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New approach harnesses tumor's own machinery to produce immune-stimulating molecules

By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers have found a way to force tumors to trigger their own destruction.

3 Nov 2025

Smartphones match traditional methods in monitoring patients with muscular dystrophy

Stanford Medicine researchers found that a smartphone could monitor patients with two types of muscular dystrophy as well as traditional methods and diagnose conditions more accurately — at no cost.

3 Nov 2025

Study highlights bioengineered models as key to early cancer detection

Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it's more treatable and survival rates are highest.

3 Nov 2025

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

3 Nov 2025

Researchers develop a versatile tool for controlling gene activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

3 Nov 2025

Researchers identify new molecular switch involved in programmed cell death

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

3 Nov 2025

Healthy lifestyle habits plus GLP-1 RA drugs can improve heart health of people with Type 2 diabetes

People with Type 2 diabetes who combined healthy lifestyle habits with GLP-1 receptor agonist (GLP-1 RA) medications had a greater reduction in risk of major adverse cardiovascular events, including heart attack, stroke or cardiovascular disease death, compared to people only taking the medication, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Sock hops and concerts: How some places spent opioid settlement cash

Officials in Irvington, New Jersey, had an idea. To raise awareness about the dangers of opioid use and addiction, the township could host concerts with popular R&B artists like Q Parker and Musiq Soulchild.

3 Nov 2025

Research shows citrus and grape compounds may protect against type 2 diabetes

A six-month clinical trial found that a supplement combining citrus and grape extracts, hesperidin, and chromium significantly reduced fasting blood glucose in prediabetic adults. Participants also saw improved cholesterol and triglyceride levels, returning many to normal metabolic health.

2 Nov 2025

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

31 Oct 2025

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Genetic insights into vestibular system damage from ototoxic drugs

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

31 Oct 2025

Novel approaches to understanding EETs and cardiovascular disease

Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central mediators of inflammation, fever, and pain.

31 Oct 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

At the hollow in Florida, the ‘medical freedom’ movement finds its base camp

MAGA and MAHA are happily married in Florida, and nowhere more at home than in Sarasota County, where on a humid October night a crowd of several hundred gathered to honor state Surgeon General Joseph Ladapo, his wife, and an unlicensed Canadian radiologist who treats cancer with horse paste.

31 Oct 2025

Researchers to study the economics of substance use disorder treatments with $4 million NIDA grant

A team led by Weill Cornell Medicine and University of Miami's Miller School of Medicine investigators has been awarded a five-year, $4 million grant from the National Institute on Drug Abuse (NIDA) for health economics research.

30 Oct 2025

New method yields up to twice as many therapeutic myogenic cells as previous protocols

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

30 Oct 2025

New evidence-based points to consider and consensus definitions for people with psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have disease that is difficult to manage (D2M) or does not respond to treatment. EULAR - The European Alliance of Associations for Rheumatology - has released new evidence-based points to consider and consensus definitions for these groups.

30 Oct 2025

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Drugs News and Research

New approach harnesses tumor's own machinery to produce immune-stimulating molecules

Smartphones match traditional methods in monitoring patients with muscular dystrophy

Study highlights bioengineered models as key to early cancer detection

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

Researchers develop a versatile tool for controlling gene activity

Researchers identify new molecular switch involved in programmed cell death

Healthy lifestyle habits plus GLP-1 RA drugs can improve heart health of people with Type 2 diabetes

Sock hops and concerts: How some places spent opioid settlement cash

Research shows citrus and grape compounds may protect against type 2 diabetes

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Pioneering technology enables scalable production of human kidney organoids

Lab-grown organoid offers a platform to study how liver scarring develops

Genetic insights into vestibular system damage from ototoxic drugs

Novel approaches to understanding EETs and cardiovascular disease

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

At the hollow in Florida, the ‘medical freedom’ movement finds its base camp

Researchers to study the economics of substance use disorder treatments with $4 million NIDA grant

New method yields up to twice as many therapeutic myogenic cells as previous protocols

New evidence-based points to consider and consensus definitions for people with psoriatic arthritis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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