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Study shows how streamlined patient pathways may improve efficiency of healthcare delivery

The Alliance for Home Health Quality and Innovation (the Alliance) today released research detailing the care pathways patients receive for three distinct episode types: post-acute, pre-acute and non-post-acute.

23 May 2012

Severe hypersensitivity reactions to anti-HIV drug occur through autoimmune mechanism

Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according to a study published online by the journal AIDS, official journal of the International AIDS Society.

23 May 2012

Few new chemicals are in development for malaria vector control

"This issue has been building for some time. It is really no surprise as insects have become resistant to nearly all insecticides given time and selection pressure. Few new chemicals are in development for malaria vector control, because there is little profit to be made by the poorest of the world's poor — who feel the brunt of the malaria burden.

23 May 2012

Study shows how chromosomal mutation likely contributes to early development of prostate cancer

Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill Cornell Medical College researchers have found that in these cancer cells, the 3-D architecture of DNA, wrapped up in a little ball known as a chromatin, is warped in such a way that a switch has been thrown on thousands of genes, turning them on or off to promote abnormal, unchecked growth. Researchers also found that new chromosomal translocations form, further destabilizing the genome.

23 May 2012

Researchers to initiate Crenezumab clinical trial to treat Alzheimer's

After an announcement by federal officials approving clinical trials for the drug Crenezumab, researchers searching for a way to treat Alzheimer's Disease are gearing up for a rare study that will allow them to test a therapy for a genetically predestined disease -- before its onset.

23 May 2012

Researchers generate neuronal cells from patients with Fragile X syndrome

Researchers at the Hebrew University of Jerusalem have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. The discovery paves the way for research that will examine restoration of normal gene expression in Fragile X patients.

23 May 2012

First Edition: May 23, 2012

Today's headlines include reports about the CBO's dire predictions about a possible recession as well as details about how health policy is handled in new presidential campaign ads.

23 May 2012

Panel of HuCAL Anti-Drug Antibodies to be launched by AbD Serotec

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) announced today that its division for research and diagnostic antibodies, AbD Serotec, will launch a series of novel anti-drug antibodies (ADAs) to strengthen its position as a leading provider of diagnostic reagents.

23 May 2012

Invest in proven ways to curb maternal mortality, morbidity

Christy Turlington Burns, maternal health advocate and founder of Every Mother Counts, notes in this GlobalPost "Global Pulse" opinion piece that "99 percent of women who die during or after childbirth live in the developing world," and women and girls ages 19 and younger are at a higher risk of maternal mortality and morbidity.

23 May 2012

New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer

Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. As an integral part of this system, heat shock protein 90 (HSP90) has been shown to help malignant cells accommodate the genetic changes and profound disturbances in normal biology that occur in cancers.

23 May 2012

VCU Center on Health Disparities to research into preterm birth

The Virginia Commonwealth University Center on Health Disparities has been awarded a five-year grant renewal totaling $6.2 million from the National Institute of Health's Institute on Minority Health Disparities for research, research training and community outreach in the area of preterm birth.

23 May 2012

Nighttime intensivists can improve ICU patient outcomes

Intensive care units (ICUs) that have no or limited access to critical care doctors during the day can improve patient outcomes by having the specialists, called intensivists, staff the unit at night, according to a study led by researchers at the University of Pittsburgh School of Medicine and UPMC.

23 May 2012

Proper care of diabetic foot infections can save limbs, lives

Diabetic foot infections are an increasingly common problem, but proper care can save limbs and, ultimately, lives, suggest new guidelines released by the Infectious Diseases Society of America.

23 May 2012

Scientists identify key mechanism in development of Alzheimer's

New research by scientists at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine (UMDNJ-SOM) demonstrates how dying or damaged brain cells release debris into the bloodstream and give rise to specific autoantibodies that appear to be reliable biomarkers for early diagnosis of Alzheimer's and other neurodegenerative diseases.

23 May 2012

Federal task force recommends dropping routine prostate cancer test

The U.S. Preventive Services Task Force finds scant evidence that the PSA blood test saves lives and instead says unneeded treatment leads to serious problems, including impotence and incontinence.

23 May 2012

New BAP guidelines target treatment of substance abuse, addiction

The British Association for Psychopharmacology (BAP) has released fresh guidelines on the best methods to treat substance abuse and addiction in the Journal of Psychopharmacology, published by SAGE.

23 May 2012

U.S. to provide $30M in assistance through USAID to World Food Programme for South Sudan

The U.S. Government, through USAID, is providing $30 million in emergency assistance to people affected by conflict and food insecurity in South Sudan, United Press International reports.

23 May 2012

Tavenner confirmation hearing not in the Senate's plans

The Wall Street Journal reports that, after months of speculation, Senate Democrats have indicated they aren't planning a confirmation hearing for Centers for Medicare & Medicaid Services acting administrator Marilyn Tavenner.

23 May 2012

Billion-dollar Davita deal highlights movement toward mergers, accountable care organizations

This particular deal, in which DaVita will acquire HealthCare Partners, will enable the dialysis services provider to offer a more integrated group of services that fall under the ACO model that the government is trying to encourage.

23 May 2012

Mimotopes can help develop new diagnostic tests for sleeping sickness

Each year many thousands of Africans contract sleeping sickness. The cause is a unicellular parasite, a trypanosome, which is transmitted by the bite of tsetse flies. First the parasite multiplies in blood and lymph, while evading the human immune system. It then lodges in organs like heart and kidneys and finally in the brain. Patients become disoriented, their sleeping pattern disintegrates and they get motor and mental problems.

23 May 2012

Research News and Research

Study shows how streamlined patient pathways may improve efficiency of healthcare delivery

Severe hypersensitivity reactions to anti-HIV drug occur through autoimmune mechanism

Few new chemicals are in development for malaria vector control

Study shows how chromosomal mutation likely contributes to early development of prostate cancer

Researchers to initiate Crenezumab clinical trial to treat Alzheimer's

Researchers generate neuronal cells from patients with Fragile X syndrome

First Edition: May 23, 2012

Panel of HuCAL Anti-Drug Antibodies to be launched by AbD Serotec

Invest in proven ways to curb maternal mortality, morbidity

New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer

VCU Center on Health Disparities to research into preterm birth

Nighttime intensivists can improve ICU patient outcomes

Proper care of diabetic foot infections can save limbs, lives

Scientists identify key mechanism in development of Alzheimer's

Federal task force recommends dropping routine prostate cancer test

New BAP guidelines target treatment of substance abuse, addiction

U.S. to provide $30M in assistance through USAID to World Food Programme for South Sudan

Tavenner confirmation hearing not in the Senate's plans

Billion-dollar Davita deal highlights movement toward mergers, accountable care organizations

Mimotopes can help develop new diagnostic tests for sleeping sickness

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