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Ear's tiny outer hair cells regulate sound sensitivity, study shows

The ear’s tiny outer hair cells adjust the sensitivity of neighboring inner hair cells to sound levels rather than acting like an amplifier, suggests a new study published today in eLife.

24 Sep 2019

Study identifies factor essential for tendon growth

Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery.

24 Sep 2019

Bath researchers identify promising prostate cancer drug candidates

Cancer researchers from the University of Bath have identified some promising drug candidates by using high-throughput screening methods to test tens of thousands of molecules.

24 Sep 2019

Study uncovers epigenetic origins for hypersexual disorder

A new study has shown that epigenetic changes lead to overactivity of the hormone oxytocin, and this is a key element in hypersexual disorder.

24 Sep 2019

Researchers make breakthrough in understanding enzymes that assemble the antibiotic enacyloxin

One of the WHO's three critical priority pathogens, Acinetobacter baumannii, for which new antibiotics are urgently needed is one step closer to being tackled, as researchers from the Department of Chemistry - University of Warwick have made a breakthrough in understanding the enzymes that assemble the antibiotic enacyloxin.

24 Sep 2019

Study: Certain genes that predict risk of high cholesterol differ between countries

Some of the genes that predict the risk of high cholesterol don't apply to people from Uganda the same as they do in European populations, finds a new UCL-led study.

24 Sep 2019

As off-label use spreads, supplies of niche drugs and patients’ patience grow short

Medical treatment has knocked down tumors in 6-year-old Easton Daniels' brain, but the drug used also wiped out his immune system.

24 Sep 2019

Delivery of drugs within the brain can be improved by utilizing LAT1

According to a new study carried out at the University of Eastern Finland, the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain.

24 Sep 2019

Penn State scientists receive AHA grant, propose new way to prevent thrombosis

Two Penn State biomedical engineering faculty members have received a two-year, $200,000 grant from the American Heart Association (AHA) to explore potential solutions to thrombosis, or blood clot formation, a prevalent issue with blood-contacting medical devices such as heart valves, blood pumps and cardiac stents.

24 Sep 2019

New microcapsules provide safe and effective delivery of drugs, biomolecules

Cracking an egg to release its yolk requires applying external force (like being smacked against the edge of a bowl) to overcome the strength of the eggshell.

24 Sep 2019

New drug delivery system could be a boon for those on a multi-drug regimen

Researchers from the University of North Carolina at Chapel Hill have developed a unique new multi-drug delivery system that could p-rove to be useful for persons who need to take several drugs in a day as part of a regimen.

23 Sep 2019

Unexpected mechanism of action found with sertraline

A new study on sertraline, which is one of the most popular drugs for depression and anxiety, shows that its efficacy is undoubted, but it operates primarily by reducing anxiety rather than depression.

23 Sep 2019

New discovery may revolutionize treatment of drug-resistant epilepsy

Researchers at Carnegie Mellon University have discovered that the spreading of seizures through the brain can be suppressed depending on the amount of pressure within the brain, an important discovery that may revolutionize the treatment of drug-resistant epilepsy.

23 Sep 2019

Wake Forest Baptist receives multimillion-dollar grant for innovative cancer care research

For the second time in five years, Wake Forest Baptist Health has been recognized for its expertise in conducting innovative cancer care research by the National Cancer Institute's Community Oncology Research Program with a multimillion-dollar grant.

23 Sep 2019

Synthetic oral cannabinoid use found to be more common among older adults with COPD

A study published today in Drugs & Aging found that older adults in Ontario with chronic obstructive pulmonary disease were twice as likely to use prescription synthetic oral cannabinoids compared to older adults without COPD.

23 Sep 2019

New study shows how fungal biofilm morphology impacts lung disease

Findings from an innovative new study led by researchers at Dartmouth's Geisel School of Medicine and published this week in Nature Microbiology reveal that the way in which human fungal pathogens form colonies can significantly impact their ability to cause disease.

23 Sep 2019

Light-activated metal compound cuts off cancer cell's 'power source'

A space-age metal that formed part of the asteroid that destroyed the dinosaurs could provide a new method of treating cancer tumors selectively using light.

23 Sep 2019

MRI shown to be a powerful tool in the detection and prevention of minor stroke

Recently, researchers discovered that strokes in low risk patients could be predicted and potentially even prevented using MRI.

23 Sep 2019

Fullerene compounds effectively combat dangerous viral infections

Scientists from the Skoltech Center for Energy Science and Technology and the Institute of Problems of Chemical Physics of RAS in collaboration with researchers from four other Russian and foreign research centers have discovered a new reaction that helps obtain water-soluble fullerene derivatives which effectively combat flu viruses, human immunodeficiency virus, herpes simplex virus, and cytomegalovirus.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019