Malignant News and Research

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Drug combination targets pre-leukemia stem cells

Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells.

12 Sep 2018

New study links stress with biological disease markers in leukemia patients

Patients with chronic lymphocytic leukemia who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease.

12 Sep 2018

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

Barrow Neurological Institute has initiated a $50 million effort, supported by the single largest research grant in the history of brain tumor research, to seek a cure for the deadliest form of brain cancer.

11 Sep 2018

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of immunotherapies for all forms of cancer, will bestow its highest honors on three scientists who have made fundamental contributions to the fields of immunology and cancer immunotherapy.

11 Sep 2018

Innovative robotic system helps in removing large colorectal lesions without surgery

Each year, an estimated 140,000 individuals in the U.S. are diagnosed with colorectal cancer, a malignancy that often develops from a benign polyp into cancer over time.

7 Sep 2018

Enhanced ultrasound can eliminate need for unnecessary biopsies and surgeries, shows study

A simple enhanced ultrasound scan of the kidney is more accurate than computed tomography and magnetic resonance imaging in predicting whether suspicious masses are cancerous -- and can eliminate the need for unnecessary biopsies and surgeries, according to a 10-year study presented today at an international medical conference in Chicago.

7 Sep 2018

New diagnostic tool for difficult-to-detect cancers

A new diagnostic tool is expected to result in better treatment of cancer that is difficult to diagnose. The tool was developed by cancer researchers at Sahlgrenska Academy and doctors at the Sahlgrenska University Hospital, Sweden. Their study, which has been published in JCO Precision Oncology, started with a single cancer patient.

6 Sep 2018

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

New nuclear medicine imaging method could help diagnose widespread tumors

A new nuclear medicine imaging method could help diagnose widespread tumors, such as breast, colon, pancreas, lung and head and neck cancer better than current methods, with less inconvenience to patients and with equal or improved accuracy.

6 Sep 2018

GW researcher receives grant to examine link between liver fluke infection and bile duct cancer

Liver fluke infection is a major public health problem affecting more than 10 million people in Southeast Asia, particularly in Thailand and Laos. Infection has been strongly linked to cholangiocarcinoma, or bile duct cancer, an uncommon but aggressive form of cancer.

5 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Link discovered between tumor genome changes and mortality risk across cancer types

Researchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer.

5 Sep 2018

Improving neurosurgery for malignant brain tumors

Important research by Barrow Neurological Institute neurosurgeons and University of Washington (UW) scientists on novel imaging technology for malignant brain tumors was published in the August issue of the Nature journal, Scientific Reports.

4 Sep 2018

Breakthrough study sheds light on mechanism underlying Warsaw Breakage Syndrome

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme.

3 Sep 2018

Eagle Pharmaceuticals completes enrollment of second clinical study to evaluate safety, efficacy of RYANODEX

Eagle Pharmaceuticals, Inc. today announced completion of enrollment of the Company's second clinical study to further evaluate the safety and efficacy of RYANODEX® (dantrolene sodium for injectable suspension) for the treatment of exertional heat stroke, an investigational new indication for the product.

30 Aug 2018

Cancer-hunting stem cells may be potential drug delivery tool for medulloblastoma

The latest in a series of laboratory breakthroughs could lead to a more effective way to treat the most common brain cancer in children.

30 Aug 2018

WVU dermatologist develops smartphone app to help medical students diagnose melanomas

A dermatologist may distinguish a mole from a tumor based on a glance, the way a cook can tell parsley from cilantro by sniffing it. But medical students don't have enough experience to make such intuitive diagnoses.

29 Aug 2018

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Melanoma and liver cancer are becoming more widespread in Europe and the US. Whilst both diseases progress very differently, they are among the types of cancer which are most likely to be fatal in the Western world.

29 Aug 2018

New approach to assess kidney tumors could prevent patients from undergoing unnecessary surgery

A research team from Roswell Park Comprehensive Cancer Center has discovered a way to use computed tomography imaging to assess kidney tumors that test positive for the biomarker CD117 and accurately determine before surgery, whether the tumor is benign or malignant.

29 Aug 2018

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

Malignant News and Research

Drug combination targets pre-leukemia stem cells

New study links stress with biological disease markers in leukemia patients

Barrow Institute initiates $50 million effort to seek cure for glioblastoma

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

Innovative robotic system helps in removing large colorectal lesions without surgery

Enhanced ultrasound can eliminate need for unnecessary biopsies and surgeries, shows study

New diagnostic tool for difficult-to-detect cancers

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

New nuclear medicine imaging method could help diagnose widespread tumors

GW researcher receives grant to examine link between liver fluke infection and bile duct cancer

Tipping the scales to initiate tumorigenesis in the colon

Link discovered between tumor genome changes and mortality risk across cancer types

Improving neurosurgery for malignant brain tumors

Breakthrough study sheds light on mechanism underlying Warsaw Breakage Syndrome

Eagle Pharmaceuticals completes enrollment of second clinical study to evaluate safety, efficacy of RYANODEX

Cancer-hunting stem cells may be potential drug delivery tool for medulloblastoma

WVU dermatologist develops smartphone app to help medical students diagnose melanomas

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

New approach to assess kidney tumors could prevent patients from undergoing unnecessary surgery

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

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