of HIV transmission from an infected woman with the condition to her uninfected male partner, according to a study published June 26 in PLoS Medicine, VOA News reports.

3 Jul 2012

Viewpoints: Pressure on states to move on exchanges; Roberts' decision holds off new calls for public option

Now that the health care reform law has been ruled constitutional, it is imperative that as many states as possible move aggressively to establish a centerpiece of the reform structure: new insurance policy exchanges for people who lack affordable coverage through an employer. Federal subsidies will be available for those with low or moderate incomes.

3 Jul 2012

Research News and Research

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

First Edition: July 3, 2012

Cells close to death from toxin exposure can survive when toxins are removed

Study identifies possible new approach to defeat bacterial infections

Osteoarthritis susceptibility: eight potential genes discovered

GHTC blog reviews recent congressional actions with global health implications

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

What's ahead on the post-SCOTUS decision landscape

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

Obama's health law legacy still not settled; Romney faces health policy pressure

Botulinum toxin may help prevent arm tremor in people with MS

Federal judge temporarily blocks law aimed at closing Mississippi's only abortion clinic

Surgeons with their own views perform quick and accurate laparoscopic procedure

Cutting funding for international food aid 'not the best answer' to saving money in U.S. budget

Philippines to spend nearly $12M on contraceptives to bolster family planning, reduce maternal mortality rate

Bacterial vaginosis associated with increased risk of HIV transmission from women to men, study shows

Viewpoints: Pressure on states to move on exchanges; Roberts' decision holds off new calls for public option

Imaging PR status may help identify tumor response to endocrine therapy

Scientists discover Eya1 enzyme control of pulmonary barrier integrity

Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

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