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Medical journals facing raft of ethical, transparency challenges

The New York Times, Connecticut Mirror and MedPage Today examine how prominent journals are handling questions about their independence or integrity.

18 Apr 2012

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA.

18 Apr 2012

Excessive alcohol use associated with lower self-reporting of maturity

Tipping back one too many cocktails during an individual's early 20s doesn't correlate to a personal sense of immaturity; however if this habit doesn't stop as they reach age 30, young adults can feel psychologically underdeveloped, according to a University of Missouri study. Helping young adults acknowledge their mental impulse to "sober up" as they mature can improve substance abuse intervention programs.

18 Apr 2012

U.S. Chamber of Commerce finds small business owners wary of health law regs

The survey finds that the regulations rank at the top of small business owners' concerns. In other news, the National Journal examines the future of accountable care organizations.

18 Apr 2012

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.

18 Apr 2012

IMRT facilitates radiation dose escalation without compromising long-term morbidity for prostate cancer

In an analysis of three different types of radiation therapy used to treat localized prostate cancer, compared with conformal radiation therapy, intensity-modulated radiation therapy (IMRT) was associated with fewer diagnoses of gastrointestinal adverse effects, hip fractures, and receipt of additional cancer treatments but more erectile dysfunction, while proton therapy was associated with more gastrointestinal adverse effects than IMRT.

18 Apr 2012

FDA to regulate smartphone medical applications; Companies to enter $4 billion insurance exchange market

An onslaught of mobile health technology has forced an arranged marriage between smartphone app makers and the Food and Drug Administration -- because someone had to regulate them. There's just one problem: Many of the tech wizards aren't used to FDA supervision. And now, both sides are struggling to figure out how to live with each other.

18 Apr 2012

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Scientists who developed a technology for identifying and targeting unique protein receptor ZIP Codes on the cellular surface have found a way to penetrate the outer membrane and deliver engineered particles - called iPhage - to organelles inside the cell.

18 Apr 2012

Study explains why women are more prone to knee injuries than men

Women are more prone to knee injuries than men, and the findings of a new study suggest this may involve more than just differences in muscular and skeletal structure - it shows that males and females also differ in the way they transmit the nerve impulses that control muscle force.

18 Apr 2012

Patients, health care professionals invited to improve comparative clinical effectiveness research

More involvement by patients, clinicians and others in the health care community in developing comparative clinical effectiveness research studies will make such studies far more useful in clinical decision-making, according to the Patient-Centered Outcomes Research Institute, in an article published in the April 18 issue of JAMA, a theme issue on comparative effectiveness research.

18 Apr 2012

Viewpoints: White House makes its case on cutting Medicare but one critic isn't buying the 'shared sacrifice'

These officials say the administration has also made modest but important progress in controlling Medicare spending, the biggest debt driver. The budget raises some Medicare premiums on high-income retirees and increases some deductibles.

18 Apr 2012

Though costly, helicopter trips save lives of seriously injured trauma patients

Seriously injured trauma patients transported to hospitals by helicopter are 16 percent more likely to survive than similarly injured patients brought in by ground ambulance, new Johns Hopkins research shows.

18 Apr 2012

Study sheds light on why ageing makes us more susceptible to gum disease

New research from Queen Mary, University of London in collaboration with research groups in the USA sheds light on why gum disease can become more common with old age.

18 Apr 2012

IMRT better than CRT for treatment of localized prostate cancer

A treatment for localized prostate cancer known as Intensity Modulated Radiation Therapy (IMRT) is better than conventional conformal radiation therapy (CRT) for reducing certain side effects and preventing cancer recurrence, according to a study published in the April 18, 2012 issue of the Journal of the American Medical Association.

18 Apr 2012

Bevacizumab added to chemotherapy for NSCLC does not improve survival in elderly patients

Adding the drug bevacizumab (Avastin) to the standard chemotherapy regimen for non-small cell lung cancer (NSCLC) - an approach approved by the FDA in 2006 - did not lead to significantly increase survival rates for patients over the age of 65 enrolled in Medicare, a new study by Dana-Farber Cancer Institute researchers has found.

18 Apr 2012

New Malawi President Joyce Banda offers women 'hope for a better future,' but donor support necessary

"On Saturday April 7th, Joyce Banda became Africa's second sitting female president," Lyndon Haviland, a senior strategy fellow at Aspen Global Health and Development, notes in this AlertNet opinion piece, writing, "President Banda offers women in Africa a second chance to experience women's leadership (Liberia President Ellen Johnson Sirleaf's recent Nobel Peace Prize demonstrates what can happen when women lead) -- and for the women of Malawi that cannot come soon enough."

18 Apr 2012

Research News and Research

Medical journals facing raft of ethical, transparency challenges

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Excessive alcohol use associated with lower self-reporting of maturity

U.S. Chamber of Commerce finds small business owners wary of health law regs

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

IMRT facilitates radiation dose escalation without compromising long-term morbidity for prostate cancer

FDA to regulate smartphone medical applications; Companies to enter $4 billion insurance exchange market

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Study explains why women are more prone to knee injuries than men

Patients, health care professionals invited to improve comparative clinical effectiveness research

Viewpoints: White House makes its case on cutting Medicare but one critic isn't buying the 'shared sacrifice'

Though costly, helicopter trips save lives of seriously injured trauma patients

Study sheds light on why ageing makes us more susceptible to gum disease

IMRT better than CRT for treatment of localized prostate cancer

Bevacizumab added to chemotherapy for NSCLC does not improve survival in elderly patients

New Malawi President Joyce Banda offers women 'hope for a better future,' but donor support necessary

Failure rate of PIP silicone breast implants could be as high as 33.8%

No added HIV risk with hormonal contraceptives

New research unable to find either positive or negative impact of WIC on infant health

Large childhood immunization campaign begins in Haiti, with support from U.S., other international partners

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