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Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

As part of its "Life?" project, the Volkswagen Foundation is funding a research project that is placing membraneless organelles within cells in the spotlight as a way of understanding the fundamental processes that are essential to life.

6 Sep 2021

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

6 Sep 2021

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

More than 40 million people worldwide are affected with type 1 diabetes (T1D) mellitus, an autoimmune disease in which insulin producing β-cells in the pancreas are destroyed by the immune system.

6 Sep 2021

Increased infectivity and immune evasion drive the spread of Delta SARS-CoV-2 variant

Findings suggest infection control measures against variants will need to continue in the post-vaccination era.

6 Sep 2021

New insights could help unlock the mystery of how lung cancer arises in never smokers

A genomic analysis of lung cancer in people with no history of smoking has found that a majority of these tumors arise from the accumulation of mutations caused by natural processes in the body.

6 Sep 2021

Prognostic impact of common type of liver cancer depends on tumor size, research reveals

Researchers at the Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine have shown that the prognostic impact of hepatocellular carcinoma (HCC), the most common type of liver cancer, is dependent on tumor size.

6 Sep 2021

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Oncotarget published "Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells" which reported that this assay is based on the use of two isogenic HT1080 cell lines, one carrying a linear HAC and the other carrying a circular HAC.

6 Sep 2021

Is the SARS-CoV-2 Lambda variant more vaccine-resistant than the Delta variant?

Researchers in the USA and China recently published a report in which they discussed the potential factors that confer high infectivity and immune resistance on the Delta and Lambda variants.

6 Sep 2021

Post-exposure prophylaxis with monoclonal antibodies may reduce health system burden in the US

In a study conducted at the University of Washington, USA, the researchers assert that post-exposure prophylaxis with monoclonal antibodies could improve the clinical outcomes and health system costs regarding coronavirus disease (COVID-19). The study is currently available on the medRxiv* preprint server.

6 Sep 2021

SARS-CoV-2 fusion peptides play distinct roles according to neutron scattering

A new study determines the physical and thermodynamic events associated with the interactions that lead to the fusion between SARS-CoV-2 and the host.

5 Sep 2021

Efficacy of vaccines against the SARS-CoV-2 Delta variant

A new study uses statistical models to determine vaccine efficacy against the various SARS-CoV-2 variants and clinical endpoints for SARS-CoV-2 variants.

5 Sep 2021

Researchers develop the smallest CRISPR to date for genome editing

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell.

4 Sep 2021

Chief medical officers to consider vaccination of 12 to 15 year olds from a broader perspective

The four Chief Medical Officers will provide further advice on the COVID-19 vaccination of young people aged 12 to 15 with COVID-19 vaccines following the advice of the independent Joint Committee on Vaccination and Immunisation.

4 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021

Temperature variations could have driven the division of protocells

A simple mechanism could underlie the growth and self-replication of protocells - putative ancestors of modern living cells - suggests a study publishing September 3 in Biophysical Journal.

4 Sep 2021

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he thinks it's time to reimagine CRISPR as a Swiss Army knife.

4 Sep 2021

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

4 Sep 2021

Weill Cornell receives NIH support to advance TB research

Tuberculosis (TB) is one of the deadliest infectious diseases in history and one of the few that naturally infects only humans.

4 Sep 2021

Immunological differences in Moderna and Pfizer-BioNTech vaccine-induced Fc-functional profiles

A new study analyzed the post-boost binding and functional capacity of the humoral response induced by the Pfizer-BioNTech and Moderna vaccines.

3 Sep 2021

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Oncotarget published "JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA" which reported that the effects of low and high concentrations of arecoline on the stability of tight junctions and EMT induction were studied.

3 Sep 2021

B Cell News and Research

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

Increased infectivity and immune evasion drive the spread of Delta SARS-CoV-2 variant

New insights could help unlock the mystery of how lung cancer arises in never smokers

Prognostic impact of common type of liver cancer depends on tumor size, research reveals

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Is the SARS-CoV-2 Lambda variant more vaccine-resistant than the Delta variant?

Post-exposure prophylaxis with monoclonal antibodies may reduce health system burden in the US

SARS-CoV-2 fusion peptides play distinct roles according to neutron scattering

Efficacy of vaccines against the SARS-CoV-2 Delta variant

Researchers develop the smallest CRISPR to date for genome editing

Chief medical officers to consider vaccination of 12 to 15 year olds from a broader perspective

Scientists identify a critical checkpoint in transcription elongation

Temperature variations could have driven the division of protocells

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Weill Cornell receives NIH support to advance TB research

Immunological differences in Moderna and Pfizer-BioNTech vaccine-induced Fc-functional profiles

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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