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LDK378 compound well-tolerated in patients with ALK+ NSCLC

A new compound that targets anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer is well-tolerated by patients and is already showing early signs of activity, including in patients who no longer respond to crizotinib-the only approved ALK inhibitor. Results of this Novartis-sponsored sudy will be presented by a researcher from Fox Chase Cancer Center during the 2012 Annual Meeting of the American Society of Clinical Oncology on Sunday, June 3.

2 Jun 2012

Pakistan looks to India for guidance on polio eradication efforts

"Impressed with India's successful effort in polio eradication," a nine-member Pakistani delegation on Thursday met India's health minister Ghulam Nabi Azad and senior officials of the Ministry to discuss the country's polio eradication program, the Press Trust of India/Business Standard reports, noting that India achieved a polio-free status as of January.

2 Jun 2012

New medication proves effective in slowing the spread of metastatic prostate cancer

A new medication proved effective in slowing the spread of metastatic prostate cancer, while helping to maintain the quality of life, in patients with advanced disease. The phase 3 study was unblinded midway, allowing patients receiving the placebo to instead take the drug because of the favorable results.

2 Jun 2012

Global cancer rates could go up 75% by 2030, study suggests

"The number of people with cancer is set to surge by more than 75 percent across the world by 2030, with particularly sharp rises in poor countries as they adopt unhealthy 'Westernized' lifestyles," according to a study published Friday in the Lancet, Reuters reports.

2 Jun 2012

HIV markets in rich, poor countries are two distinct markets

HIV drugs have not only "transformed a fatal disease into a chronic one," but "[t]hey have also made HIV a big business," this Economist editorial states.

2 Jun 2012

States taking sides on NYC sugary soda restrictions

A plan by New York City Mayor Michael Bloomberg to limit the sale of large sugary drinks is being met by apprehension by the food industry as other states' leaders consider what example the restrictions could provide for them.

2 Jun 2012

Strong causal link between alcohol consumption and serious palpitations in patients with AF

The term "holiday heart syndrome" was coined in a 1978 study to describe patients with atrial fibrillation who experienced a common and potentially dangerous form of heart palpitation after excessive drinking, which can be common during the winter holiday season. The symptoms usually went away when the revelers stopped drinking. Now, research from UCSF builds on that finding, establishing a stronger causal link between alcohol consumption and serious palpitations in patients with atrial fibrillation, the most common form of arrhythmia.

2 Jun 2012

Effective strategies urgently needed to stop the progression of childhood obesity

National data show that currently more than 10 percent of preschoolers in the United States are obese, and an additional 10 percent are overweight. In a recently published article, a researcher from the Perelman School of Medicine at the University of Pennsylvania, in collaboration with peers and colleagues from across the nation, says that effective strategies to target pregnancy, infancy, and toddlers are urgently needed to stop the progression of childhood obesity.

2 Jun 2012

Study identifies new genetic factor associated with lean diabetes

Type 2 diabetes is popularly associated with obesity and a sedentary lifestyle. However, just as there are obese people without type 2 diabetes, there are lean people with the disease.

2 Jun 2012

Precision Therapeutics’ ChemoFx test feasible in cervical cancer

Precision Therapeutics announces the acceptance of a new abstract on the ChemoFx® in vitro drug response marker for publication in conjunction with the American Society of Clinical Oncology (ASCO) 2012 Annual Meeting.

2 Jun 2012

Imaging of blood flow provides new way to look into cardiac abnormalities and dysfunction

Researchers from Mount Sinai School of Medicine are pioneering new ultrasound techniques that provide the first characterization of multidirectional blood flow in the heart. By focusing on fluid dynamics - specifically, the efficiency with which blood enters and exits the heart's left ventricle - the researchers believe they can detect heart disease even when traditional measures show no sign of trouble.

2 Jun 2012

HNC patients may be at increased risk for post-treatment side effects

New data from an Internet-based study show that patients with head and neck cancers (HNC) may be at risk for significant late effects after their treatment, but they're unlikely to discuss these and other survivorship care issues with their doctors.

