Immune System News and Research

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Autoantibodies are detected years before symptom onset in patients with Sjögren syndrome

Autoantibodies are present many years before symptom onset in patients with primary Sjögren syndrome, an autoimmune disease, according to a Research Letter published in the November 6 issue of JAMA.

6 Nov 2013

Researchers link species of intestinal bacteria to onset of rheumatoid arthritis

Researchers have linked a species of intestinal bacteria known as Prevotella copri to the onset of rheumatoid arthritis, the first demonstration in humans that the chronic inflammatory joint disease may be mediated in part by specific intestinal bacteria.

6 Nov 2013

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Kathleen Sakamoto, MD, PhD, and Irving Weissman, MD, of the Stanford University School of Medicine and Lucile Packard Children's Hospital, have received a $1.37 million grant from CureSearch for Children's Cancer to research the effects of an antibody that has been shown to be effective against human cancers in animal models.

5 Nov 2013

Study: Clinicians' decision making could be affected by method of conception

Parents who conceive through assisted reproductive technologies are likely to receive different medical advice in relation to prenatal testing than those who conceive naturally, academics have suggested.

5 Nov 2013

Fewer doses of HPV vaccine may confer necessary long-term protection against new infection

NCI scientists report that two doses of a human papillomavirus (HPV) vaccine, trademarked as Cervarix, resulted in similar serum antibody levels against two of the most carcinogenic types of HPV (16 and 18), compared to a standard three dose regimen.

5 Nov 2013

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

Leicester scientists have mapped the "bouquet-like" structure of a key part of the body's immune system responsible for neutralising bacteria and viruses.

5 Nov 2013

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Biothera announced today top-line results from its Phase 2b clinical trial in non-small cell lung cancer (NSCLC) that evaluated its immunotherapeutic drug candidate, Imprime PGG®, with cetuximab (Erbitux®), carboplatin and paclitaxel compared with the monoclonal antibody and chemotherapy combination alone.

5 Nov 2013

Paracetamol, ibuprofen or combination of both provide no advantage for respiratory tract infections

Questions have been raised about the advice given to patients with a cold and sore throat, in research published in the British Medical Journal.

4 Nov 2013

JDRF partners with Pfizer's CTI to support diabetes research

JDRF, the leading global organization funding type 1 diabetes research, announced today a partnership with Pfizer's Centers for Therapeutic Innovation to support the development and translation of promising diabetes research.

4 Nov 2013

Probiotics may help keep bad germs at bay

Microbes are everywhere - thousands of species are in your mouth, and thousands are in a glass of tap water. The ones in your mouth are mostly harmless - as long as you brush and floss so they don't form a biofilm that allows gum disease a path into the blood stream.

4 Nov 2013

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

GeNeuro announced today that its GNbAC1 humanized monoclonal antibody was found to have a very good safety profile when administered to patients with relapsing and progressive forms of Multiple Sclerosis as part of a Phase 2a study.

4 Nov 2013

Patients with mutation in gene encoding CX3CR1 at higher risk of candidiasis

Candida albicans is one of the leading causes of hospital-acquired infections in immune compromised patients. The risk of both developing candidiasis and the clinical outcome of infection is variable among patients, and the host-dependent factors that contribute to patient susceptibility to C. albicans infection are poorly understood.

4 Nov 2013

Research roundup: States struggling with Medicaid expansion "complex issues"

We conducted a secondary analysis of data (2005 to 2010) from the Medical Expenditure Panel Survey. ... Comparisons were made between 2 groups to reflect likely movements in insurance status after the Patient Protection and Affordable Care Act implementation: (1) the uninsured who will be Medicaid eligible afterward versus Medicaid insured, and (2) the uninsured who will be Medicaid ineligible afterward versus the privately insured. ...

4 Nov 2013

Research findings offer new therapeutic paradigm for periodontal disease

The red, swollen and painful gums and bone destruction of periodontal disease could be effectively treated by beckoning the right kind of immune system cells to the inflamed tissues, according to a new animal study conducted by researchers at the University of Pittsburgh.

4 Nov 2013

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Nov 2013

SRI to expand current preclinical molecular imaging capabilities with MILabs VECTor+ system

MILabs is pleased to announce that Sunnybrook Research Institute, the research arm of the Sunnybrook Health Sciences Centre, located in Toronto, Canada will install a MILabs VECTor+ system to expand their current preclinical molecular imaging capabilities.

4 Nov 2013

Experimental drug effective in treating patients with non-small cell lung cancer

An experimental cancer drug that has shown promise in the treatment of melanoma has also shown early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death among men and women worldwide.

4 Nov 2013

Taking care of your gums by brushing could help hold heart disease at bay

Taking care of your gums by brushing, flossing, and regular dental visits could help hold heart disease at bay. Researchers at Columbia University's Mailman School of Public Health have shown for the first time that as gum health improves, progression of atherosclerosis slows to a clinically significant degree. Findings appear online in the Journal of the American Heart Association.

3 Nov 2013

Interim data from Phase 1B trial of an investigational anti-PD-1 immunotherapy in patients with previously-treated NSCLC announced by Merck

Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced the presentation of interim data from a Phase 1B trial (PN001) evaluating MK-3475, an investigational anti-PD-1 immunotherapy, in patients with previously-treated non-small cell lung cancer (NSCLC). The data were presented today by Dr. Edward Garon, Director of Thoracic Oncology, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, at the 15th World Conference on Lung Cancer in Sydney, Australia (Abstract #2416).

31 Oct 2013

VG Life Sciences' peptide awarded US patent for HIV treatment

The United States Patent and Trademark Office has issued on October 15, 2013 Patent No.: US 8,557,764 covering the VG Life Sciences' peptide VG1177 for treating HIV infection.

31 Oct 2013

Immune System News and Research

Autoantibodies are detected years before symptom onset in patients with Sjögren syndrome

Researchers link species of intestinal bacteria to onset of rheumatoid arthritis

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Study: Clinicians' decision making could be affected by method of conception

Fewer doses of HPV vaccine may confer necessary long-term protection against new infection

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

Biothera announces top-line results from Phase 2b clinical trial in non-small cell lung cancer

Paracetamol, ibuprofen or combination of both provide no advantage for respiratory tract infections

JDRF partners with Pfizer's CTI to support diabetes research

Probiotics may help keep bad germs at bay

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

Patients with mutation in gene encoding CX3CR1 at higher risk of candidiasis

Research roundup: States struggling with Medicaid expansion "complex issues"

Research findings offer new therapeutic paradigm for periodontal disease

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

SRI to expand current preclinical molecular imaging capabilities with MILabs VECTor+ system

Experimental drug effective in treating patients with non-small cell lung cancer

Taking care of your gums by brushing could help hold heart disease at bay

Interim data from Phase 1B trial of an investigational anti-PD-1 immunotherapy in patients with previously-treated NSCLC announced by Merck

VG Life Sciences' peptide awarded US patent for HIV treatment

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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