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Airway inflammation linked with asthma-related mortality rates in older adults

Higher mortality rates among older adult asthma patients compared to their younger counterparts may be due, at least in part, to an increase in airway inflammation, according to a study conducted by researchers in Canada, who note that their results imply that elderly patients are either less likely to follow asthma medication dosing instructions, or that the underlying airway inflammation in elderly patients is relatively resistant to current anti-inflammatory therapies.

22 May 2012

Heart disease risk assessment tools often underestimate CVD danger faced by RA patients

Heart disease risk assessment tools commonly used by physicians often underestimate the cardiovascular disease danger faced by rheumatoid arthritis patients, a Mayo Clinic study has found. Inflammation plays a key role in putting those with rheumatoid arthritis in greater jeopardy for heart disease, yet many cardiovascular disease risk assessment methods do not factor it in, the researchers note.

22 May 2012

Polarization Gating Spectroscopy may detect pancreatic cancer

By simply shining a tiny light within the small intestine, close to that organ's junction with the pancreas, physicians at Mayo Clinic's campus in Florida have been able to detect pancreatic cancer 100 percent of the time in a small study.

22 May 2012

Data from EarlySense contact-free monitor clinical study presented at ATS conference

EarlySense, a market leader in proactive patient care solutions, announced today the results of a clinical study conducted at a Dignity Health Hospital. The data was presented today in a poster presentation titled: Effect Of Contactless Continuous Patient Monitoring In A Medical-Surgical Unit On Intensive Care Unit Transfers: A Controlled Clinical Trial at the ATS International Conference in San Francisco.

22 May 2012

Noninvasive test can reduce feeding-related complications among premature infants

Tufts Medical Center researchers have shown that presence of a gene strongly linked to appetite regulation is highly predictive of a premature infant's readiness to feed orally. An analysis of just a drop of an infant's saliva could be the key to preventing many feeding problems and the expensive medical complications that can occur when infants are fed by mouth too early.

22 May 2012

European study on allergies investigates birch, olive and grass pollens

From Finland to Italy and from Spain to Lithuania, thirteen research institutes from eleven European countries took part in the three-year Hialine study. The coordinator was Professor Dr Jeroen Buters of TUM's Chair of Molecular Allergology and the Center of Allergy & Environment.

22 May 2012

FSU announces availability of Pacifier Activated Lullaby device

Many premature babies enter the world with a mountain of challenges in front of them. Even after they overcome any life-threatening issues, they face ongoing, and typically unpleasant, medical procedures, long hospital stays and increased chances of chronic health issues throughout their lives.

22 May 2012

Investigators describe how they synthesized polymers to stabilize proteins

Proteins are widely used as drugs - insulin for diabetics is the best known example - and as reagents in research laboratories, but they react poorly to fluctuations in temperature and are known to degrade in storage.

22 May 2012

TransCytos, Enginasion collaborate to develop new transfection technology

Enginasion and TransCytos announced today that their collaboration has resulted in a prototype 'transfection' technology that is designed to have a dramatic and positive impact on the drug-research industry.

22 May 2012

UAB creates Program in Environmental and Translational Medicine

The University of Alabama at Birmingham has created a Program in Environmental and Translational Medicine, a multi-faceted approach to dealing with health issues tied to environmental origins.

22 May 2012

New knowledge related to host-parasite interaction in severe malaria

Researchers from Seattle Biomedical Research Institute, the University of Copenhagen and the University of Edinburgh have uncovered new knowledge related to host-parasite interaction in severe malaria, concerning how malaria parasites are able to bind to cells in the brain and cause cerebral malaria - the most lethal form of the disease.

22 May 2012

Intermountain signs collaborative research agreement with Myriad

Intermountain Healthcare and Myriad Genetics today announced they have signed a collaborative research agreement. The purpose of this agreement is to perform research and validation studies on transformative molecular diagnostic tests being developed by Myriad in an effort to improve the care and treatments for patients at Intermountain and around the world.

22 May 2012

Combination of vitamin D and BCG vaccine improves bladder cancer survival

The tuberculosis vaccine is often used as a treatment for bladder cancer, and adding vitamin D might improve the vaccine's effectiveness, according to new research from the University of Rochester Medical Center presented today at the American Urological Association annual meeting.

22 May 2012

Liposuction surgery reduces risk of ultraviolet-light induced skin cancer

Is it possible that liposuction or other fat removal procedures are beneficial for treating obesity and reducing the risk of cancer? When it comes to humans, scientists can't answer that question. They know that obesity increases the risk of heart disease, diabetes and cancer. But there have not been clinical studies to determine if the surgical removal of fat tissue would decrease cancer risk in humans.

22 May 2012

HSF-1 protein likely source of chemotherapy-related heart damage in mice

Blocking a protein in the heart that is produced under stressful conditions could be a strategy to prevent cardiac damage that results from chemotherapy, a new study suggests.

22 May 2012

New strategy can reactivate genes that cause cancer tumors to shrink and die

A team of scientists has developed a promising new strategy for "reactivating" genes that cause cancer tumors to shrink and die. The researchers hope that their discovery will aid in the development of an innovative anti-cancer drug that effectively targets unhealthy, cancerous tissue without damaging healthy, non-cancerous tissue and vital organs.

22 May 2012

Behavior support intervention can help reduce blood pressure in African-Americans

Behavioral support from peers and primary care office staff can help patients improve their blood pressure control by as much as starting a new drug, a new study found. Barbara J. Turner, M.D., M.S.Ed., M.A., M.A.C.P., of UT Medicine San Antonio, is the senior author.

22 May 2012

First insight into links between microbes and developing infant

A new multi-university study reports that differences in bacterial colonization of the infant gut in formula-fed and breast-fed babies lead to changes in the expression of genes involved in the infant's immune system.

22 May 2012

Data from Janssen’s SIMPONI Phase 3 study on ulcerative colitis

New study findings presented today show that subcutaneous induction regimens of the anti-tumor necrosis factor (TNF)-alpha therapy SIMPONI (golimumab) induced clinical response in a majority of patients with moderately to severely active ulcerative colitis (UC) who had previously failed or were intolerant to conventional agents.

22 May 2012