Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

New system for restoring damaged or lost knee cartilage tissue

Knee osteoarthritis affects 30 million people worldwide, causing pain and joint stiffness and in severe cases restricted mobility.

24 Apr 2007

Childhood sarcoma increases risk of blood clots

Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have determined that children and young adults with a form of cancer called sarcoma are at increased risk of having a thromboembolic event (TE) in their veins.

20 Apr 2007

Chondroitin for arthritis just doesn't work

According to Swiss researchers the dietary supplement chondroitin is no better than a placebo at easing the hip and knee pain of arthritis and they believe its use should be discouraged.

17 Apr 2007

dGEMRIC index as a predictor of cartilage mechanical stiffness

Can non-destructive MRI provide a measurement of cartilage function? The delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) index is highly correlated to mechanical stiffness, and, although not as good as a direct mechanical measurement, the index can be used as a predictive measure of stiffness.

11 Apr 2007

OHSU surgeon implants donated tissue allografts

Over the years, orthopedic surgeon Dennis Crawford, M.D., Ph.D., of Oregon Health & Science University found it difficult to obtain tissue for transplant to treat some of his patients suffering with severe joint disorders.

11 Apr 2007

Symphysiotomy could dramatically reduce maternal deaths

Teaching doctors in Africa a low-tech operation to cut the cartilage of the symphysis pubis could save the lives of women in obstructed labor and their babies, according to an Essay in the open access journal PLoS Medicine.

2 Apr 2007

Researchers identify gene for osteoporosis

Researchers report the identification of a gene that may play a role in susceptibility to osteoporosis, the crippling disease that leads to bone fractures, especially of the hip and spine.

31 Mar 2007

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Three-dimensional fabric "scaffold" to repair cartilage damage

Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells.

7 Feb 2007

Effect of physical activities on knee osteoarthritis in older adults

Regular exercise is recommended for middle-aged and older people, but the effect of exercise on the development of osteoarthritis (OA) in older people is unclear, especially if they are overweight.

31 Jan 2007

Statins slow the progression of aortic valve stenosis

The trial provides the first prospective clinical evidence that aortic valves have an active biology that can be targeted with medical therapy and contradicts research published in 2005 in the New England Journal of Medicine, which concluded statins did not halt the progression of aortic stenosis.

30 Jan 2007

Yaws disease re-emerging

Yaws, a disease which eats away at the skin, cartilage and bones of its victims (mostly children), is re- emerging in poor, rural and marginalized populations of Africa, Asia and South America.

28 Jan 2007

Cartilage discovery offers arthritis hope

Scientists have revealed the intricate structure of cartilage in what they hope will provide clues to how the crippling joint disease osteoarthritis might one day be treated.

From The University of Manchester 10 Jan 2007

Improved cell therapy for cartilage repair

Artificially cultured cartilage cells, grown outside of the body for reparing damaged tissue, prove to be different from original cartilage tissue.

2 Dec 2006

New treatment for lower back pain using patient's own stem cells

A University of Manchester researcher has developed a treatment for lower back pain using the patient's own stem cells, which could replace the use of strong painkillers or surgery that can cause debilitation, neither of which addresses the underlying cause.

From The University of Manchester 2 Dec 2006

Acupuncture and Turmeric could be viable treatment options for arthritis sufferers

People who suffer from osteoarthritis (OA) as a rule find it has to varying degrees an impact on their mobility and quality of life.

31 Oct 2006

Gene mutation explains type of brittle bone disease

A newly identified gene mutation helps explain a subset of cases of osteogenesis imperfecta (OI), or brittle bone disease, whose origin had until now remained mysterious.

20 Oct 2006

Arthrosurface launches new product for treatment of patello-femoral disease

Arthrosurface has received FDA clearance to launch its cartilage surface implant system for the treatment of patello-femoral disease.

15 Aug 2006

Atp7a determines a hierarchy of copper metabolism essential for notochord development

A new study reveals the timing of developmental events that critically depend on copper. While copper deficiency is rare in humans, the findings suggest that suboptimal copper metabolism might contribute to birth defects, according to the researchers.

8 Aug 2006

New faster magnetic resonance imaging (MRI) data-acquisition technique

A faster magnetic resonance imaging (MRI) data-acquisition technique will cut the time many patients spend in a cramped magnetic resonance scanner, yet deliver more precise 3-D images of their bodies.

26 Jul 2006