Research News and Research

RSS

Poor sleep not a significant predictor of fibromyalgia pain intensity

Patients coping with the complex pain disorder fibromyalgia often have difficulty sleeping, and a new study published in The Journal of Pain reports that despite the negative quality of life implications, poor sleep is not a significant predictor of fibromyalgia pain intensity and duration.

23 Apr 2012

Nano-devices cross blood-brain barrier to deliver drug to treat cerebral palsy

A team of scientists from Johns Hopkins and elsewhere have developed nano-devices that successfully cross the brain-blood barrier and deliver a drug that tames brain-damaging inflammation in rabbits with cerebral palsy.

23 Apr 2012

Opiate addiction disorders associated with opioid-induced hyperalgesia

Patients with addictive disorders who take methadone or other opioid medications for pain will experience heightened sensitivity to pain, known as hyperalgesia, and new research published in The Journal of Pain shows that the condition does not improve over the course of treatment.

23 Apr 2012

Despite campaign rhetoric, Medicare deal may be possible

Meanwhile, though, some say Mitt Romney, if elected president, couldn't deliver on his promise to cut the budget without harming health care programs.

23 Apr 2012

Intrinsically disordered protein responsible for inactivating BK channel

Tiny pores, or channels, embedded in cell membranes are critical to the healthy functioning of cells. Charged atoms, or ions, move through these channels to generate the electrical signals that allow cells to communicate with one another.

23 Apr 2012

OncoSec reports positive interim data from ElectroChemotherapy Phase IV head and neck cancer study

OncoSec Medical Inc., which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumors, today announced positive interim analysis of data from 81 subjects in a Phase IV study of primary and locally recurrent squamous cell carcinoma of the head and neck (HNSCC) treated with OMS ElectroChemotherapy in Europe.

23 Apr 2012

First Edition: April 23, 2012

Today's headlines feature advance information about what the trustees who oversee Medicare and Social Security will say about the financial well-being of these massive programs when they release their annual report later today.

23 Apr 2012

APCR honors PAREXEL COO with Special Recognition Award

PAREXEL International Corporation, a leading global biopharmaceutical services organization, today announced that its Chief Operating Officer (COO), Mark A. Goldberg, M.D., was honored by the Academy of Physicians in Clinical Research.

From Parexel 23 Apr 2012

Herpes zoster vaccine safe and well tolerated: Study

The herpes zoster vaccine, also known as the shingles vaccine, is generally safe and well tolerated according to a Vaccine Safety Datalink study of 193,083 adults published online in the Journal of Internal Medicine.

23 Apr 2012

Mod5 yeast prion contributes to cell survival under environmental stress

One of the greatest mysterious in cellular biology has been given a new twist thanks to findings reported in Science. Researchers at the RIKEN Brain Science Institute show that prions, proteins that transmit heritable information without DNA or RNA, can contribute to drug resistance and cellular adaptation. Their discovery of a yeast prion with these properties demonstrates the active role of the prion conversion in cellular fitness adaptation, providing new insights into the potentially broader function of prions in living organisms.

23 Apr 2012

Sports medicine expert to present ‘Models of Injury Prevention’ at AMSSM conference

Roald Bahr, MD, PhD, will be presenting "Models of Injury Prevention" at the 21st American Medical Society for Sports Medicine Annual Meeting in Atlanta, GA on Saturday, April 21, 2012.

23 Apr 2012

AMSSM addresses strategies for injury prevention in young throwers

Tracy R. Ray, MD, delivered the Hough Memorial Lecture entitled "Pitch Counts: Can we prevent youth throwing injuries" at the 21st American Medical Society for Sports Medicine Annual Meeting in Atlanta, Ga. on Saturday, April 21, 2012.

23 Apr 2012

FDA strengthens and modernizes postmarket drug safety program

A strengthened and modernized postmarket drug safety program has resulted in a substantial improvement in the U.S. Food and Drug Administration's oversight of drugs once they reach the American public, according to a new report released today by the agency's Center for Drug Evaluation and Research.

23 Apr 2012

South African sports medicine expert to present at AMSSM annual meeting

South African sports medicine expert Martin Schwellnus, MD, PhD will be presenting "Born to Break Down? Genetics in Soft Tissue Injuries" at the 21st American Medical Society for Sports Medicine Annual Meeting in Atlanta, GA on April 22, 2012.

23 Apr 2012

BAMC/SAMMC researcher develops microemulsion vaccine carrier

A researcher at the Brooke Army Medical Center (BAMC)/San Antonio Military Medical Center (SAMMC) will present findings this week on a new potential vaccine carrier that he hopes will extend the shelf life of and aid in the stockpiling of critical vaccines.

23 Apr 2012

Moxonidine drug can improve heart function and reduce blood pressure

Heart failure is the most common cause of death throughout the world, typically the result of chronic high blood pressure, also known as hypertension. As a result, research efforts have focused on an array of approaches aimed at preventing and treating high blood pressure. Recently, Japanese researchers examined the utility of an anti-hypertensive drug, moxonidine, which acts on the imidazoline receptors in the cardiovascular center of the brainstem.

23 Apr 2012

Avocado oil protects against free radicals in mitochondria

Atmospheric oxygen facilitated the evolution and complexity of terrestrial organisms, including human beings, because it allowed nutrients to be used more efficiently by those organisms, which in turn were able to generate more energy. However, as we find out more about how oxygen molecules work inside the body, more attention is being paid to their not-so-good effects, and researchers are seeking ways to thwart them.

23 Apr 2012

Preliminary data hint at how neem extracts may stop replication of HIV virus

Tall, with dark-green pointy leaves, the neem tree of India is known as the "village pharmacy." As a child growing up in metropolitan New Delhi, Sonia Arora recalls on visits to rural areas seeing villagers using neem bark to clean their teeth. Arora's childhood memories have developed into a scientific fascination with natural products and their power to cure illnesses.

23 Apr 2012

APS honors MCW professor with Henry Pickering Bowditch Lecture Award

High blood pressure, or hypertension, is a major problem worldwide, with the latest estimates suggesting that a billion people across the globe may have this condition. Hypertension not only takes an enormous cost on health and wellbeing, but it also exacts an expensive financial toll. Complications from this condition including kidney disease, and its resulting treatments, such as long-term dialysis and kidney transplant, are some of the costliest conditions the American health care system must contend with.

23 Apr 2012

Study shows how cocaine changes the shape and size of neuron rewards in mouse model

New research from Mount Sinai Medical Center in New York reveals that repeated exposure to cocaine decreases the activity of a protein necessary for normal functioning of the brain's reward system, thus enhancing the reward for cocaine use, which leads to addiction. Investigators were also able to block the ability of repeated cocaine exposure, to induce addiction.

23 Apr 2012