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New York Times examines global response to Haiti's cholera epidemic

The New York Times examines the global response to Haiti's cholera epidemic, writing that while "[m]any health officials consider the cholera response 'pretty remarkable,' as John Vertefeuille, the Centers for Disease Control and Prevention's director in Haiti, said ... [o]thers ... believe the bar for success was set too low and more lives could have been saved."

2 Apr 2012

Novel tetracyclines with improved potency, efficacy against contemporary P. aeruginosa isolates

Tetraphase Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on next-generation antibiotics, announced today that it is presenting new results from studies that demonstrate the improved potency and pharmacokinetics of several of its newest discovery-stage tetracycline analogs.

2 Apr 2012

Study sheds light on cellular mechanisms involved in flu resistance

Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system.

2 Apr 2012

New diagnostic test for Trichomonas vaginalis

Medical Diagnostic Laboratories, L.L.C. is a CLIA certified infectious disease laboratory which specializes in high-complexity, state-of-the-art, automated DNA-based molecular analyses.

2 Apr 2012

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

Nektar Therapeutics announced today that the first subjects were dosed last week in a Phase 1 clinical study to evaluate the pharmacokinetics and safety of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate.

2 Apr 2012

RainDance introduces new panel for cancer mutation screening

RainDance Technologies, Inc., the Digital Biology company, today announced the worldwide availability of its new panel for cancer mutation screening research using any next-generation sequencing (NGS) system.

2 Apr 2012

Life Technologies expands TaqMan Mutation Detection Assays

Life Technologies Corporation today announced the expansion to its TaqMan Mutation Detection Assays -- highly sensitive and novel molecular analysis research tools designed to detect an additional 241 of the most common mutations in 21 cancer genes.

2 Apr 2012

First Edition: April 2, 2012

Today's headlines offer more analysis of what could become of the Supreme Courts consideration of the health law.

2 Apr 2012

Inovio awarded U.S. DOD grant to advance non-invasive surface electroporation delivery device

Inovio Pharmaceuticals, Inc. announced today it has received a U.S. Department of Defense Small Business Innovation Research Grant to advance the development of a low-cost, non-invasive surface electroporation (EP) delivery device and test its utility in combination with Inovio's novel synthetic DNA vaccines against viruses with bioterrorism potential, including hanta, puumala, arenavirus and pandemic influenza.

2 Apr 2012

Clinical data for cabozantinib to be presented at ASCO annual meeting

Exelixis, Inc. announced today that its lead compound, cabozantinib, will be the subject of nine separate data presentations at the upcoming Annual Meeting of the American Society of Clinical Oncology.

2 Apr 2012

Ingenuity iReport for Real-Time PCR optimized for TaqMan Gene Expression Assays

Ingenuity Systems, a leading provider of information and analysis solutions for life science researchers, and Life Technologies Corporation today announced Ingenuity iReport for Real-Time PCR optimized for TaqMan Gene Expression Assays.

2 Apr 2012

ProteinSimple introduces Sally Western Blot

ProteinSimple today introduced Sally as the next member of the revolutionary Simple Western product family. Sally eliminates a critical bottleneck in large-scale protein research and biopharmaceutical development – manual Western Blot analysis. With Sally, researchers can perform 96 Simple Westerns in a single automated experiment.

From ProteinSimple 2 Apr 2012

Phage therapy can combat Pseudomonas infections in CF patients

Scientists in Cork have identified a novel therapy for the bacteria which cause infections in cystic fibrosis patients.

2 Apr 2012

Leicester Kidney Exercise Team shortlisted for BMJ award

A team of researchers from the University of Leicester, Leicester's Hospitals and the University of Loughborough are in the running for a prestigious medical award.

2 Apr 2012

TGen to present TNBC study at AACR 2012 annual meeting

Because cases of Triple-Negative Breast Cancer (TNBC) are so genetically different, whole-genome sequencing is needed to detect the subtle molecular differences that might point to specific treatments for individual patients.

2 Apr 2012

Allowing the heart to rest can reverse structural changes in myocytes after heart failure

Structural changes in heart muscle cells after heart failure can be reversed by allowing the heart to rest, according to research at Imperial College London. Findings from a study in rats published today in the European Journal of Heart Failure show that the condition's effects on heart muscle cells are not permanent, as has generally been thought. The discovery could open the door to new treatment strategies.

2 Apr 2012

Scientists use DNA sequencing to identify 'driver' mutations in cancer

Scientists at Washington University School of Medicine in St. Louis are using powerful DNA sequencing technology not only to identify mutations at the root of a patient's tumor - considered key to personalizing cancer treatment - but to map the genetic evolution of disease and monitor response to treatment.

2 Apr 2012

Elekta receives clearance to CE mark Agility device

Elekta announced today it has received clearance to CE mark Agility, a revolutionary beam-shaping device integrated into the head of a linear accelerator (linac). Patients and clinics will benefit from the speed and reliability of this new MLC design.

From Elekta 2 Apr 2012

RT3D may boost effects of two standard chemotherapy drugs in head and neck cancer patients

A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published today in Clinical Cancer Research.

2 Apr 2012

Twins and mothers with poor nutrition more likely to develop obesity, type 2 diabetes

If you're expecting, this might make you feel a little better about reaching for that pint of ice cream: New research published online in the FASEB Journal suggests that twins, and babies of mothers who diet around the time of conception and in early pregnancy, may have an increased risk of obesity and type 2 diabetes throughout their lives.

2 Apr 2012

Research News and Research

New York Times examines global response to Haiti's cholera epidemic

Novel tetracyclines with improved potency, efficacy against contemporary P. aeruginosa isolates

Study sheds light on cellular mechanisms involved in flu resistance

New diagnostic test for Trichomonas vaginalis

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

RainDance introduces new panel for cancer mutation screening

Life Technologies expands TaqMan Mutation Detection Assays

First Edition: April 2, 2012

Inovio awarded U.S. DOD grant to advance non-invasive surface electroporation delivery device

Clinical data for cabozantinib to be presented at ASCO annual meeting

Ingenuity iReport for Real-Time PCR optimized for TaqMan Gene Expression Assays

ProteinSimple introduces Sally Western Blot

Phage therapy can combat Pseudomonas infections in CF patients

Leicester Kidney Exercise Team shortlisted for BMJ award

TGen to present TNBC study at AACR 2012 annual meeting

Allowing the heart to rest can reverse structural changes in myocytes after heart failure

Scientists use DNA sequencing to identify 'driver' mutations in cancer

Elekta receives clearance to CE mark Agility device

RT3D may boost effects of two standard chemotherapy drugs in head and neck cancer patients

Twins and mothers with poor nutrition more likely to develop obesity, type 2 diabetes

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