Pathogen News and Research

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Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

1 Apr 2022

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Faculty from the Departments of Microbiology, Medicine Genetics and Genomic Sciences, and Pathology and Molecular Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai play key roles in a National Institutes of Health (NIH) program set up to provide a real-time risk assessment of variants of SARS-CoV-2, the virus that causes COVID-19. The program, called SARS-CoV-2 Assessment of Viral Evolution (SAVE) and described in a paper published March 31 in Nature, assesses how the variants might affect transmission, virulence, and resistance to both disease-induced (convalescent) and vaccine-induced immunity.

31 Mar 2022

How effective are household cleaning agents against SARS-CoV-2?

Researchers analyze commonly available household cleaning products to determine the most effective virucidal agent against SARS-CoV-2.

31 Mar 2022

New project launched to explore how GI microbiota may contribute to neurodegeneration

Alzheimer's disease (AD) is a type of dementia that affects memory, thinking and behavior. According to the Alzheimer's Association, an estimated 6.2 million Americans are living with this progressive neurologic disorder, and it is the sixth-leading cause of death in the U.S.

31 Mar 2022

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

When they're prepared for transport, apples and other fruits are often treated with a fungicide to prevent spoilage and extend shelf life.

31 Mar 2022

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

An exciting study recently published in the PNAS underscores the role of a well-established cytokine IL-13 in protecting our cells against SARS-CoV-2.

31 Mar 2022

Inconsistency in disease severity across SARS-CoV-2 variants

Researchers determine how the severity of successively dominant SARS-CoV-2 variants has changed since the beginning of the pandemic.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

29 Mar 2022

Newcastle disease virus-based trivalent vaccine found to be effective across SARS-CoV-2 variants in mice

In a new study, researchers tested the bi-, tri-, and tetravalent formulations of Newcastle disease virus (NDV)-based low-cost vaccine in mice.

29 Mar 2022

Virtual reality helps reduce COVID-19 vaccine hesitancy

A new study investigates whether intention for vaccination is increased by a gamified immersive VR experience that shows how community immunity works.

28 Mar 2022

Northwestern scientists continue to advance the understanding of COVID-19

As the COVID-19 pandemic enters its third year, Northwestern Medicine scientists continue to help advance the understanding of the disease and its impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research and highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.

28 Mar 2022

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Scientists compared the efficacy of the quantitative polymerase chain reaction method and immunohistochemistry in detecting SARS-CoV-2 in different human tissues.

25 Mar 2022

Researchers characterize vaccines for infectious bronchitis virus

A new study characterized the genetic and immunological aspects of the infectious bronchitis virus (IBV) vaccines commercially used in Korea.

25 Mar 2022

New model reveals how antibodies navigate pathogen surfaces like a child at play

A new study shows how antibodies select the antigens that they bind to, as they navigate the surface of pathogens like coronaviruses.

24 Mar 2022

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

24 Mar 2022

INRS professor developing a glycoconjugate vaccine for melioidosis

The threat from Melioidosis is real. The bacterium that causes this infectious multisymptom illness is resistant to antibiotics, making diagnosis and treatment more complex and resulting in a mortality rate of up to 50%.

24 Mar 2022

Discovery could help explain why certain infections are hard to get rid of

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections - such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

24 Mar 2022

Time-varying transmission heterogeneity of two significant beta-coronavirus epidemics in Hong Kong

Researchers demonstrated the daily variations in time-varying transmission heterogeneity through three COVID-19 epidemic waves of sustained local transmission in Hong Kong.

23 Mar 2022

Study investigates germinal center of antibody-mediated immunity against SARS-CoV-2

In a new study, researchers explored the germinal center of antibody-mediated immunity towards SARS-CoV-2.

23 Mar 2022

Pathogen News and Research

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

How effective are household cleaning agents against SARS-CoV-2?

New project launched to explore how GI microbiota may contribute to neurodegeneration

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

Inconsistency in disease severity across SARS-CoV-2 variants

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Newcastle disease virus-based trivalent vaccine found to be effective across SARS-CoV-2 variants in mice

Virtual reality helps reduce COVID-19 vaccine hesitancy

Northwestern scientists continue to advance the understanding of COVID-19

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Researchers characterize vaccines for infectious bronchitis virus

New model reveals how antibodies navigate pathogen surfaces like a child at play

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

INRS professor developing a glycoconjugate vaccine for melioidosis

Discovery could help explain why certain infections are hard to get rid of

Time-varying transmission heterogeneity of two significant beta-coronavirus epidemics in Hong Kong

Study investigates germinal center of antibody-mediated immunity against SARS-CoV-2

Best practices - optimize qPCR processes for pathogen detection eBook

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