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Scientists unveil the hidden respiratory mechanisms of gut bacteria

Study explores the use of respiratory electron acceptors by diverse gut bacteria, revealing a novel type of anaerobic respiration linked to the gut metabolome and microbial energy metabolism.

8 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

8 Jan 2024

Genomic analysis of uncultured bacteria from patients identifies more than thirty new species

Unknown germs are a common occurrence in hospitals. Researchers at the University of Basel have spent many years collecting and analyzing them.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.

7 Jan 2024

University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader.

5 Jan 2024

Early pandemic sees drop in child UTI diagnoses, severity unchanged

A cohort study in JAMA Network Open found a decrease in urinary tract infection (UTI) diagnoses among children during the early COVID-19 pandemic without an increase in disease severity, suggesting a potential reduction in over- or misdiagnosis.

4 Jan 2024

Gonorrhea cases surge 64% post-COVID lockdown in England, highlighting unintended STI suppression

A study analyzing data from the Genitourinary Medicine Clinic Activity Dataset in England shows a 64% increase in gonorrhea diagnoses following the relaxation of COVID-19 restrictions, despite only a 5.6% increase in STI testing, suggesting that social distancing may have suppressed STI transmission.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against 'superbugs' such as MRSA, a new study shows.

3 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Radiographic study exposes ancient oral health of Swedish Vikings

Study examines dental health in a Swedish Viking Age population, revealing prevalent dental pathologies and unique oral practices through radiographic analysis.

2 Jan 2024

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Researchers receive two grants to study tuberculosis drug development

Weill Cornell Medicine researchers and the TB Drug Accelerator have received two grants totaling $6.8 million from the Bill & Melinda Gates Foundation to study tuberculosis (TB) drug development.

26 Dec 2023

New family of polymers can kill bacteria without inducing antibiotic resistance

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention.

22 Dec 2023

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed by researchers at São Paulo State University (UNESP) in Brazil and is reported in an article published in the journal Carbohydrate Polymers.

20 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

Bacterial News and Research

Scientists unveil the hidden respiratory mechanisms of gut bacteria

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Genomic analysis of uncultured bacteria from patients identifies more than thirty new species

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

Early pandemic sees drop in child UTI diagnoses, severity unchanged

Gonorrhea cases surge 64% post-COVID lockdown in England, highlighting unintended STI suppression

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

Gut microbiota linked to social anxiety behaviors

Radiographic study exposes ancient oral health of Swedish Vikings

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Common inflammation pathway turns anthrax toxin into killer

Researchers receive two grants to study tuberculosis drug development

New family of polymers can kill bacteria without inducing antibiotic resistance

Brazilian researchers create cutting-edge nanoparticle weapon against tuberculosis

First new antibiotic class in decades discovered using explainable AI platform

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