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Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Trump’s idea for health accounts has been tried. Millions of patients have ended up in debt.

Sarah Monroe once had a relatively comfortable middle-class life. She and her family lived in a neatly landscaped neighborhood near Cleveland. They had a six-figure income and health insurance. Then, four years ago, when Monroe was pregnant with twin girls, something started to feel off.

9 Dec 2025

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

SARS‑CoV‑2, the virus that causes COVID-19, continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid.

8 Dec 2025

Insufficient sleep may decrease life expectancy

A good night's sleep is more than a luxury: New research from Oregon Health & Science University suggests that insufficient sleep may shorten your life.

8 Dec 2025

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

An international research team led by Professor Marc-Emmanuel Dumas at Imperial College London & CNRS together with Prof. Patrice Cani (Imperial & University of Louvain, UCLouvain), Dr. Dominique Gauguier (Imperial & INSERM, Paris) and Prof. Peter Liu (University of Ottawa Heart Institute) has uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine (TMA).

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

Study reveals the hidden toll of sudden cardiac death in type 1 and type 2 diabetes

A Danish nationwide study found that people with type 1 and type 2 diabetes have markedly higher rates of sudden cardiac death than the general population, especially at younger ages. At age 30, people with diabetes lose many years of life, with several of those years specifically attributable to sudden cardiac death.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

In RFK Jr.’s upside-down world of vaccines, panel votes to end hepatitis B shot at birth

Recent weeks have brought good news about vaccines, with studies indicating that flu vaccination reduces heart disease, shingles vaccines can prevent or slow dementia, and a single human papilloma virus shot protects a girl from cervical cancer for the rest of her life.

5 Dec 2025

New Lancet series blends social science with medicine to tackle global health inequities

Can doctors in California learn from a patient who was bounced from one specialist to another in Japan? Can clinicians in London take lessons from a patient seeking asylum while suffering a medical emergency at the U.S.-Mexico border? Can doctors treating refugees in Africa inform health policy around the world?

5 Dec 2025

CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

5 Dec 2025

Genetic variant linked to higher heart failure risk in children with myocarditis

A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure.

5 Dec 2025

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

In a study funded by the National Heart, Lung, and Blood Institute, new research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is the most effective strategy for improving health.

5 Dec 2025

Early reversal of unhealthy weight can protect the heart from higher childhood BMI

Overweight as a child is not necessarily a risk factor for heart attack later in life. If weight is normalized before adulthood, the heart seems unaffected by the higher childhood BMI, according to a study conducted at the University of Gothenburg.

5 Dec 2025

Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.

4 Dec 2025

Breakthrough in imaging speed moves portable stroke diagnosis closer to reality

When someone walks into an emergency room with symptoms of a stroke, every second matters. But today, diagnosing the type of stroke, the life-or-death distinction between a clot and a bleed, requires large, stationary machines like CT scanners that may not be available everywhere.

4 Dec 2025

Psychosocial stress in women linked to early signs of heart tissue changes

Women who report high levels of psychosocial stress, such as from caregiving and lack of emotional support, show signs of early heart tissue changes associated with cardiovascular disease – an association not observed in men, a new study reveals.

4 Dec 2025

Chronic kidney disease accelerates cognitive decline through heart-brain pathways

A new study published in the American Journal of Physiology - Heart and Circulatory Physiology reveals that chronic kidney disease (CKD) accelerates cognitive decline through interconnected damage to the heart and brain-and that these pathways differ markedly between men and women.

4 Dec 2025

Rising nighttime heat is linked to shorter and more disrupted sleep

Higher nighttime temperatures are linked to shorter sleep times and lower sleep quality, especially for people with chronic health conditions, lower socioeconomic status, or those living on the West Coast, according to a new USC study.

4 Dec 2025

Long-term air pollution exposure linked to more advanced coronary artery disease

Long-term exposure to common air pollutants is associated with more advanced coronary artery disease-with notable differences between women and men-according to a large-scale study of more than 11,000 adults being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2025

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Heart News and Research

Online reference library provides a more accurate picture of drug exposure

Trump’s idea for health accounts has been tried. Millions of patients have ended up in debt.

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

Insufficient sleep may decrease life expectancy

Researchers discover a surprising ally in the fight against insulin resistance and type 2 diabetes

JAX wins $30 million contract to create computational "digital twins" of the human heart

Study reveals the hidden toll of sudden cardiac death in type 1 and type 2 diabetes

Most sickle cell patients face long delays for recommended pain relief, study shows

In RFK Jr.’s upside-down world of vaccines, panel votes to end hepatitis B shot at birth

New Lancet series blends social science with medicine to tackle global health inequities

CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Genetic variant linked to higher heart failure risk in children with myocarditis

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

Early reversal of unhealthy weight can protect the heart from higher childhood BMI

Bacterial enzyme linked to heart complications in pneumonia

Breakthrough in imaging speed moves portable stroke diagnosis closer to reality

Psychosocial stress in women linked to early signs of heart tissue changes

Chronic kidney disease accelerates cognitive decline through heart-brain pathways

Rising nighttime heat is linked to shorter and more disrupted sleep

Long-term air pollution exposure linked to more advanced coronary artery disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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