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Using a simple model to study how serotonin modulates behavior

In popular experience the story of how serotonin modulates the brain might seem simple: pop an antidepressant, serotonin levels go up, mood improves. But neuroscientists acknowledge how little they know about how the neurotransmitter affects circuits and behavior in the incredibly complex human brain.

20 Feb 2020

Dampening effects of overactive immune cells may serve as new treatment for TBI

Targeting overactive immune cells and dampening their effects may serve as a new treatment for treating a traumatic brain injury, according to new research in mice published in JNeurosci.

From Society for Neuroscience 19 Feb 2020

Study uses machine learning to identify personalized brain networks in kids

Machine learning is helping Penn Medicine researchers identify the size and shape of brain networks in individual children, which may be useful for understanding psychiatric disorders.

19 Feb 2020

Altered potassium levels in neurons linked to mood swings in bipolar patients

People with bipolar disorder experience dramatic shifts in mood, oscillating between often debilitating periods of mania and depression.

19 Feb 2020

Research suggests new approach to block tau pathology in FTLD, Alzheimer's

The protein β-arrestin-2 increases the accumulation of neurotoxic tau tangles, a cause several forms of dementia, by interfering with removal of excess tau from the brain, a new study by the University of South Florida Health Morsani College of Medicine found.

17 Feb 2020

Study suggests potential treatment to alleviate disorders of consciousness

A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.

16 Feb 2020

Neuronal necrosis occurs much earlier in Alzheimer’s disease progression than previously thought

Alzheimer's remains the leading cause of dementia in Western societies, with some estimates suggesting that as many as 24 million people worldwide are living with the disease.

13 Feb 2020

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

A light-sensitive protein can restore mitochondria function in fruit flies bearing a gene mutation associated with Parkinson’s disease and relieve its symptoms, report researchers at Juntendo University in the journal Communications Biology.

13 Feb 2020

Accumulated brain protein affects genes in Alzheimer's disease

A new study published in February 2020 in the journal Cell Reports shows how the build-up of specific brain cell proteins are linked to altered gene expression that causes the symptoms of Alzheimer's disease (AD).

11 Feb 2020

Nerve insulation renewed to create long-term learning

A new study published in February 2020, in the journal Nature Neuroscience, shows that short-term learning occurs rapidly, but for it to become a long-term memory, brain cells must form more myelin, an insulating fatty material.

10 Feb 2020

Researchers culture human blood-brain barrier on a chip

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's or cancer from getting into the brain.

10 Feb 2020

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL.

10 Feb 2020

Scientists measure how sensory stimuli are processed in the brain

If we cross a road with our smartphone in view, a car horn or engine noise will startle us. In everyday life we can easily combine information from different senses and shift our attention from one sensory input to another - for example, from seeing to hearing.

10 Feb 2020

Defining neurogenic niche proteome helps identify key regulators of neurogenesis

In mammalian adult brains, neural stem cells are only present in few specific parts, so called niches. Only these niches are capable of generating new neurons.

7 Feb 2020

Breathing pattern may help predict 'when' people begin voluntary action

Have you ever gone ahead and eaten that piece of chocolate, despite yourself?

6 Feb 2020

Unique neuron that computes like a compass identified

It's 5 p.m. as you leave the parking garage at work, but you realize you have no idea which way to turn to travel home. You know where you are and what street your house is on--it's just that you can't remember how to get there.

5 Feb 2020

Flickering light triggers the brain to release signaling chemicals that may help fight Alzheimer's

For over a century, Alzheimer's disease has confounded all attempts to treat it. But in recent years, perplexing experiments using flickering light have shown promise.

4 Feb 2020

Scientists shed new light on neuronal circuits that acquire and update voluntary actions

Two types of neuronal circuit in the brain that acquire and update voluntary actions are much more intertwined than previously thought.

3 Feb 2020

New genetic screen for Huntington’s disease

Huntington’s disease is a genetic disease that is debilitating and progressive leading to severe brain damage and eventual death. In patients with this autosomal dominant disease, there is presence of a protein called the Huntingtin protein that forms clumps within the brain leading to the symptoms of the disease.

30 Jan 2020

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

Typical examples include paralysis due to a spinal cord injury and visual field atrophy or even complete blindness due to optic nerve atrophy in glaucoma patients.

30 Jan 2020

Neuron News and Research

Using a simple model to study how serotonin modulates behavior

Dampening effects of overactive immune cells may serve as new treatment for TBI

Study uses machine learning to identify personalized brain networks in kids

Altered potassium levels in neurons linked to mood swings in bipolar patients

Research suggests new approach to block tau pathology in FTLD, Alzheimer's

Study suggests potential treatment to alleviate disorders of consciousness

Neuronal necrosis occurs much earlier in Alzheimer’s disease progression than previously thought

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

Accumulated brain protein affects genes in Alzheimer's disease

Nerve insulation renewed to create long-term learning

Researchers culture human blood-brain barrier on a chip

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Scientists measure how sensory stimuli are processed in the brain

Defining neurogenic niche proteome helps identify key regulators of neurogenesis

Breathing pattern may help predict 'when' people begin voluntary action

Unique neuron that computes like a compass identified

Flickering light triggers the brain to release signaling chemicals that may help fight Alzheimer's

Scientists shed new light on neuronal circuits that acquire and update voluntary actions

New genetic screen for Huntington’s disease

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

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