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Novel approach to immunotherapy design could pave the way for new brain cancer treatments

A novel approach to immunotherapy design could pave the way for new treatments for people with an aggressive form of brain cancer called glioblastoma.

10 May 2021

Damage to the white matter is more predictive of cognitive impairment after brain injury

A new University of Iowa study challenges the idea that gray matter (the neurons that form the cerebral cortex) is more important than white matter (the myelin covered axons that physically connect neuronal regions) when it comes to cognitive health and function.

7 May 2021

Absence of key gene causes severe hearing loss

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

7 May 2021

Moderate alcohol intake may be heart protective by reducing stress-related brain signals

Moderate alcohol intake--defined as no more than one alcoholic drink for women and two for men per day--has been associated with a lower risk of dying from cardiovascular disease when compared with individuals who abstain from drinking or partake in excessive drinking, according to a new study being presented at the American College of Cardiology's 70th Annual Scientific Session.

6 May 2021

Brain thinning in youth associated with psychosis

Subtle differences in the shape of the brain that are present in adolescence are associated with the development of psychosis, according to an international team led by neuroscientists at the University of Pittsburgh School of Medicine and Maastricht University in the Netherlands.

5 May 2021

Neuroimaging technology used to study how brain stimulation works for treatment of depression

Repetitive transcranial magnetic stimulation, or rTMS, was FDA approved in 2008 as a safe and effective noninvasive treatment for severe depression resistant to antidepressant medications. A small coil positioned near the scalp generates repetitive, pulsed magnetic waves that pass through the skull and stimulate brain cells to relieve symptoms of depression.

4 May 2021

Pioneering neural recordings lay the groundwork for personalized Parkinson's treatments

Pioneering neural recordings in patients with Parkinson's disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson's and other neurological disorders.

4 May 2021

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals.

30 Apr 2021

Researchers reveal how the brain may adapt to processing complex information

Human decision-making depends on the flexible processing of complex information, but how the brain may adapt processing to momentary task demands has remained unclear.

29 Apr 2021

Research provides deep and detailed look at how common anesthetic causes unconsciousness

In a uniquely deep and detailed look at how the commonly used anesthetic propofol causes unconsciousness, a collaboration of labs at The Picower Institute for Learning and Memory at MIT shows that as the drug takes hold in the brain, a wide swath of regions become coordinated by very slow rhythms that maintain a commensurately languid pace of neural activity.

27 Apr 2021

Neural implant can help monitor activity in multiple brain regions at the same time

How do different parts of the brain communicate with each other during learning and memory formation? A new study by researchers at the University of California San Diego takes a first step at answering this fundamental neuroscience question.

27 Apr 2021

Scientists receive prestigious grant to explore the effects of prior knowledge on learning and memory

The Canadian Institute of Health Research (CIHR) has awarded a team of scientists at Baycrest's Rotman Research Institute (RRI) a prestigious grant to determine why having prior knowledge on a topic affects how we learn new, related information as we age.

27 Apr 2021

New research unravels how the brain encodes social network structure

The brain encodes information about our relationships and the relationships between our friends using areas involved in spatial processing, according to new research published in JNeurosci.

22 Apr 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated with the overproduction of pro-inflammatory cytokines. This "cytokine storm" directly correlates with poor prognosis in this subgroup of patients.

21 Apr 2021

Cortex News and Research

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

Damage to the white matter is more predictive of cognitive impairment after brain injury

Absence of key gene causes severe hearing loss

Moderate alcohol intake may be heart protective by reducing stress-related brain signals

Brain thinning in youth associated with psychosis

Neuroimaging technology used to study how brain stimulation works for treatment of depression

Pioneering neural recordings lay the groundwork for personalized Parkinson's treatments

Study shows how tau spreads to four distinct patterns leading to different Alzheimer's symptoms

Researchers reveal how the brain may adapt to processing complex information

Research provides deep and detailed look at how common anesthetic causes unconsciousness

Neural implant can help monitor activity in multiple brain regions at the same time

Scientists receive prestigious grant to explore the effects of prior knowledge on learning and memory

New research unravels how the brain encodes social network structure

Study identifies how SARS-CoV-2 enters and infects the brain

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Protein-coding gene may worsen tau protein tangles associated with Alzheimer's

Markers of fear recall differ between sexes, but in a hormone-dependent manner

Researchers visualize fast brain signals from outside the skull

Study shows how alcohol may affect the brain, offers potential treatments for alcohol misuse

Children who snore regularly may have significant brain changes

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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