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Mount Sinai cancer researchers to present several landmark studies at ASCO meeting

Mount Sinai School of Medicine researchers will present several landmark studies, including data on treatment trends in late-stage cancer, a promising multiple myeloma vaccine, and predictive models of soft tissue sarcomas, prostate and bladder cancer, at the 2012 American Society of Clinical Oncology (ASCO) meeting June 1-5, 2012 in Chicago.

19 May 2012

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have identified the mechanism by which protein Zds1 regulates a key function in mitosis, the process that occurs immediately before cell division.

19 May 2012

Childhood cancer research computing cluster to support precision medicine clinical trial

The childhood cancer research computing cluster created and donated by Dell for the Translational Genomics Research Institute (TGen) is ready to support the world's first precision medicine clinical trial for pediatric cancer.

19 May 2012

UK-led technologies set to transform treatments on the NHS

Video games, pioneering gene therapies and new medical devices are set to transform treatments on the NHS, with support from the Department of Health and the Wellcome Trust.

19 May 2012

PharMEDium to present enhanced labeling for ICU services at NTI and Critical Care Expo

Amy Langan, Vice President of Marketing and Business Development, announced that PharMEDium will highlight its enhanced labeling for sterile intravenous compounded ICU Services at the National Teaching Institute (NTI) and Critical Care Exposition, May 19-24, 2012 in Orlando, Florida.

19 May 2012

Rare DNA variations may be responsible for differences in susceptibility to common disorders

One-letter switches in the DNA code occur much more frequently in human genomes than anticipated, but are often only found in one or a few individuals. The abundance of rare variations across the human genome is consistent with the population explosion of the past few thousand years, medical geneticists and evolutionary biologists report in the May 17 advanced online edition of Science.

19 May 2012

Exercise could reduce risk of asthma symptoms or attacks

Not only is it safe for people with asthma to exercise, but doing so could reduce their risk of asthma symptoms or attacks, according to a new evidence review in The Cochrane Library.

19 May 2012

Screening lung cancer tumor samples for genetic mutations can help tailor personalized treatment

Screening lung cancer tumor samples for cancer-causing, or "driver," genetic mutations can help physicians tailor patients' treatments to target those specific mutations. While scientists have identified cancer-causing mutations for the majority of lung adenocarcinomas — the most common type of non-small cell lung cancer — and have developed drugs that can successfully address them, scientists have not yet identified targeted therapies for another type of non-small cell lung cancer known as squamous cell carcinoma.

19 May 2012

Study focuses on role of the brain and mind in chronic and complex pain disorders

Training the brain to reduce pain could be a promising approach for treating phantom limb pain and complex regional pain syndrome, according to an internationally known neuroscience researcher speaking today at the American Pain Society's Annual Scientific Meeting.

19 May 2012

The Millennium Village Project: a correction

Paul Pronyk, lead author of the Millennium Village paper, releases the following statement about the paper, Pronyk PM, Muniz M, Nemser B, et al, for the Millennium Villages Study Group. The effect of an integrated multisector model for achieving the Millennium Development Goals and improving child survival in rural sub-Saharan Africa: a non-randomised controlled assessment. Lancet 2012; published online May 8. DOI:10.1016/S0140-6736(12)60207-4.

18 May 2012

Promising updates in quest for early detection and treatments for lung cancer

LUNGevity Foundation, the nation's largest lung cancer-focused nonprofit, is pleased to note promising updates in researchers' quest for early detection and treatments for lung cancer during May, Lung Cancer Hope Month.

18 May 2012

Ventac and GIBH announce creation of CASiGEN Pharma

Ventac Partners and the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences (GIBH) today announced the creation of CASiGEN Pharma Ltd. (CASiGEN) to bring new treatments for diabetes and other metabolic disorders to the global market.

18 May 2012

PLoS blog responds to U.N.'s newly released maternal mortality estimates

Newly released "estimates of maternal mortality from the United Nations' Maternal Mortality Estimation Inter-Agency Group (MMEIG) are good news – but not good enough," Peter Byass, professor of global health at Umea University in Sweden and director of the Umea Centre for Global Health Research, writes in this post in the PLoS "Speaking of Medicine" blog.

18 May 2012

Scientists map how XIAP protein activates vital component of immune defence system

Defects in the gene that encodes the XIAP protein result in a serious immune malfunction. Scientists used biochemical analyses to map the protein's ability to activate vital components of the immune system. Their results have recently been published in Molecular Cell, a journal of international scientific repute.

18 May 2012

Despite bishop's disapproval, Sebelius will speak at Georgetown University

The Health and Human Services secretary was invited in January to address graduates of the Public Policy Institute at the Jesuit institution.

18 May 2012

Migraine is a neurological, not vascular, disorder

The latest genetic and biological research shows that migraine is a neurological, not vascular, disorder and both acute and preventive treatments being developed target peripheral and central nervous systems, according to a prominent migraine expert addressing the American Pain Society (APS)today.

18 May 2012

Budget politics and posturing continues at both ends of Pennsylvania Avenue

Even as congressional leaders met with President Barack Obama on budget matters, the Senate voted on -- and rejected -- a series of budget proposals. Meanwhile, House Speaker John Boehner draws a line in the sand regarding the next vote to raise the federal debt limit.

18 May 2012

ACO model may improve populations-based outcomes for pain management

How will pain care be influenced by the anticipated reforms in the U.S. healthcare system? Current models of healthcare delivery offer both obstacles and opportunities for achieving quality and effectiveness in pain-related care, according to Daniel Carr, MD, Tufts University in his keynote address at the American Pain Society Annual Scientific Meeting.

18 May 2012

One Blog interviews USAID deputy administrator about upcoming G8 Summit

ONE Blog interviews Ambassador Don Steinberg, current deputy administrator at USAID, about the upcoming G8 Summit.

18 May 2012

Urocortin 2 improves cardiac output in Phase II study for acute decompensated heart failure

Neurocrine Biosciences, Inc. today announced efficacy and safety results from a Phase II trial of urocortin 2 in 53 patients with acute decompensated heart failure. The UNICORN study was conducted over approximately a two year period by the Cardioendocrine Research Group from the University of Otago in Christchurch, New Zealand and included patients admitted to Christchurch Hospital with acute decompensated heart failure.

18 May 2012

Research News and Research

Mount Sinai cancer researchers to present several landmark studies at ASCO meeting

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Childhood cancer research computing cluster to support precision medicine clinical trial

UK-led technologies set to transform treatments on the NHS

PharMEDium to present enhanced labeling for ICU services at NTI and Critical Care Expo

Rare DNA variations may be responsible for differences in susceptibility to common disorders

Exercise could reduce risk of asthma symptoms or attacks

Screening lung cancer tumor samples for genetic mutations can help tailor personalized treatment

Study focuses on role of the brain and mind in chronic and complex pain disorders

The Millennium Village Project: a correction

Promising updates in quest for early detection and treatments for lung cancer

Ventac and GIBH announce creation of CASiGEN Pharma

PLoS blog responds to U.N.'s newly released maternal mortality estimates

Scientists map how XIAP protein activates vital component of immune defence system

Despite bishop's disapproval, Sebelius will speak at Georgetown University

Migraine is a neurological, not vascular, disorder

Budget politics and posturing continues at both ends of Pennsylvania Avenue

ACO model may improve populations-based outcomes for pain management

One Blog interviews USAID deputy administrator about upcoming G8 Summit

Urocortin 2 improves cardiac output in Phase II study for acute decompensated heart failure

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