B Cell News and Research

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The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

The S protein has the ability to appropriate various conformations that are dependent on the formation of the receptor-binding domain (RBD) of its protomers.

12 Sep 2021

Demographic analysis of patients affected by COVID-19 in the USA

A collaborative effort aimed to determine a possible demographic explanation of COVID-19 mortality on the basis of age, sex, and ethnicity.

12 Sep 2021

Lung cancer patients report high anxiety levels and experience treatment delays due to the pandemic

Patients coping with lung cancer and treated in one hospital in Mexico reported high levels of anxiety and saw their treatment delayed or due to the COVID-19 pandemic, according to a study presented today at the IASLC World Conference on Lung Cancer.

12 Sep 2021

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

A study presented today at the IASLC 2021 World Conference on Lung Cancer suggests how oncology practices in the United States changed after 2018, when durvalumab became available for patients with unresectable Stage III non-small cell lung cancer.

12 Sep 2021

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

A clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer.

12 Sep 2021

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

Treatment with atezolizumab plus carboplatin and pemetrexed was safe and yielded promising brain progression-free survival in patients with nonsquamous non-small cell lung cancer with untreated and asymptomatic brain metastases.

12 Sep 2021

Study reveals blood metabolites associated with dementia

Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia.

12 Sep 2021

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell.

12 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Researchers identify mechanism behind structural birth defects in fetuses of mothers with diabetes

More than 3 million women of birthing age in the U.S. and 60 million in the world have diabetes - a disease that occurs when blood sugar is too high.

10 Sep 2021

Study identifies FDA-approved drugs that are effective in suppressing SARS-CoV-2 replication

Despite the development of SARS-CoV-2 vaccines, effective therapeutics are needed until worldwide immunity has been achieved.

10 Sep 2021

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

A review aimed to determine the potential of siRNA as a potential COVID-19 treatment by reviewing the currently available literature.

10 Sep 2021

Cryopreservation Excipient for Cell Therapies

AMSBIO has launched STEM-CELLBANKER® EX - a next generation cryopreservation product that eliminates the need for the traditional washing steps required in cell therapy product development.

From AMS Biotechnology 10 Sep 2021

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

A group of researchers analyzed the B cell response to SARS-CoV-2 in unexposed individuals.

10 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Sequencing the human genome - a feat accomplished in 2003 - provided the list of ingredients that make up a human being, but not the instructions that explain how those ingredients are used by each cell type to create complex "meals."

9 Sep 2021

Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.

9 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

B Cell News and Research

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

Demographic analysis of patients affected by COVID-19 in the USA

Lung cancer patients report high anxiety levels and experience treatment delays due to the pandemic

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

Study reveals blood metabolites associated with dementia

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

NIH researchers develop a detailed cellular map of chronic MS lesions

Researchers identify mechanism behind structural birth defects in fetuses of mothers with diabetes

Study identifies FDA-approved drugs that are effective in suppressing SARS-CoV-2 replication

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

Cryopreservation Excipient for Cell Therapies

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Enzyme appears to be a major driver of dangerous pregnancy complication

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Physical exercise can improve cancer-induced anemia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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