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Normal p53 gene makes breast cancer chemotherapy with doxorubicin less effective

Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published today in the journal Cancer Cell.

12 Jun 2012

New data on individuals with natural ability to fight off AIDS

"Scientists on Sunday said they had found a key piece in the puzzle as to why a tiny minority of individuals infected with HIV have a natural ability to fight off the deadly AIDS virus," Agence France-Presse reports.

12 Jun 2012

Scientists establish link between autoimmune diseases and nanoparticles

New groundbreaking research by scientists at Trinity College Dublin has found that exposure to nanoparticles can have a serious impact on health, linking it to rheumatoid arthritis and the development of other serious autoimmune diseases.

12 Jun 2012

GlobalPost reports on Cuba's medical outreach to Africa

GlobalPost reports on Cuba's medical outreach to Africa, writing, "A generation ago, Fidel Castro sent Cuban soldiers to intervene in African civil conflicts and fight the Cold War against U.S. proxies. Now, Cuba's doctors are fanning out across the continent as the island expands its role in administering medical services to some of the world's most ailing countries."

12 Jun 2012

Researchers identify two proteins that are required to maintain kidney stem cells

Studying mice and humans, researchers at Washington University School of Medicine in St. Louis and their collaborators in Paris have identified two proteins that are required to maintain a supply of stem cells in the developing kidney.

12 Jun 2012

Researchers find pathway for origin and growth of the most common form of brain and spinal cord tumor – meningioma

Johns Hopkins researchers say they have discovered one of the most important cellular mechanisms driving the growth and progression of meningioma, the most common form of brain and spinal cord tumor.

12 Jun 2012

Main causes of unprofessional behavior among hospitalists revealed

Unprofessional behavior among hospitalists is rare, but those who do behave poorly share common features, according to research published in the Journal of Hospital Medicine.

12 Jun 2012

Uncertainty over efficacy of clopidogrel in hemolytic uremic syndrome

Clinical outcomes for children hospitalized with diarrhea-associated hemolytic uremic syndrome are comparable between those treated with clopidogrel and those who are not, show study findings.

12 Jun 2012

NMDA antibodies increased in mania patients

Patients with bipolar disorder show increased levels of antibodies to the NR2 subunits of the N-methyl-D-aspartate receptor during periods of acute mania, researchers report.

12 Jun 2012

Stress troubles women’s hearts

Women experience more myocardial stress than men, regardless of arterial hemodynamic function and cardiac geometry and output, research shows.

12 Jun 2012

Key dynamics in play in long-awaited health law decision

News outlets report on the key issues and underlying statutes that might shape the Supreme Court's upcoming ruling on the health law, and how stakeholders and politicians are planning their next steps.

12 Jun 2012

DNDi, Astellas partner on new drug discovery research for treatment of NTDs

Astellas Pharma Inc. and the Drugs for Neglected Diseases initiative (DNDi) announced an agreement today to collaborate on drug discovery research for leishmaniasis, Chagas disease, and sleeping sickness - three neglected tropical diseases (NTDs) which together affect nearly 10 million people worldwide.

12 Jun 2012

Organized rallies around U.S. decry contraception coverage mandate

More than 100 organized rallies in states around the nation this weekend decried the Obama administration decision to require insurers and employers to cover contraception in their health plans as an attack on their religious freedom.

12 Jun 2012

Study reveals mystery of how pancreatic cancer escapes immune detection

Researchers at NYU School of Medicine have made a key discovery that could help doctors treat one of the deadliest cancers.

12 Jun 2012

Medicaid: Managed care contracts, copay proposals make state news

State Medicaid programs -- including both managed care contracts and new copay proposals -- are making news in Ohio, California, Florida and Arizona.

12 Jun 2012

Smoking may increase risk of death in older patients

An analysis of available medical literature suggests smoking was linked to increased mortality in older patients and that smoking cessation was associated with reduced mortality at an older age, according to a report published in the June 11 issue of Archives of Internal Medicine, a JAMA Network publication.

12 Jun 2012

GlobalPost launches new special reporting series on fight against AIDS

GlobalPost on Monday launched a new special reporting series called "AIDS: A Turning Point," according to an email alert from the new service. "In the lead up to July's International AIDS Conference in Washington -- the first such conference on U.S. soil in 22 years -- the world news site GlobalPost presents a deep look at both the global struggle to reduce HIV infection rates as well as some surprising lessons on the effective approaches that Southern Africa has to teach America," the email alert reports.

12 Jun 2012

Presidential campaigns jockey for support from seniors, Hispanic voters

Press reports detail how both the Romney and Obama campaigns are taking steps to attract these voting blocs.

12 Jun 2012

ST Blood & Tissue Center, Saneron sign clinical supply and research collaboration agreement

Saneron CCEL Therapeutics, Inc. of Tampa, Florida, and South Texas Blood & Tissue Center of San Antonio, have signed a clinical supply and research collaboration agreement. Under the agreement, the South Texas Blood & Tissue Center will research approaches for recovering and processing proprietary mononuclear cells from umbilical cord blood.

12 Jun 2012

Cellular source of cervical cancer found

A team of scientists from A*STAR's Institute of Medical Biology (IMB) and Genome Institute of Singapore (GIS) together with clinicians from Boston's Brigham and Women's Hospital (BWH) have identified a unique set of cells in the cervix that are the cause of human papillomaviruses (HPV) related cervical cancers. Significantly, the team also showed that these cells do not regenerate when excised.

12 Jun 2012