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Researchers identify cells responsible for cardiac damage repair after infarction

Researchers at Cima and the Clinica Universidad de Navarra (Spain) have led an international study identifying the cardiac cells responsible for repairing the damage to this organ after infarction.

29 Sep 2020

Computer model unravels mystery behind severe inflammation in people with COVID-19

A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation?

29 Sep 2020

Researchers develop a new substance that can disarm tumor-promoting proteins

The villain in this drama has a pretty name: Aurora - Latin for dawn. In the world of biochemistry, however, Aurora (more precisely: Aurora-A kinase) stands for a protein that causes extensive damage. There, it has been known for a long time that Aurora often causes cancer.

29 Sep 2020

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

A special issue on the emerging COVID-19 infection

Acta Pharmaceutica Sinica B publishes special issue on 'Research on Emerging COVID-19 (Target, Mechanism, and Therapeutics)' edited by Hai-Bin Luo, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China; Shilin Chen, Institute of Chinese Materia Medica, Beijing, China and Peiqing Liu, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.

29 Sep 2020

Study shows how Zika virus degrades key protein involved in neurological growth

In a study published in Autophagy, researchers at the University of Maryland (UMD) shed new light on how Zika virus hijacks our own cellular machinery to break down a protein that is essential for neurological development and cellular communication, getting it to "eat itself."

29 Sep 2020

MU researchers identify mutations in virus causing COVID-19

When Saathvik Kannan's father, a faculty member at the University of Missouri, saw his friend, Kamlendra Singh, a research professor at MU, on television being interviewed for his research identifying possible treatments for COVID-19, he called Singh to congratulate him on his work.

29 Sep 2020

Study unravels how lysosomal damage response pathways prevent kidney injury

Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of.

28 Sep 2020

SARS-CoV-2 re-infection is real but rare: Case study

Now, American researchers have looked at all reported cases of re-infection and the possible reasons behind them. Their study titled, “Re-infection with SARS-CoV-2 and Failure of Humoral Immunity: a case report,” is published online on the preprint server medRxiv in September 2020.

28 Sep 2020

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD).

28 Sep 2020

Healthy vitamin D levels could reduce COVID-19 complications

Published in the journal PLOS ONE, the study investigates the link between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes and parameters of immune function and mortality due to COVID-19.

28 Sep 2020

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

A multicenter phase 1/2a randomized, double-blinded, placebo-controlled clinical trial has been conducted recently to evaluate the safety, reactogenicity, and immunogenicity of a non-replicating adenovirus-based vaccine, namely Ad26.COV2.S against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection.

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

Several months into the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we still do not know much about the early evolutionary history and order of mutational events of the virus during this pandemic.

28 Sep 2020

New mechanism that prevents hair loss identified

A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair loss: hair follicle stem cells, essential for hair to regrow, can prolong their life by switching their metabolic state in response to low oxygen concentration in the tissue.

28 Sep 2020

Protein C News and Research

Researchers identify cells responsible for cardiac damage repair after infarction

Computer model unravels mystery behind severe inflammation in people with COVID-19

Researchers develop a new substance that can disarm tumor-promoting proteins

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

A special issue on the emerging COVID-19 infection

Study shows how Zika virus degrades key protein involved in neurological growth

MU researchers identify mutations in virus causing COVID-19

Study unravels how lysosomal damage response pathways prevent kidney injury

SARS-CoV-2 re-infection is real but rare: Case study

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Healthy vitamin D levels could reduce COVID-19 complications

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Scientists identify a new way to regulate cell plasticity

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

New mechanism that prevents hair loss identified

Early introduction of gluten may be an effective celiac disease prevention strategy

Interdisciplinary team wins NIH grant to develop a device for early oral cancer detection

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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