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Clot-busting drug tenecteplase shows promising results for stroke recovery

For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later than the drug alteplase, according to a meta-analysis published in the October 16, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

16 Oct 2024

Researchers uncover distinct cell vulnerabilities in Alzheimer’s progression with novel multiomics approach

Researchers used single-cell and spatial genomics to map cell-type-specific changes in the middle temporal gyrus, identifying distinct disease phases in Alzheimer’s progression.

16 Oct 2024

Alleo and Ubiquigent enter AI-driven strategic partnership to accelerate DUB-focused drug discovery

Ubiquigent Limited (“Ubiquigent”), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced a strategic partnership with Alleo Labs Corp. (“Alleo”), a pioneer in using artificial intelligence (AI) to develop new therapeutics for neurological diseases.

From Ubiquigent Limited 16 Oct 2024

Historical review reveals French contributions to depression research

In an era where mental health awareness is at the forefront of public discourse, a new historical review is shedding light on the often-overlooked French contributions to our understanding of depression.

16 Oct 2024

Research explores molecular mechanisms connecting TBI to Alzheimer's

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer's disease later in life.

15 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Understanding how the hippocampus discriminates social threat from safety

How do we distinguish threat from safety? It's a question important not just in our daily lives, but for human disorders linked with fear of others, such as social anxiety or post-traumatic stress disorder (PTSD).

15 Oct 2024

Understanding how aging impacts memory and learning

Our brains change as we age, and connections between the different parts of the brain become less efficient.

15 Oct 2024

Mayo Clinic scientists develop mini brain models to study Lewy body dementia

Lewy body dementia (LBD) is a progressive neurodegenerative disease that shares traits with both Parkinson's disease and Alzheimer's disease but can be more difficult to diagnose.

15 Oct 2024

Unique protein complex found to influence brain function and anxiety

Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of brain cell connectivity, as well as in specific cognitive behaviors.

12 Oct 2024

Innovative nanodiscs offer less invasive method for deep brain stimulation

Novel magnetic nanodiscs could provide a much less invasive way of stimulating parts of the brain, paving the way for stimulation therapies without implants or genetic modification, MIT researchers report.

12 Oct 2024

New study reveals the power of smile synchronization

Smiling during conversations creates warmth, making people feel more comfortable and connected. For example, a friendly smile when meeting someone new can ease nervousness. A smile can soften tension in a debate, showing respect among the participants despite disagreement.

12 Oct 2024

Bilingualism enhances brain connectivity and efficiency

Neuroplasticity is the brain's ability to build connections within itself, adapting to the surrounding environment.

10 Oct 2024

UVA research reveals nervous system's role in C. difficile infections

The portion of our nervous systems responsible for the "fight or flight" response can shape the severity of potentially deadly C. difficile infections, new research from the University of Virginia School of Medicine reveals.

10 Oct 2024

Neuroimaging study reveals structural brain differences in children with autism

There is new evidence that the cells responsible for communication in the brain may be structured differently in children with autism. Researchers at the Del Monte Institute for Neuroscience at the University of Rochester discovered that in some areas of the brain neuron density varies in children with autism when compared to the general population.

10 Oct 2024