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Selenium reduces Staph populations in medical implants

Selenium is an inexpensive element that naturally belongs in the body. It is also known to combat bacteria. Still, it had not been tried as an antibiotic coating on a medical device material. In a new study, Brown University engineers report that when they used selenium nanoparticles to coat polycarbonate, the material of catheters and endotracheal tubes, the results were significant reductions in cultured populations of Staphylococcus aureus bacteria, sometimes by as much as 90 percent.

22 Jun 2012

Study: Unexpected activity of estrogenic compounds during early stages of embryonic development

Chemicals in the environment that mimic estrogen can strongly influence the development of humans and other animals. New research to be presented at the 2012 International Zebrafish Development and Genetics Conference, held June 20-24 in Madison, Wisconsin, reveals that these substances may act even earlier than previously realized, at the very beginning stages of embryonic development.

22 Jun 2012

Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma

Aeterna Zentaris Inc. today announced that Phase 1 trial results for its oral PI3K/Akt inhibitor, perifosine, showed the drug's activity against chemo-resistant and radio-resistant neuroblastoma, while allowing good quality of life and sparing vital organs. Neuroblastoma is a type of childhood cancer which usually begins in nerve tissues.

22 Jun 2012

Political jockeying accelerates in anticipation of decision

News outlets report on how political leaders, interest groups and the presidential campaigns have stepped up their messaging strategies surrounding the long-awaited Supreme Court ruling.

22 Jun 2012

Iroko announces results from diclofenac Phase 3 study on post-surgical pain

Iroko Pharmaceuticals, LLC today announced Phase 3 study results that showed patients treated with the company's novel, submicron particle, lower-dose diclofenac (18mg and 35mg), a non-steroidal anti-inflammatory drug (NSAID), experienced significant pain relief post surgery compared with placebo>0.01 and P<0.001 respectively).

22 Jun 2012

Report: Autoimmune diseases are all being diagnosed at rapid rates

There is a disturbing trend in autoimmune disease diagnosis; many are on the upswing. Recent reports show that type 1 diabetes (an autoimmune disease not related to obesity), celiac disease and lupus, among others autoimmune diseases, are all being diagnosed at rapid rates.

22 Jun 2012

U.S. Senate Foreign Relations Committee passes Senator Paul Simon Water for the World Act

"In an exciting move for the water, sanitation and hygiene (WASH) community, the U.S. Senate Foreign Relations Committee passed the Senator Paul Simon Water for the World Act of 2011 (S 641), bringing the bill one step closer to becoming a law," PSI's "Healthy Lives" blog reports.

22 Jun 2012

DBS can improve muscle symptoms in patients with Parkinson's

Patients with Parkinson's disease who undergo deep brain stimulation (DBS)—a treatment in which a pacemaker-like device sends pulses to electrodes implanted in the brain—can expect stable improvement in muscle symptoms for at least three years, according to a Department of Veterans Affairs study appearing in the most recent issue of the journal Neurology.

22 Jun 2012

Polio eradication efforts threatened by funding shortfall, vaccination resistance in some countries, experts say

Marking the 10th anniversary since Europe was declared polio-free, the Independent Monitoring Board (IMB) of the Global Polio Eradication Initiative on Wednesday released a report saying there is "a unique window of opportunity to stamp out polio for good," with the number of reported cases at historical lows, but a funding shortfall of about $1 million is threatening eradication progress, Reuters reports.

22 Jun 2012

IU receives CMS grant to expand Aging Brain Care model

A $7.8 million Health Care Innovation Award to Indiana University from the Centers for Medicare & Medicaid Services (CMS), will expand the Aging Brain Care model developed by researcher-clinicians from the IU Center for Aging Research and the Regenstrief Institute.

22 Jun 2012

Lead 8A analog can treat osteosarcoma in children

Jiayuh Lin, PhD, and colleagues at Nationwide Children's Hospital have developed a drug to target the most common cancerous bone tumor in children, osteosarcoma, using a version of the FDA-approved drug, Celebrex. The team will soon begin testing the drug using human and canine tumor cell lines thanks to a two-year, $200,000 grant from Alex's Lemonade Stand Foundation for Childhood Cancer.

22 Jun 2012

GlobalPost examines investment in community care workers in South Africa as PEPFAR moves toward local implementation of programming

"Nearly a decade after it came into being, the President's Emergency Plan for AIDS Relief (PEPFAR) ... is moving increasingly to support local leadership and implementation capacity" in South Africa, GlobalPost's "Global Pulse" blog reports.

22 Jun 2012

CDSS best for assessing depression symptoms in schizophrenia

Results from a systematic review of published studies suggests that the Calgary Depression Scale for Schizophrenia is the most reliable and valid instrument for assessing depression symptoms in patients with schizophrenia.

21 Jun 2012

Cognitive function worse in pediatric BD I than II

Children with bipolar I disorder have significantly poorer cognitive functioning than those with bipolar II disorder, research shows.

21 Jun 2012

Connexin 43 deficiency may protect against bed rest-associated bone loss

Mice lacking connexin 43, the most abundant gap junction protein in bone, have a decreased susceptibility to the effects of mechanical unloading on bone, US researchers report.

21 Jun 2012

$Hip fracture type may determine regional anesthesia benefits$

Hip fracture type may determine regional anesthesia benefits

Use of regional anesthesia may reduce the risk for mortality and pulmonary complications among patients undergoing surgery for hip fracture, research shows.

21 Jun 2012

Proper exsanguinator and tourniquet use poorly understood

Operating theater personnel have a poor understanding of appropriate exsanguinator and tourniquet use, show research results from a hospital in Ireland.

21 Jun 2012

New issue of 'Global Fund News Flash' available

The Global Fund to Fight AIDS, Tuberculosis and Malaria on Tuesday released Issue 4 of its newsletter, the "Global Fund News Flash." The issue features a commentary by Mireille Guigaz, a Global Fund Board member representing France, on the Global Fund's work in Madagascar, and a piece examining "a Board decision last November that 55 percent of all funding for grant renewals should go to low-income countries," among other stories.

21 Jun 2012

Winners and losers in the health care messaging war

The Pew Research Center's Project for Excellence in Journalism says that opponents of the health law prevailed at least in part because their positions were sharper and easier to understand.

21 Jun 2012

CRN releases 'The Benefits of Nutritional Supplements'

The Council for Responsible Nutrition (CRN), the dietary supplement industry's leading trade association, today released its comprehensive report, The Benefits of Nutritional Supplements.

21 Jun 2012