Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

60+ organizations to speak as the NASH Summit Boston returns

Hansonwade will present the 4th NASH Summit in Boston from May 4-7, 2020. For its anticipated return, the forum is set to widen its program and congregate over 350+ industry stakeholders for presentations from global regulatory agencies and leading biopharma.

From 4th NASH Summit Boston 29 Jan 2020

Deadly infection in cystic fibrosis could be curbed with combination medication

Researchers from Aston University and Birmingham Children’s Hospital have developed a new medication regimen that could successfully treat a bacterial infection that could prove fatal to patients with cystic fibrosis or bronchiectasis. The results of the new study were published in the latest issue of the journal Scientific Reports.

27 Jan 2020

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Toxoplasma gondii is best known as the parasite that may lurk in a cat's litter box. Nearly a third of the world's population is believed to live with a chronic Toxoplasma infection.

24 Jan 2020

New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

A new treatment developed by researchers at Aston University and Birmingham Children's Hospital has been found to completely kill a bacterial infection that can be deadly to cystic fibrosis patients.

24 Jan 2020

Researchers identify liver fibrosis ‘off switch’ in mice

Chronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue.

23 Jan 2020

Lung microbes could help predict outcomes in the seriously ill

A new study published in the American Journal of Respiratory and Critical Care Medicine shows that recording the way the organisms living within the lungs change in type and numbers could reflect the response of the critically ill patient to medical care. Though changes in the lung microbiome have been known to exist even before this study, this research shows the clinical importance of this test.

23 Jan 2020

Lung microbiome of critically ill patients is predictive of clinical outcomes

Changes in the lung microbiome may help predict how well critically ill patients will respond to care, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

21 Jan 2020

Cardiac and visual degeneration compensated by taurine supplement

Our genome consists of 20,000 genes, all of which may be capable of triggering disease. It is estimated that there are 7,000 unknown genes that cause recessive genetic diseases resulting from mutations in two copies of a gene that have been inherited from each parent.

21 Jan 2020

Magnetic nanomaterials may become the basis for new approach to treating liver fibrosis

A team of scientists from Immanuel Kant Baltic Federal University together with their colleagues from NUST MISiS and RWTH Aachen University (Germany) compared different treatments against liver fibrosis and published the results of their study in the Cells journal.

21 Jan 2020

Study finds new strategies for developing cancer drug

After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are published in the scientific journal Nature Communications, open for new strategies to treat different types of cancer.

21 Jan 2020

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

Enterprise Therapeutics Ltd, a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering with respiratory disease, today announced the publication of its first peer-reviewed paper.

21 Jan 2020

Study determines prevalence of fatty liver disease and fibrosis among young adults in the UK

One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today [15 January] has found.

16 Jan 2020

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina, has taken a vital step toward commercializing an innovative diagnostic technique that could better predict kidney transplant success in patients with focal segmental glomerulosclerosis (FSGS), a kidney disease that often leads to end-stage renal failure.

14 Jan 2020

Orthopaedic Research UK announces £140,000 investment in biotech startup

Orthopaedic Research UK has announced that biotech startup, Renovos, will receive the first investment from its newly launched the Ronald Furlong Fund, a partnership between ORUK and HS., established this year in memory of the charity’s founder.

14 Jan 2020

Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

Boehringer Ingelheim and Enleofen Bio Pte. Ltd. announced today the acquisition of worldwide exclusive rights to Enleofen’s preclinical interleukin-11 (IL-11) platform by Boehringer Ingelheim to develop first-in-class therapies across a broad range of fibro-inflammatory diseases.

From Boehringer Ingelheim International GmbH 14 Jan 2020

Boston researchers develop novel approach to generate intestinal organoids in vitro

Boston researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system.

11 Jan 2020

Flash Radiotherapy could Deliver all the Radiation Needed in One Rapid Treatment

Researchers at the University of Pennsylvania have demonstrated that a new approach to delivering radiation could one day mean that cancer patients will be able to receive their entire course of radiotherapy within less than a second as opposed to several weeks.

10 Jan 2020

Fibrosis News and Research

Further Reading

Gene-editing taken to advanced levels in human stem cells

Researchers discover new target for repairing heart after heart attack

Pre-existing anticancer drug could help treat common form of heart failure

60+ organizations to speak as the NASH Summit Boston returns

Deadly infection in cystic fibrosis could be curbed with combination medication

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

Researchers identify liver fibrosis ‘off switch’ in mice

Lung microbes could help predict outcomes in the seriously ill

Lung microbiome of critically ill patients is predictive of clinical outcomes

Cardiac and visual degeneration compensated by taurine supplement

Magnetic nanomaterials may become the basis for new approach to treating liver fibrosis

Study finds new strategies for developing cancer drug

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

Study determines prevalence of fatty liver disease and fibrosis among young adults in the UK

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

Orthopaedic Research UK announces £140,000 investment in biotech startup

Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

Boston researchers develop novel approach to generate intestinal organoids in vitro

Flash Radiotherapy could Deliver all the Radiation Needed in One Rapid Treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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