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Researchers identify genomic cellular map associated with hippocampal sclerosis

A multidisciplinary team led by researchers from the Spanish Research Council identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy.

8 Jun 2021

Researchers identify new approach to clear toxic Huntingtin protein

Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington's disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder.

2 Jun 2021

Distinct activity patterns in the prefrontal cortex reveal when white lie has selfish motives

You may think a little white lie about a bad haircut is strictly for your friend's benefit, but your brain activity says otherwise. Distinct activity patterns in the prefrontal cortex reveal when a white lie has selfish motives, according to new research published in JNeurosci.

2 Jun 2021

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found.

31 May 2021

Neuropathology of COVID-19 patients caused by infection of brain pericytes

Recently, researchers from the UK and Sweden used highly sensitive multiplexed immunohistochemistry to study the brain tissue of COVID-19 patients and controls to analyze ACE2 expression in brain pericytes of patients with neurological symptoms. They also used spatial immunophenotyping to assess inflammation in brain tissue of COVID-19 patients.

31 May 2021

REAER is a promising therapy for improving the lives of people with multiple sclerosis

A team of multiple sclerosis (MS) experts at Kessler Foundation led the first pilot randomized controlled trial of robotic-exoskeleton assisted exercise rehabilitation (REAER) effects on mobility, cognition, and brain connectivity in people with substantial MS-related disability.

29 May 2021

Blood oxygen levels may explain why memory loss is an early symptom of Alzheimer's disease

In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.

29 May 2021

White lies may not be so innocent after all – study reveals selfish motives behind white lies using functional MRI brain scans

A recent study published in The Journal of Neuroscience found that people who told a white lie had selfish motives for telling that lie.

28 May 2021

Researchers use anesthetics to study reemerging consciousness, cognitive function after anesthesia

Millions of surgical procedures performed each year would not be possible without the aid of general anesthesia, the miraculous medical ability to turn off consciousness in a reversible and controllable way.

27 May 2021

Italian HCW study reaffirms Pfizer-BioNTech effectiveness against COVID-19

Real-world data from Pasquale Stefanizzi of Aldo Moro University in Italy and colleagues confirm that the Pfizer-BioNTech vaccine effectively prevents COVID-19 infection.

26 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Altered blood flow in the brain may cause symptoms of Parkinson's disease

Patients who suffer from REM sleep behavior disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. In the long term, this may cause symptoms of Parkinson's disease. This is shown by research from Aarhus University and Aarhus University Hospital.

26 May 2021

Study highlights the importance of sensory connections in fear learning

Has your heart ever started to race at the thought of an upcoming deadline for work? Or has the sight of an unknown object in a dark room made you jump? Well, you can probably thank your amygdala for that.

25 May 2021

New insights into white matter changes may offer novel targets for prevention, therapies

ince 2008, researchers at Boston University School of Medicine (BUSM) and VA Boston Healthcare System have studied Chronic Traumatic Encephalopathy (CTE), a progressive brain disease associated with repetitive head impacts that has been diagnosed after death in the brains of American football players and other contact sport athletes as well as members of the armed services.

25 May 2021

Cortex News and Research

Researchers identify genomic cellular map associated with hippocampal sclerosis

Researchers identify new approach to clear toxic Huntingtin protein

Distinct activity patterns in the prefrontal cortex reveal when white lie has selfish motives

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

Neuropathology of COVID-19 patients caused by infection of brain pericytes

REAER is a promising therapy for improving the lives of people with multiple sclerosis

Blood oxygen levels may explain why memory loss is an early symptom of Alzheimer's disease

White lies may not be so innocent after all – study reveals selfish motives behind white lies using functional MRI brain scans

Researchers use anesthetics to study reemerging consciousness, cognitive function after anesthesia

Italian HCW study reaffirms Pfizer-BioNTech effectiveness against COVID-19

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Altered blood flow in the brain may cause symptoms of Parkinson's disease

Study highlights the importance of sensory connections in fear learning

New insights into white matter changes may offer novel targets for prevention, therapies

Researchers identify a supersensitized brain connection in people with misophonia

Study demonstrates the negative effects of HERV activation on human brain development

Study reveals three brain regions that link the brain's perception and memory systems

New, non-invasive method measures brain blood flow with light

Machine learning approach helps study human hypothalamus at the single-cell level

New implantable system can manipulate brain signals and suppress pathological coupling

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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