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Variation in microRNAs may explain survival differences in breast cancer

Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with African American and Caucasian patients.

4 Jun 2012

Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting

Seattle Genetics, Inc. today announced that data from several clinical trials of ADCETRIS (brentuximab vedotin) will be presented at the 2012 American Society of Clinical Oncology (ASCO) Annual Meeting being held June 1-5, 2012 in Chicago, IL.

4 Jun 2012

Cancer patients with annual incomes below $50,000 less likely to participate in clinical trials

Cancer patients with annual household incomes below $50,000 were less likely to participate in clinical trials than patients with annual incomes of $50,000 or higher, and were more likely to be concerned about how to pay for clinical trial participation.

4 Jun 2012

Results from Janssen's ZYTIGA plus prednisone Phase 3 study on mCRPC

Results observed from pre-specified interim analyses of the randomized, placebo-controlled Phase 3 study, COU-AA-302, demonstrated that patients with metastatic castration-resistant prostate cancer (mCRPC) treated with abiraterone acetate (ZYTIGA) plus prednisone showed a statistically significant improvement in radiographic progression-free survival (rPFS) and all secondary endpoints compared to patients treated with placebo plus prednisone.

4 Jun 2012

Scientists propose new theory of the brain activity behind arm movements

Unlike their visual cousins, the neurons that control movement are not a predictable bunch. Scientists working to decode how such neurons convey information to muscles have been stymied when trying to establish a one-to-one relationship between a neuron's behavior and external factors such as muscle activity or movement velocity.

4 Jun 2012

New research: Foggers ineffective against bed bugs

Consumer products known as "bug bombs" or "foggers" have been sold for decades for use against many common household insects. However, recent research published in the Journal of Economic Entomology (JEE) shows these products to be ineffective against bed bugs.

4 Jun 2012

Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC

ArQule, Inc. and Daiichi Sankyo Co., Ltd. today announced final results from a randomized, placebo-controlled, double-blind, phase 2 clinical trial with the selective MET inhibitor tivantinib as a single-agent, investigational, second-line treatment in hepatocellular carcinoma (HCC).

4 Jun 2012

Affibody, GE Healthcare partner to develop Her2-targeted PET imaging agent

GE Healthcare signed an agreement with Affibody AB to collaborate on the development of a Her2-targeted PET imaging agent, which is scheduled to begin clinical trials later this year.

4 Jun 2012

Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC

Bristol-Myers Squibb Company today announced interim results from the expanded Phase 1 dose-ranging study 003 (n=296) of its investigational anti-PD-1 immunotherapy (BMS-936558), which showed clinical activity in patients with previously-treated non small-cell lung cancer (NSCLC), metastatic melanoma and renal cell carcinoma (RCC).

4 Jun 2012

Study reveals why GBM is highly resistant to current chemotherapies

New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies.

2 Jun 2012

New evidence of important role of next-generation sequencing in cancer treatment

Foundation Medicine, Inc., a molecular information company that brings comprehensive cancer genomic analysis to routine clinical care, today announced results from two studies using next-generation sequencing (NGS) to provide actionable information about genomic tumor alterations in individual patients' cancers across all solid tumor types.

2 Jun 2012

Algal DHA supplementation benefits during pregnancy and infancy

Positive results from clinical trials exploring algal DHA supplementation during pregnancy and infancy were presented this week at the 10th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL) – an international scientific society focused on research of dietary fats, oils and lipids.

2 Jun 2012

WHO to continue discussion on R&D reform focusing on health needs in developing countries

"Proposals for new mechanisms to improve the funding and coordination of health research for the developing world, potentially including a binding international convention, will be formally discussed over the next year, the World Health Assembly concluded last week (21–26 May) in Geneva, Switzerland," SciDev.Net reports.

2 Jun 2012

Innovative strategy for regenerating skeletal muscle tissue

An innovative strategy for regenerating skeletal muscle tissue using cells derived from the amniotic fluid is outlined in new research published by scientists at the UCL Institute of Child Health.

2 Jun 2012

Researchers uncover fundamental properties of key molecular signaling system using optical tweezers

By using a laser microbeam technology called optical tweezers, UC Irvine and UCLA researchers have uncovered fundamental properties of a key molecular signaling system involved with development, cancer and cardiovascular disease.

2 Jun 2012

Study finds natural ruminant trans fats not harmful

Canadian scientists are joining with international colleagues to lead new insights into the health implications of different types of trans fat.

2 Jun 2012

International community must sustain progress in reducing infant mortality rates

In this post in the Huffington Post's "World" blog, Cecilia Attias, former first lady of France and president and founder of the Cecilia Attias Foundation for Women, responds to a recent paper, published by the World Bank, which discusses significant declines in infant and under-five mortality in Kenya and across sub-Saharan Africa.

2 Jun 2012

New molecular test panel to enhance reliability of thyroid biopsy testing

Quest Diagnostics, the world's leading provider of diagnostic testing, information and services, today announced a new molecular test panel designed to help physicians determine if a thyroid gland is cancerous and requires surgical removal.

From Quest Diagnostics 2 Jun 2012

NIH awards $1.9M grant to study genetic control of cell migration

Developmental biologists Dominique Alfandari and Hélène Cousin at the University of Massachusetts Amherst recently received a five-year, $1.9 million grant from the U.S. National Institutes of Health to investigate craniofacial development in a frog model to better understand genetic control of cell migration.

2 Jun 2012

Engineered proteins demonstrate flu-fighting potency

Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral agents against a variety of flu virus strains, including H1N1 pandemic influenza.

2 Jun 2012

Research News and Research

Variation in microRNAs may explain survival differences in breast cancer

Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting

Cancer patients with annual incomes below $50,000 less likely to participate in clinical trials

Results from Janssen's ZYTIGA plus prednisone Phase 3 study on mCRPC

Scientists propose new theory of the brain activity behind arm movements

New research: Foggers ineffective against bed bugs

Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC

Affibody, GE Healthcare partner to develop Her2-targeted PET imaging agent

Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC

Study reveals why GBM is highly resistant to current chemotherapies

New evidence of important role of next-generation sequencing in cancer treatment

Algal DHA supplementation benefits during pregnancy and infancy

WHO to continue discussion on R&D reform focusing on health needs in developing countries

Innovative strategy for regenerating skeletal muscle tissue

Researchers uncover fundamental properties of key molecular signaling system using optical tweezers

Study finds natural ruminant trans fats not harmful

International community must sustain progress in reducing infant mortality rates

New molecular test panel to enhance reliability of thyroid biopsy testing

NIH awards $1.9M grant to study genetic control of cell migration

Engineered proteins demonstrate flu-fighting potency

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