2 Jun 2012

America's biopharmaceutical researchers work on many new approaches to fight cancer

America's biopharmaceutical research companies are testing 981 medicines and vaccines to fight the many types of cancer affecting millions of patients worldwide, according to a report released today by the Pharmaceutical Research and Manufacturers of America.

2 Jun 2012

Study identifies several proteins as new therapeutic targets and biomarkers for kidney cancer

Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up validation testing, inhibition of these proteins and several related pathways holds promise as a form of therapy to slow the growth of kidney tumors.

2 Jun 2012

Academy of Nutrition and Dietetics encourages people to make healthy food choices

New York City has announced plans to ban the sale of sodas and other sugary beverages larger than 16 ounces in restaurants and entertainment venues. The Academy of Nutrition and Dietetics encourages consumers to be aware of how all beverages fit into their healthful daily eating plan.

2 Jun 2012

Inhibiting IRE1α-XBP1 pathway impacts survival of myeloma cells

Results published in Blood, the official journal of the American Society of Hematology, confirm that inhibition of the IRE1α-XBP1 pathway impacts the survival of myeloma cells, suggesting a promising therapeutic option in multiple myeloma.

2 Jun 2012

First U.S.-based study to assess per-patient annual economic costs of fecal incontinence

Care for patients with fecal incontinence costs $4,110 per person for both medical and non-medical costs like loss of productivity, according to new research from the University of Michigan.

2 Jun 2012

Montefiore experts available to discuss cancer research at 2012 ASCO meeting

Bringing together international experts with the latest technologies and pioneering research, Montefiore Einstein Center for Cancer Care, in collaboration with the National Cancer Institute-designated Albert Einstein Cancer Center, advances the front lines of prevention, diagnosis and treatment of rare and common cancers.

2 Jun 2012

European Multidisciplinary Meeting on Urological Cancers to be held in Barcelona

With the goal to deliver an in-depth review of the latest multi-modal management strategies for urological cancers, the 4th European Multidisciplinary Meeting on Urological Cancers (EMUC) will be held from 16 to 18 November 2012 in Barcelona, Spain.

2 Jun 2012

Lilly, Kowa announce results from PREVAIL U.S. study

Kowa Pharmaceuticals America, Inc. and Eli Lilly and Company today announced results of the PREVAIL U.S. study (Pitavastatin compaREd with praVAstatin In Lowering LDL-C in the U.S.) which evaluated the efficacy of LIVALO (pitavastatin) 4 mg compared with pravastatin 40 mg in reducing low-density lipoprotein cholesterol (LDL-C), the primary endpoint, as well as effects on other lipid parameters and lipoprotein particles in adult patients with primary hyperlipidemia or mixed dyslipidemia.

2 Jun 2012

Research News and Research

LDK378 compound well-tolerated in patients with ALK+ NSCLC

Pakistan looks to India for guidance on polio eradication efforts

New medication proves effective in slowing the spread of metastatic prostate cancer

Global cancer rates could go up 75% by 2030, study suggests

HIV markets in rich, poor countries are two distinct markets

States taking sides on NYC sugary soda restrictions

Strong causal link between alcohol consumption and serious palpitations in patients with AF

Effective strategies urgently needed to stop the progression of childhood obesity

Study identifies new genetic factor associated with lean diabetes

Precision Therapeutics’ ChemoFx test feasible in cervical cancer

Imaging of blood flow provides new way to look into cardiac abnormalities and dysfunction

HNC patients may be at increased risk for post-treatment side effects

America's biopharmaceutical researchers work on many new approaches to fight cancer

Study identifies several proteins as new therapeutic targets and biomarkers for kidney cancer

Academy of Nutrition and Dietetics encourages people to make healthy food choices

Inhibiting IRE1α-XBP1 pathway impacts survival of myeloma cells

First U.S.-based study to assess per-patient annual economic costs of fecal incontinence

Montefiore experts available to discuss cancer research at 2012 ASCO meeting

European Multidisciplinary Meeting on Urological Cancers to be held in Barcelona

Lilly, Kowa announce results from PREVAIL U.S. study

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