Appetite News and Research

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New discovery may unlock development of next-generation sleeping pill

Insomnia is one of the major sleep problems with an estimated prevalence of 10% to 15% in the general population and 30% to 60% in the older population. Moreover, insomnia frequently co-occurs with a wide range of psychiatric disorders, including depression and anorexia.

26 Oct 2018

Jean Mayer Prize for Excellence in Nutrition Science and Policy awarded to individuals, organizations

The Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University has awarded the school's inaugural $100,000 Jean Mayer Prize for Excellence in Nutrition Science and Policy to two individuals and two organizations for their collective efforts to raise awareness of the risks of diet-related disease and advocacy for policies that champion better nutrition for younger generations.

23 Oct 2018

Study: Targeting specific genomic mutation in breast cancer improves survival

Targeting a common mutation in patients with hormone receptor positive (HR+) HER2 negative (HER2-) advanced breast cancer with the alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor alpelisib significantly improves progression-free survival, according to late-breaking results reported at ESMO 2018.

22 Oct 2018

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors

Deciphera Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on addressing key mechanisms of tumor drug resistance, announced the presentation today of updated preliminary results from its ongoing Phase 1 clinical study of DCC-2618, the company's broad-spectrum KIT and PDGFRα inhibitor, in patients with gastrointestinal stromal tumors as a proffered paper presentation at the European Society of Medical Oncology 2018 Congress in Munich, Germany.

22 Oct 2018

Incyte announces Phase 2 FIGHT-202 trial data in patients with cholangiocarcinoma

Incyte Corporation announces updated data from its ongoing Phase 2 FIGHT-202 trial evaluating pemigatinib (INCB54828), its selective fibroblast growth factor receptor (FGFR) inhibitor, in patients with advanced/metastatic or surgically unresectable cholangiocarcinoma (bile duct cancer) who failed at least one previous treatment.

22 Oct 2018

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

UC San Francisco researchers, in collaboration with the unique Brazilian Biobank for Aging Studies at the University of São Paulo, have shown that the earliest stages of the brain degeneration associated with Alzheimer's disease are linked to neuropsychiatric symptoms including anxiety, depression, loss of appetite, and sleep disturbances.

15 Oct 2018

Mast cells associated with allergies also play key role in survival, study reveals

In a University of California, Irvine-led study, researchers found evidence that mast cells, an important group of immune cells typically associated with allergies, actually enable the body to survive fasting or intense exercise.

12 Oct 2018

Appetite-suppressant drug reduces diabetes risk and increases remission rates of blood sugar

New research presented at this year's annual meeting of the European Association for the Study of Diabetes in Berlin, Germany, and published in The Lancet, shows that the appetite-suppressant drug lorcaserin decreases risk of developing diabetes and increases the rates of remission of high blood sugar.

4 Oct 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

Research findings could bring relief to millions of cancer patients undergoing chemotherapy

Patients undergoing cancer treatment confront a number of well-documented side effects.

26 Sep 2018

Breastfeeding could be important way to prevent childhood obesity, study finds

In the UK a quarter of two-to-five-year olds are overweight or obese. The World Health Organization classify childhood obesity as one of the most serious global health challenges for the 21st century and in 2016 estimated that more than 41 million children under five years old were overweight or obese worldwide.

26 Sep 2018

Study reveals connection between hunger and mood

It seems "hangry" isn't just a made-up term. University of Guelph researchers have revealed that the sudden drop in glucose we experience when we are hungry can impact our mood.

25 Sep 2018

China NMPA approves LENVIMA for treatment of unresectable hepatocellular carcinoma

Eisai Co., Ltd. and Merck & Co., Inc., Kenilworth N.J., U.S.A., known as MSD outside of the United States and Canada, announced that the China National Medical Products Administration approved the kinase inhibitor LENVIMA (lenvatinib) as a single agent for the treatment of patients with unresectable hepatocellular carcinoma who have not received prior systemic therapy.

24 Sep 2018

Study: Neural signal that urges to eat overpowers the one that says to stop

Almost everyone knows the feeling. You're at a restaurant or a holiday meal, and your stomach is telling you it's full, so logically you know you should stop eating.

21 Sep 2018

Chinese and German researchers to cooperate more closely in future for better food

Working together for better food: Chinese and German researchers want to cooperate more closely in the future.

18 Sep 2018

Zika virus vaccine shows promise for treatment of fatal glioblastoma

An international team of researchers has successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice.

18 Sep 2018

Two-minute bursts of in-class exercise breaks do not disrupt learning and teaching

As childhood obesity rates rise and physical education offerings dwindle, elementary schools keep searching for ways to incorporate the federally mandated half-hour of physical activity into the school day.

18 Sep 2018

Study: Social class determines how the unemployed describe food insecurity

"Cherry Blossom," a 39-year-old woman worked as a hotel breakfast bar hostess around the start of the "Great Recession." She lost her job, and three years later she was being interviewed to assess her struggles with her unemployment. She talked about her empty refrigerator.

17 Sep 2018

Cocaine-addicted rats show long-lasting increases in number of orexin neurons

A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction.

12 Sep 2018

Appetite News and Research

New discovery may unlock development of next-generation sleeping pill

Jean Mayer Prize for Excellence in Nutrition Science and Policy awarded to individuals, organizations

Study: Targeting specific genomic mutation in breast cancer improves survival

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors

Incyte announces Phase 2 FIGHT-202 trial data in patients with cholangiocarcinoma

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

Mast cells associated with allergies also play key role in survival, study reveals

Appetite-suppressant drug reduces diabetes risk and increases remission rates of blood sugar

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Research findings could bring relief to millions of cancer patients undergoing chemotherapy

Breastfeeding could be important way to prevent childhood obesity, study finds

Study reveals connection between hunger and mood

China NMPA approves LENVIMA for treatment of unresectable hepatocellular carcinoma

Study: Neural signal that urges to eat overpowers the one that says to stop

Chinese and German researchers to cooperate more closely in future for better food

Zika virus vaccine shows promise for treatment of fatal glioblastoma

Two-minute bursts of in-class exercise breaks do not disrupt learning and teaching

Study: Social class determines how the unemployed describe food insecurity

Cocaine-addicted rats show long-lasting increases in number of orexin neurons

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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