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Artemisia plant extract prevents SARS-CoV-2 replication in vitro

A new study describes the beneficial effect of an extract of Artemisia annua when used to treat cells in culture exposed to SARS-CoV-2.

13 Sep 2021

Study identifies broadly neutralizing antibody panel against SARS-like viruses

A recent study describes 40 broadly neutralizing antibodies from two individuals with a history of COVID-19 who were recently immunized against the virus.

13 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

This study revealed that the CV3-13 antibody can mediate Fc effector functions against S protein-expressing cells.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Scientists develop a new way to grow tiny replicas of the pancreas

MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells.

13 Sep 2021

RNF5 protein plays an unusual role in acute myeloid leukemia, study shows

A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML).

13 Sep 2021

RIT study uncovers new information about how coronavirus attaches itself to human cells

Rochester Institute of Technology scientists have uncovered new information about the way coronavirus and several of its variants attach to human cells.

13 Sep 2021

Novel method enables 3D imaging of human organs with micrometer precision

Researchers at Umeå University, Sweden, now demonstrate a method by which specific cell types in human organs can be studied with micrometer precision.

13 Sep 2021

Analysis finds untapped potential for immunotherapy in older cancer patients

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

13 Sep 2021

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer's and Parkinson's.

13 Sep 2021

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

A recent study examined the ability of SARS-CoV-2 to impact DNA damage response and telomere stability in Vero E6 cells.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

Functional impairment of HIV-specific T cells precedes aborted virus control

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

CD8+ T cells - known as "killer" T cells - are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

12 Sep 2021