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Omeros announces license agreement with Daiichi Sankyo for PDE7 inhibitors

Omeros Corporation today announced that its exclusive license to phosphodiesterase 7 inhibitors from Daiichi Sankyo Co., Ltd. has been amended to include addiction and compulsive disorders in the field of use.

23 Feb 2011

Cerasome filled molecular-sized bubbles to target liver cancer cells

Nanotechnology may open a new door on the treatment of liver cancer, according to a team of Penn State College of Medicine researchers. They used molecular-sized bubbles filled with chemotherapy drugs to prevent cell growth and initiate cell death in test tubes and mice.

23 Feb 2011

Tifacogin administration shows no treatment benefit in patients with severe CAP

Use of the blood clot-inhibiting medication tifacogin does not appear to improve outcomes of patients with severe community-acquired pneumonia, according to a study conducted by researchers from North and South America, Europe, Asia and Africa. The drug had shown some potential benefit in the sCAP subgroup of an earlier trial involving sepsis patients.

23 Feb 2011

Positive results from Harbor BioSciences' Triolex initial preclinical study for treatment of PD

Harbor BioSciences, Inc., which is investigating the use the company's proprietary compound Triolex as a treatment for Parkinson's disease with funding from The Michael J. Fox Foundation, announced positive results in initial preclinical studies.

23 Feb 2011

USPTO issues Notice of Allowance to Somaxon's Silenor patent application

Somaxon Pharmaceuticals, Inc., a specialty pharmaceutical company, today announced that it has received a Notice of Allowance from the United States Patent and Trademark Office for claims in U.S. patent application no. 11/781,165.

23 Feb 2011

Regeneron submits VEGF Trap-Eye BLA to FDA for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. announced that the company submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for VEGF Trap-Eye for the treatment of the neovascular form of age-related macular degeneration (wet AMD). Under the Prescription Drug User Fee Act (PDUFA), the goal for a standard review time from submission to FDA action is ten months.

22 Feb 2011

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced the initiation of the randomized Phase 2 portion of the trial of IPI-926 in combination with gemcitabine in patients with previously untreated, metastatic, pancreatic cancer.

22 Feb 2011

Nitroglycerin ointment may help in improving older women’s bone health: Study

A new study has shown that nitroglycerin ointment, that is used for chest pain or angina can be beneficial in postmenopausal women in improving their bone density. In this group of women, the bone becomes increasingly weak and brittle and leads to easy fractures. The study showed that postmenopausal women who used it for 2 years showed a modest increase in bone mineral density and decrease in bone resorption (loss). The study was published in the February 23 issue of JAMA.

22 Feb 2011

Pieris: New interim PRS-050 Phase I data against cancer to be presented at Tri-Conference in California

Pieris AG announced today the upcoming presentation of new preclinical and interim Phase I clinical trial data for its PRS-050 Anticalin(r) program, currently under evaluation for the treatment of cancer.

22 Feb 2011

MedTrust, Avantra collaborate to develop molecular diagnostic assay for cancer care

MedTrust Online and Avantra Biosciences announced today a novel collaboration to involve clinicians in the earliest stages of molecular diagnostic assay development for Avantra Biosciences' revolutionary QPDx multiplex immunoassay system.

22 Feb 2011

Educational intervention may increase awareness about kidney transplant recipients' risk of developing skin cancer

Sharing printed educational materials about the risk of squamous cell carcinoma with kidney transplant recipients appeared to be effective at increasing skin self-examination and encouraging follow-up with a dermatologist to determine risk of cancer, according to a report posted online today that will appear in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.

22 Feb 2011

Pharming, Santarus begin RHUCIN Phase IIIb study in patients with Hereditary Angioedema

Specialty biopharmaceutical company Santarus, Inc. and biotech company Pharming Group NV (NYSE Euronext: PHARM) today announced that Pharming has begun an international, multicenter, randomized, placebo-controlled Phase IIIb clinical study evaluating the investigational drug RHUCIN for the treatment of acute attacks of angioedema in patients with Hereditary Angioedema.

