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Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Researchers find an abundance of microplastics in placentas and meconium samples

The embryonic and fetal periods of life are vulnerable to impact by harmful chemicals in the environment. These include microplastics (MPs), which have been found in many living organisms and tissues, stemming from the environmental degradation of waste plastics. Using placental tissue and meconium samples, a new study examines the links between exposure to MPs in pregnancy and microbiomes.

21 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

Tumor matrix profiles determine the risk and prognosis of a common type of lung cancer

Scientists at the Garvan Institute of Medical Research have identified molecular profiles of the surrounding matrix of a common type of lung cancer that might indicate which patients are likely to develop aggressive tumors.

21 Nov 2022

MRI reveals brain changes in patients up to six months after COVID-19 recovery

Using a special type of MRI, researchers have uncovered brain changes in patients up to six months after they recovered from COVID-19, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

New therapeutic windows for developing effective treatments for metastatic tumors

Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers at Chalmers University of Technology, Sweden, have shown that these metastatic cancers, that spread from the original, adapt their metabolism to the tissue in which they grow. The discovery represents a breakthrough for the understanding of metastatic cancer and is an important piece of the puzzle in the search for more effective treatments.

17 Nov 2022

Study reveals novel therapeutic targets for airway relaxation

Bronchial constriction is what makes many lung diseases like asthma so dangerous. Researchers have discovered a new signaling pathway that causes the airways to widen.

17 Nov 2022

Experts investigate the role of IL-26 in COVID-19

Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory response that signifies severe cases of the disease. The findings, which are presented in Frontiers in Immunology, indicate that IL-26 is a potential biomarker for severe COVID-19.

17 Nov 2022

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Researchers from the Centenary Institute and the University of Sydney have developed a new nasal vaccination strategy that induces potent lung immunity and protection against the SARS-CoV-2 coronavirus.

16 Nov 2022

Smoking marijuana damages the lungs more than tobacco

Lungs of marijuana smokers exhibit greater levels of airway inflammatory markers and emphysema as compared to those of tobacco-only smokers.

15 Nov 2022

Study finds higher rate of emphysema and airway diseases among marijuana smokers

Researchers from the University of Ottawa and The Ottawa Hospital have found marijuana smokers have a higher rate of emphysema and airway diseases compared to cigarette smokers.

15 Nov 2022

Emphysema rates higher among marijuana smokers than cigarette smokers

Airway inflammation and emphysema are more common in marijuana smokers than cigarette smokers, according to a study published in Radiology, a journal of the Radiological Society of North America.

15 Nov 2022

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers discuss the beneficial role of polyphenolic plant compounds in the Mediterranean diet in the prevention and treatment of COVID-19.

15 Nov 2022

Early mobility contributes to higher survival rates for COVID-19 patients receiving ECMO

A Texas cardiac subspecialty hospital with seven years of experience with extracorporeal membrane oxygenation (ECMO) changed its treatment paradigm during the COVID-19 pandemic, finding that progressive mobility and a more aggressive application of rehabilitation therapies contributed to significantly higher survival rates for its patients with COVID-19 receiving ECMO.

15 Nov 2022

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

A recent study reported that helminth exposure enhances viral clearance and survival of mice challenged with SARS-CoV-2.

15 Nov 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

High-intensity aerobic exercise can cut metastatic cancer risk by 72%

A new study at Tel Aviv University found that aerobic exercise can reduce the risk of metastatic cancer by 72%.

14 Nov 2022

Lungs News and Research

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Researchers find an abundance of microplastics in placentas and meconium samples

Kiwira virus: a new bat-borne hantavirus detected in Africa

Tumor matrix profiles determine the risk and prognosis of a common type of lung cancer

MRI reveals brain changes in patients up to six months after COVID-19 recovery

Study suggests bats are an underrecognized arenavirus reservoir

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

New therapeutic windows for developing effective treatments for metastatic tumors

Study reveals novel therapeutic targets for airway relaxation

Experts investigate the role of IL-26 in COVID-19

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Smoking marijuana damages the lungs more than tobacco

Study finds higher rate of emphysema and airway diseases among marijuana smokers

Emphysema rates higher among marijuana smokers than cigarette smokers

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Early mobility contributes to higher survival rates for COVID-19 patients receiving ECMO

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

PALS program effective in ensuring diverse representation in lupus clinical trials

Novel drug could help to fight both COVID-19 and cancer

High-intensity aerobic exercise can cut metastatic cancer risk by 72%

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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