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OncoSec to purchase $7.75M of securities in registered public offering

OncoSec Medical Incorporated, which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumor cancers, announced today that it has entered into definitive agreements with institutional investors to purchase $7.75 million of securities in a registered public offering.

26 Mar 2012

ETC-1002 drug reduces LDL cholesterol levels in hypercholesterolemic patients

Early data suggest ETC-1002, a drug that regulates lipid and carbohydrate metabolism, had a significant impact on cholesterol levels and improved factors believed to contribute to cardio-metabolic diseases, say researchers from the Methodist DeBakey Heart & Vascular Center, the Baylor College of Medicine, and Esperion Therapeutics, Inc., who are presenting their work at the 2012 American College of Cardiology Scientific Session in Chicago.

26 Mar 2012

Largest study to date to look at BMC therapy in patients with heart failure

Use of a patient's bone marrow cells for treating chronic ischemic heart failure did not result in improvement on most measures of heart function, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the American College of Cardiology's annual scientific sessions.

26 Mar 2012

New advance in ability to target and destroy certain cancer cells

An international team of scientists has announced a new advance in the ability to target and destroy certain cancer cells. A group led by the University of Leicester has shown that particular cancer cells are especially sensitive to a protein called p21. This protein usually forces normal and cancer cells to stop dividing but it was recently shown that in some cases it can also kill cancer cells.

26 Mar 2012

Women more likely to experience UI following vaginal delivery

Women are nearly three times more likely to experience urinary incontinence for more than 10 years following a vaginal delivery rather than a caesarean section, finds new research at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

26 Mar 2012

Periodontal treatment may decrease medical care costs for people with diabetes

Medical costs are lower for people with diabetes who receive treatment for gum disease, according to a study presented today to the American Association for Dental Research by Dr. Marjorie Jeffcoat of the University of Pennsylvania.

26 Mar 2012

High-fat, low-carb foods linked with increased risk of heart attack in obese people

High-fat, low-carb foods are a popular choice for dieters, but new laboratory research by University of Alabama at Birmingham cardiologists indicates these may be detrimental to the health of people who have ischemic cardiovascular disease or a predisposition to heart attacks.

26 Mar 2012

Unique clinic gives new lease of life – solves a family mystery

Isobel Dickinson, 62, of Wadsley, Sheffield, suffers from gluten ataxia – a neurological condition that can affect balance, co-ordination and speech. Until her diagnosis six years ago, little did she know that her difficulty balancing was being caused by sensitivity to gluten.

26 Mar 2012

Testosterone receptor may be a potential target for triple negative breast cancer

Could blocking a testosterone receptor lead to a new way to treat an aggressive form of breast cancer? That's a question researchers at Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) are exploring. Preliminary results of a Mayo Clinic - TGen collaborative study shows the testosterone receptor may be a potential target to attack in treating triple negative breast cancer (TNBC).

26 Mar 2012

Additional help does not improve success rates for smokers trying to quit

A major research trial to test whether extra support for smokers calling an NHS quitline - on top of what is already offered by the service - has found the additional help does not improve success rates for quitting the habit.

26 Mar 2012

Hi-tech 3D imaging may improve lives of chronic lung disease patients

Pioneering research in Southampton, using hi-tech 3D imaging, could improve the lives of those suffering from chronic lung disease.

26 Mar 2012

Epsilon Imaging introduces EchoInsight for cardiology community

Epsilon Imaging, Inc., an advanced visualization and analysis technologies provider for cardiology, today announced the debut of EchoInsight, a suite of applications for practical strain imaging and streamlined workflow in the clinical environment.

26 Mar 2012

USS more successful in removing palpable breast tumours

In a randomised controlled trial, researchers in The Netherlands have found that the use of ultrasound-guided surgery to remove tumours from women who have palpable breast cancer is much more successful than standard surgery in excising all the cancerous tissue while sparing as much healthy tissue as possible.

26 Mar 2012

Mutational profiling could determine which AML patients will benefit from dose-intensive chemotherapy

An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that analyzed mutations in 18 genes of 398 patients who had acute myeloid leukemia.

26 Mar 2012

Komen facing fundraising challenges, resignations of executives

U.S. breast cancer charity Susan G. Komen for the Cure is feeling a pinch on donations following a controversy over its funding for Planned Parenthood, a leading provider of birth-control and abortion services. A few of the group's flagship "Race for the Cure" fundraising events have failed to meet targets, a Komen spokeswoman said on Friday.

26 Mar 2012

Plouffe defends, Graham and Bachmann attack health law

As the Supreme Court takes up President Obama's health care law this week, the White House dispatched a top political aide to the Sunday talk shows to make the case for the law that will go far in defining Obama's legacy. "As it relates to the Supreme Court, we're confident that it's going to be upheld," senior Obama adviser David Plouffe said on ABC's This Week. ... In the meantime, Republican presidential candidates -- while hoping that the Supreme Court strikes down the law -- have vowed to repeal the law.

26 Mar 2012

Study reveals central role played by DBIRD protein complex in gene transcription

In a study published this week in the journal Nature, researchers at the University of Liège's GIGA Unit, together with English and German teams, reveal the central role played by a protein complex, unknown up to now, in gene transcription.

26 Mar 2012

Romney assails health law; Obama embraces 'Obamacare'

Mr. Romney used much of the event to mark the two-year anniversary of Democrats' national health care law, something he described as the "centerpiece" of President Barack Obama's failure as a president. "It's amazing how many things are wrong with it," Mr. Romney said. "I got a whole list here." That list did not include the law's requirement for individuals to buy health insurance, the subject of a closely watched Supreme Court case. While Mr. Romney was governor of Massachusetts, he signed a state law with a similar mandate.

26 Mar 2012

Court's review of Medicaid expansion could affect other federal programs

A major issue in the Supreme Court battle over the new health care law is whether Congress can force states to make a huge expansion of Medicaid, to add millions of low-income people to the rolls. States say the federal law is unconstitutionally coercive because all their Medicaid money would be at risk if they flout the new requirement. The states argument has implications that go far beyond health care.

26 Mar 2012

Angioplasty safe for MS patients with venous abnormalities

Researchers report that performing angioplasty (a treatment that involves temporarily inserting and blowing up a tiny balloon inside a clogged artery to help widen it) on veins in the neck and chest is safe—and may be an effective way to treat the venous abnormalities found in those with multiple sclerosis and provide symptom relief.

26 Mar 2012