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New experiments reveal how viruses initiate translation of genetic material into proteins

Infectious viruses come in many shapes and sizes and use slightly different attack mechanisms to make humans and animals sick.

25 Sep 2020

Human-to-cat transmission of SARS-CoV-2 confirmed

Cat-to-cat transmission of SARS-CoV-2 has been experimentally proven, but little is known about the significance of this novel virus as a feline pathogen or its reverse zoonotic potential. The establishment of new animal reservoirs of SARS-CoV-2 could pose serious problems for human health in the future.

24 Sep 2020

UNH awarded $1.8 million NIH grant to advance molecular research in diabetes and cancer

The University of New Hampshire will receive $1.8 million from the National Institutes of Health that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.

24 Sep 2020

Two studies shed light on the biology and potential vulnerabilities of schistosomes

Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes - parasitic flatworms that cause the little-known tropical disease schistosomiasis.

24 Sep 2020

Linoleic acid binds SARS-CoV-2 spike protein

Now, a team of researchers at the Max Planck-Bristol Center for Minimal Biology and Bristol's School of Biochemistry has identified a druggable pocket in the virus's spike protein that can be used to prevent the infection of cells. The study findings, published in the journal Science, are a groundbreaking discovery that will help develop new therapies and drugs to stem the growing pandemic.

24 Sep 2020

Research sheds light on how membrane proteins could be influenced by lipid environments

The cell membrane, the wall-like boundary between the cell interior and its outside environment, is primarily made up of two kinds of biomolecules: lipids and proteins. Different

24 Sep 2020

Genetic variation not linked with differences in COVID-19 morbidity and mortality

A comprehensive search of genetic variation databases has revealed no significant differences across populations and ethnic groups in seven genes associated with viral entry of SARS-CoV-2.

24 Sep 2020

Researchers solve the mystery of how giant molecular proton pump works

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a proton gradient that powers the generation of ATP, the cell's fuel.

24 Sep 2020

Prevalence of SARS-CoV-2 with D614G mutation in a second wave infection in Houston

A recent study reveals that the genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detected in the initial phase of coronavirus disease 2019 (COVID-19) pandemic differ from the variants detected in a massive second wave of infection in Houston, Texas. The study is currently available on the medRxiv preprint server.

24 Sep 2020

Researchers uncover a new parvovirus strategy for reaching the cell nucleus

Researchers at the Institut national de la recherche scientifique (INRS), in collaboration with American scientists, have uncovered a new parvovirus strategy for reaching the cell nucleus which is their site of replication.

24 Sep 2020

Molecular analysis of COVID-19's second wave shows mutant viruses linked to rapid spread

Molecular analysis of COVID-19's powerful second wave in Houston – from May 12 to July 7 – shows a mutated virus strain linked to higher transmission and infection rates than the coronavirus strains that caused Houston's first wave.

24 Sep 2020

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

As scientists race to discover new and effective antiviral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many novel approaches are being utilized. Now, a new study published on the preprint bioRxiv in September 2020 reports on the discovery of a potentially beneficial enzyme blocker that could inhibit SARS-CoV-2 viral replication.

24 Sep 2020

Molecular insights may foster effective therapies for COVID-19 patients

Viral and bacterial pathogens wield pathogenic or virulent proteins that interact with high-value targets inside human cells, attacking what is known as the host interactome. The host interactome is the network map of all the protein-protein interactions inside cells.

24 Sep 2020

Researchers investigate molecular mechanism responsible for hypnotic effects of thalidomide

Thalidomide is a medication with several different effects, one of which is promoting sleep in the context of insomnia.

24 Sep 2020

Study reveals how loss of protein arginine methyltransferase affects proper brain development

Normal brain development requires a precise interplay between neuronal and non-neuronal (also called glial) cells.

24 Sep 2020

Researchers uncover an active role of glycans in SARS-CoV-2 spike protein

As the COVID-19 pandemic rages on, researchers are working overtime to develop vaccines and therapies to thwart SARS-CoV-2, the virus responsible for the disease Many efforts focus on the coronavirus spike protein, which binds the angiotensin-converting enzyme 2 (ACE2) on human cells to allow viral entry.

24 Sep 2020

NeutrobodyPlex nanobodies help monitor SARS-CoV-2 immune responses

Researchers recently described a set of 11 Nbs derived from an immunized alpaca which showed high-affinity binding to the glycosylated SARS-CoV-2 spike receptor domain (RBD) in a study published in the preprint server bioRxiv.

23 Sep 2020

New tool helps to find out toxins lurking in drinking water

Exposure to hydraulic fracturing fluid in drinking water has been shown to increase the risk of respiratory problems, premature births, congenital heart defects, and other medical problems. But not all wells are created equal.

23 Sep 2020

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

A fourth Phase 3 clinical trial evaluating an investigational vaccine for coronavirus disease 2019 (COVID-19) has begun enrolling adult volunteers.

23 Sep 2020

Researchers develop 'Trojan horse' approach to destroy cancer cells

Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found.

23 Sep 2020

Protein C News and Research

New experiments reveal how viruses initiate translation of genetic material into proteins

Human-to-cat transmission of SARS-CoV-2 confirmed

UNH awarded $1.8 million NIH grant to advance molecular research in diabetes and cancer

Two studies shed light on the biology and potential vulnerabilities of schistosomes

Linoleic acid binds SARS-CoV-2 spike protein

Research sheds light on how membrane proteins could be influenced by lipid environments

Genetic variation not linked with differences in COVID-19 morbidity and mortality

Researchers solve the mystery of how giant molecular proton pump works

Prevalence of SARS-CoV-2 with D614G mutation in a second wave infection in Houston

Researchers uncover a new parvovirus strategy for reaching the cell nucleus

Molecular analysis of COVID-19's second wave shows mutant viruses linked to rapid spread

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

Molecular insights may foster effective therapies for COVID-19 patients

Researchers investigate molecular mechanism responsible for hypnotic effects of thalidomide

Study reveals how loss of protein arginine methyltransferase affects proper brain development

Researchers uncover an active role of glycans in SARS-CoV-2 spike protein

NeutrobodyPlex nanobodies help monitor SARS-CoV-2 immune responses

New tool helps to find out toxins lurking in drinking water

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

Researchers develop 'Trojan horse' approach to destroy cancer cells

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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