Receptor News and Research

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Publication of epilepsy research

Bionomics Limited has announced today that research by its collaborators Women's and Children's Hospital, in conjunction with the University of Melbourne and a US group in Tennessee, has been published in the scientific journal, Human Molecular Genetics.

13 May 2004

Leading experts to shed light on controversial testosterone therapy treatment

The use of testosterone therapy will be the topic of a special panel briefing to be held during the 99th Annual Scientific Meeting of the American Urological Association on May 11, 2004 in the Moscone Center in San Francisco.

12 May 2004

Small, frequent doses of caffeine best strategy for staying awake

Caffeine is the world's most widely-used stimulant yet, scientists still do not know exactly how it staves off sleep. Researchers at Brigham and Women's Hospital, Harvard Medical School and other institutions have now discovered that caffeine works by thwarting one of two interacting physiological systems that govern the human sleep-wake cycle.

11 May 2004

Strategy to treat obesity through molecular liposuction

Researchers at The University of Texas M. D. Anderson Cancer Center have designed a strategy to treat obesity through “molecular liposuction.” The therapy destroys blood vessels supporting fat accumulation — causing the fat to rapidly break down and disappear.

10 May 2004

New studies on the diagnosis of interstitial cystitis and the treatment of prostatitis

Antimicrobials Ineffective in Treating Chronic Prostatitis / Pelvic Pain Syndrome (CP/PPS): Though the traditional means of treating men with CP/PPS, use of antibiotics and alpha-adrenergic receptor blockers (tamsulosin and ciprofloxacin) did not lead to significant change after six and 12 weeks of treatment.

10 May 2004

Afro-Americans with high blood pressure have double the risk of enlarged heart

American blacks with high blood pressure have nearly double the risk for left ventricular hypertrophy (enlarged heart) compared to hypertensive whites, researchers report in today’s rapid access issue of Hypertension: Journal of the American Heart Association.

6 May 2004

A second-generation targetted antibody for potential cancer therapy

The overproduction, or 'overexpression', of the epidermal growth factor receptor (EGFR) is one of the most common aberrations in cancer, and subsequently agents that inhibit EGFR are among the most hotly-pursued potential products in the pharmaceutical industry.

6 May 2004

Trial of antibody for HIV Infection

Tanox, Inc. announced today that it has begun dosing patients in its Phase 2 clinical trial of TNX-355 for the treatment of the human immunodeficiency virus (HIV).

5 May 2004

Gene therapy helps alcoholic rats

As a follow up to previous work showing that gene therapy can reduce drinking in rats trained to prefer alcohol, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have used the same technique to cut drinking in rats with a genetic predisposition for heavy alcohol consumption.

5 May 2004

Morphine does not alleviate acute pain in preterm neonates

Preterm neonates undergo many painful procedures as part of their standard care in the Neonatal Intensive Care Unit (NICU). Preterm babies are able to experience pain and indeed are highly sensitive to it.

2 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

Increased blood levels of a heart cell “stress” protein called ST2 were linked to a higher risk of death

Increased blood levels of a heart cell “stress” protein called ST2 were linked to a higher risk of death and congestive heart failure in the 30 days after a heart attack, researchers report in today’s rapid access issue of Circulation: Journal of the American Heart Association.

29 Apr 2004

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Mutation of a gene involved in non-small cell lung cancer (NSCLC) increases the likelihood that the drug gefitinib (Iressa™) will show a beneficial response, researchers at the Dana-Farber Cancer Institute, the National Cancer Institute (NCI) - part of the National Institutes of Health - and two other institutions announced today in the online version of Science.

29 Apr 2004

Bypass surgery results in better five-year survival than balloon angioplasty and stent procedures

Bypass surgery results in better five-year survival than balloon angioplasty and stent procedures for patients with serious coronary artery disease and additional health conditions such as diabetes

28 Apr 2004

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Researchers at Duke University have developed a new analytical approach that combines genetic and clinical data to give cancer patients an individualized prognosis of their cancer recurrence. The information could prove critical in deciding how aggressively to treat the disease following surgery.

26 Apr 2004

Oxford researchers find possible new type of antibiotic

Dr Ben Davis in the Department of Chemistry at Oxford University, England and his collaborators have discovered a possible new route to antibiotics.

26 Apr 2004

Possible breakthrough in AIDS and cancer research

Mayo Clinic researchers have found a way to revive immunity in mice that have abnormal or deficient immune systems. The discovery may lead to a means of restoring immunity to individuals with immunodeficiency diseases such as AIDS and cancer.

20 Apr 2004

New research findings about T-cell transport shed light on immune system

New research findings about T-cell transport shed light on how the normal immune system functions and could have implications in fighting autoimmune and inflammatory diseases, say researchers at University of Texas Southwestern Medical Center, Dallas.

20 Apr 2004

Myriad Genetics advances drug for chemotherapy-induced nausea

Myriad Genetics, Inc. today released new data on MPC-4505, its Neurokinin-1 (NK1) receptor antagonist, a drug candidate for chemotherapy-induced nausea and vomiting (emesis). MPC-4505 is a potent, orally bioavailable, CNS-penetrating, highly selective NK1 antagonist.

20 Apr 2004

Estrogen–like drugs may help postmenopausal women

Scientists may debate whether weight gain is a side effect of menopause, but the numbers are clear: On average, women may experience a gain of approximately 10-15 pounds in the years surrounding menopause.

19 Apr 2004