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Hormone therapy decreases metabolites directly linked with Type 2 diabetes

The Women's Health Initiative remains one of the most highly quoted when debating the benefits and risks of hormone therapy.

24 Sep 2019

Gum disease associated with greater risk of high blood pressure

People with gum disease (periodontitis) have a greater likelihood of high blood pressure (hypertension), according to a study published today in Cardiovascular Research, a journal of the European Society of Cardiology.

24 Sep 2019

Research: Protein complex represents a new metabolic target for liver cancer

Disrupting a metabolic pathway in the liver in a way that creates a more "cancer-like" metabolism actually reduces tumor formation in a mouse model of liver cancer.

24 Sep 2019

Dogs can suffer from same autoimmune encephalitis as humans, research reveals

Researchers from North Carolina State University have found that dogs can suffer from the same type of autoimmune encephalitis that people do. The finding could lead to better screening methods for diagnosis and possibly more effective treatments for canine encephalitis.

24 Sep 2019

Scientists to present new findings on gene therapy at Neuroscience 2019

Gene therapy shows promise as a way to treat and cure presently incurable neurological diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).

24 Sep 2019

Wake Forest Baptist receives multimillion-dollar grant for innovative cancer care research

For the second time in five years, Wake Forest Baptist Health has been recognized for its expertise in conducting innovative cancer care research by the National Cancer Institute's Community Oncology Research Program with a multimillion-dollar grant.

23 Sep 2019

Light-activated metal compound cuts off cancer cell's 'power source'

A space-age metal that formed part of the asteroid that destroyed the dinosaurs could provide a new method of treating cancer tumors selectively using light.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

UCSF launches new initiative to accelerate prostate cancer research

UC San Francisco announced Thursday it will establish the UCSF Benioff Initiative for Prostate Cancer Research, made possible by a $35 million gift from Marc and Lynne Benioff.

23 Sep 2019

Faster, cheaper, better: improved gene therapy tool production

The heart of modern therapy is increasingly personalized and targeted at specific cellular or genetic deficits. This requires gene therapy, in many cases. A new study, published on 19 September 2019 in the journal Nature, describes an improved way to produce purified gene carrier viruses called AAVs cheaply and quickly, from the culture medium.

22 Sep 2019

New study identifies potential enzyme target for diabetic retinopathy

A new study shows that diabetic retinopathy (DR), or retinal disease caused by the high blood glucose levels in diabetes mellitus, is due to the death of retinal cells because of the high levels of a pro-enzyme called lysyl oxidase propeptide (LOX-PP). This could help researchers develop specific treatments by targeting this molecule.

22 Sep 2019

RNA hitches lysosome rides to make proteins far away from the nucleus

Proteins inside a cell are often made at the site where they are used, rather than being shipped long distances. This is so with nerve cells which have long cell extensions in the form of axons and dendrites, up to four feet long in some case

22 Sep 2019

Identification and management of depression in people with epilepsy to save lives

Depression is the most common psychiatric comorbidity in people with epilepsy. Clinical studies have found that 20% to 30% of people with epilepsy have depression; the incidence may be as high as 50% to 55% in people visiting hospital epilepsy centers.

21 Sep 2019

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.

21 Sep 2019

Advancements in pain management are giving new options to patients

Hardly a day goes by without the public being warned about the dangers of opioids. But still, according to the National Institute on Drug Abuse, more than 130 people die every day of opioid overdose and the problem is getting worse.

21 Sep 2019

New clinical trial tests immunotherapy drug for prostate cancer patients on active surveillance

Stephenson Cancer Center Testing Drug for Prostate Cancer Patients on Active Surveillance OKLAHOMA CITY - Men who are diagnosed with low-risk prostate cancer usually opt for active surveillance - a monitoring of their cancer over time without undergoing treatments that would cause side effects.

20 Sep 2019

Pembrolizumab provides added benefit for subpopulations of patients with metastatic NSCLC

In early July, the German Institute for Quality and Efficiency in Health Care conducted two early benefit assessments to investigate whether certain drug combinations with pembrolizumab have advantages in comparison with the respective appropriate comparator therapy for patients with metastatic squamous or non-squamous non-small cell lung cancer.

20 Sep 2019

Novel gene therapy for glycogen storage disease shows positive results

At the Association for Glycogen Storage Disease's 41st Annual Conference, Dr. David Weinstein of UConn School of Medicine and Connecticut Children's presented his groundbreaking, one-year clinical trial results for the novel gene therapy treatment for glycogen storage disease.

20 Sep 2019