22 Feb 2011

Positive results from TMC435 phase 2b PILLAR study in treatment-naive patients with HCV

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, announces today further positive results from the phase 2b PILLAR study of TMC435 in treatment-naive patients with hepatitis C virus genotype-1.

22 Feb 2011

GE Healthcare, CDC collaborate to explore efficacy of actionable health alerts

After a full year of feasibility studies, the Centers for Disease Control and Prevention is taking a significant step toward providing public health information at the point-of-care. CDC is collaborating with GE Healthcare, a unit of General Electric Company, to explore the efficacy of actionable health alerts, delivered instantly to a physician's electronic medical record.

21 Feb 2011

Investigational heart valve implanted in patient through small puncture hole in leg

Physicians at the Methodist DeBakey Heart & Vascular Center in Houston implanted a new investigational heart valve in a patient through a small puncture hole in the leg.

21 Feb 2011

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

ADVANCELL, an emerging biopharmaceutical company, today announced positive results from a clinical study conducted with Acadra (Acadesine) in Chronic Lymphocytic Leukemia patients resistant to current therapies. The company also announced promising non-clinical results in Multiple Myeloma (MM), Mantle Cell Lymphoma (MCL) and other lymphoproliferative disorders. Synergism of Acadra in combination with current treatment in these indications has been demonstrated.

21 Feb 2011

Mouse model could help develop new classes of antidepressant drugs

The most widely prescribed antidepressants - medicines such as Prozac, Lexapro and Paxil - work by blocking the serotonin transporter, a brain protein that normally clears away the mood-regulating chemical serotonin. Or so the current thinking goes.

21 Feb 2011

Proper wound care may treat skin infections effectively than antibiotics in children with MRSA

When it comes to curing skin infected with the antibiotic-resistant bacterium MRSA, timely and proper wound cleaning and draining may be more important than the choice of antibiotic, according to a new Johns Hopkins Children's Center study. The work is published in the March issue of Pediatrics.

21 Feb 2011

New study: Venus White Pro whitens teeth up to 8.4 shades with virtually no sensitivity

Heraeus Kulzer, LLC, the leader in advancing dental esthetics and overall dental wellbeing, announced today the results of a new study that demonstrates that Venus White Pro whitens teeth up to 8.4 shades with virtually no sensitivity.

21 Feb 2011

QRxPharma granted FDA pre-NDA meeting, further phase II data released

QRxPharma Limited (ASX: QRX and OTCQX: QRXPY) announced today the granting of a pre-New Drug Application (NDA) meeting with the United States Food and Drug Administration (FDA) and successful completion of its third pivotal Phase 3 registration trial (study 009) for immediate-release MoxDuo.

20 Feb 2011

Efficacy News and Research

Omeros announces license agreement with Daiichi Sankyo for PDE7 inhibitors

Cerasome filled molecular-sized bubbles to target liver cancer cells

Tifacogin administration shows no treatment benefit in patients with severe CAP

Positive results from Harbor BioSciences' Triolex initial preclinical study for treatment of PD

USPTO issues Notice of Allowance to Somaxon's Silenor patent application

Regeneron submits VEGF Trap-Eye BLA to FDA for treatment of wet AMD

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

Nitroglycerin ointment may help in improving older women’s bone health: Study

Pieris: New interim PRS-050 Phase I data against cancer to be presented at Tri-Conference in California

MedTrust, Avantra collaborate to develop molecular diagnostic assay for cancer care

Educational intervention may increase awareness about kidney transplant recipients' risk of developing skin cancer

Pharming, Santarus begin RHUCIN Phase IIIb study in patients with Hereditary Angioedema

Positive results from TMC435 phase 2b PILLAR study in treatment-naive patients with HCV

GE Healthcare, CDC collaborate to explore efficacy of actionable health alerts

Investigational heart valve implanted in patient through small puncture hole in leg

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

Mouse model could help develop new classes of antidepressant drugs

Proper wound care may treat skin infections effectively than antibiotics in children with MRSA

New study: Venus White Pro whitens teeth up to 8.4 shades with virtually no sensitivity

QRxPharma granted FDA pre-NDA meeting, further phase II data released

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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